Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - contact me Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca on Twitter Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Lumondo Photography Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Pi Art Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Hilbertonians - Creatures on the Hilbert Curve
And she looks like the moon. So close and yet, so far.Future Islandsaim highmore quotes

sky: exciting


DNA on 10th — street art, wayfinding and font


visualization + design

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
The 2019 Pi Day art celebrates digits of `\pi` with hundreds of languages and alphabets. If you're a kid at heart—rejoice—there's a special edition for you!

`\pi` Day 2017 Art Posters - Star charts and extinct animals and plants


Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2019 `\pi` has hundreds of digits, hundreds of languages and a special kids' edition.

Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2018 `\pi` day

Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2017 `\pi` day

Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2016 `\pi` approximation day

Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2016 `\pi` day

Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2015 `\pi` day

Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2014 `\pi` approx day

Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2014 `\pi` day

Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2013 `\pi` day

Pi Day 2017 Art Posters - Star charts and extinct animals and plants
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Circular `\pi` art

On March 14th celebrate `\pi` Day. Hug `\pi`—find a way to do it.

For those who favour `\tau=2\pi` will have to postpone celebrations until July 26th. That's what you get for thinking that `\pi` is wrong. I sympathize with this position and have `\tau` day art too!

If you're not into details, you may opt to party on July 22nd, which is `\pi` approximation day (`\pi` ≈ 22/7). It's 20% more accurate that the official `\pi` day!

Finally, if you believe that `\pi = 3`, you should read why `\pi` is not equal to 3.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
All art posters are available for purchase.
I take custom requests.

Caelum non animum mutant qui trans mare currunt.
—Horace

This year: creatures that don't exist, but once did, in the skies.

This year's `\pi` day song is Exploration by Karminsky Experience Inc. Why? Because "you never know what you'll find on an exploration".

If you like space, you'll love my the 12,000 billion light-year map of clusters, superclusters and voids. Find the biggest nothings in Boötes and Eridanus.

create myths and contribute!

Want to contribute to the mythology behind the constellations in the `\pi` in the sky? Many already have a story, but others still need one. Please submit your stories!

This year I wanted to something more than visuals. Space is vast, so let's fill it with words.

I asked my good friend and poet, Paolo Marcazzan, to collaborate. I described the idea for the art—a universe of stars based on `\pi` and the extinct creatures that live within it—and asked him to find the matching words.

And they could not have been more perfect.




harken to my anger, mother Nyx, for the deceptions of the gods —Aeschylus, Eumenides It’s not so much stifled intent but tussle and fracas in the backstage of the heart spoken in privatives and the high tone of failed mending. Says there is nothing to see and you are seeing it. A truth that likes it here in the caul of light swallowed and us locked in probability or antecedent. Where this run to untold receding and dispersed signature ends in parallels denied l’amor che move il sole e l’altre stelle or silenced music that is number on a brim of echo, capsized chamber drawn into our constellation, and cooling.

—Paolo Marcazzan




author's note

The poem situates the dark as a place for contention and ongoing confrontation. Whether in the recesses of space or heart, the poem probes the territory of distance, absence, uncertainty and muteness. It considers the relational as default positioning of existence (earthly, universal), and that which remains unmet within that context.

Life in its dimension of cross-grained, often broken linearity is juxtaposed with a quote form Dante that references instead his vision of sidereal circularity as the benign force that moves all things in the universe. For the earthbound, the questions and concerns remain those of identity, passage, escape from transiency, and slow tempering of hope.

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news + thoughts

Genome Sciences Center 20th Anniversary Clothing, Music, Drinks and Art

Wed 22-01-2020

Science. Timeliness. Respect.

Read about the design of the clothing, music, drinks and art for the Genome Sciences Center 20th Anniversary Celebration, held on 15 November 2019.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Luke and Mayia wearing limited edition volunteer t-shirts. The pattern reproduces the human genome with chromosomes as spirals. (zoom)

As part of the celebration and with the help of our engineering team, we framed 48 flow cells from the lab.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Precisely engineered frame mounts of flow cells used to sequence genomes in our laboratory. (zoom)

Each flow cell was accompanied by an interpretive plaque explaining the technology behind the flow cell and the sample information and sequence content.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
The plaque at the back of one of the framed Illumina flow cell. This one has sequence from a patient's lymph node diagnosed with Burkitt's lymphoma. (zoom)

Scientific data visualization: Aesthetic for diagrammatic clarity

Mon 13-01-2020

The scientific process works because all its output is empirically constrained.

My chapter from The Aesthetics of Scientific Data Representation, More than Pretty Pictures, in which I discuss the principles of data visualization and connect them to the concept of "quality" introduced by Robert Pirsig in Zen and the Art of Motorcycle Maintenance.

Yearning for the Infinite — Aleph 2

Mon 18-11-2019

Discover Cantor's transfinite numbers through my music video for the Aleph 2 track of Max Cooper's Yearning for the Infinite (album page, event page).

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Yearning for the Infinite, Max Cooper at the Barbican Hall, London. Track Aleph 2. Video by Martin Krzywinski. Photo by Michal Augustini. (more)

I discuss the math behind the video and the system I built to create the video.

Hidden Markov Models

Mon 18-11-2019

Everything we see hides another thing, we always want to see what is hidden by what we see.
—Rene Magritte

A Hidden Markov Model extends a Markov chain to have hidden states. Hidden states are used to model aspects of the system that cannot be directly observed and themselves form a Markov chain and each state may emit one or more observed values.

Hidden states in HMMs do not have to have meaning—they can be used to account for measurement errors, compress multi-modal observational data, or to detect unobservable events.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Hidden Markov Models. (read)

In this column, we extend the cell growth model from our Markov Chain column to include two hidden states: normal and sedentary.

We show how to calculate forward probabilities that can predict the most likely path through the HMM given an observed sequence.

Grewal, J., Krzywinski, M. & Altman, N. (2019) Points of significance: Hidden Markov Models. Nature Methods 16:795–796.

Background reading

Altman, N. & Krzywinski, M. (2019) Points of significance: Markov Chains. Nature Methods 16:663–664.

Hola Mundo Cover

Sat 21-09-2019

My cover design for Hola Mundo by Hannah Fry. Published by Blackie Books.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Hola Mundo by Hannah Fry. Cover design is based on my 2013 `\pi` day art. (read)

Curious how the design was created? Read the full details.

Markov Chains

Tue 30-07-2019

You can look back there to explain things,
but the explanation disappears.
You'll never find it there.
Things are not explained by the past.
They're explained by what happens now.
—Alan Watts

A Markov chain is a probabilistic model that is used to model how a system changes over time as a series of transitions between states. Each transition is assigned a probability that defines the chance of the system changing from one state to another.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Markov Chains. (read)

Together with the states, these transitions probabilities define a stochastic model with the Markov property: transition probabilities only depend on the current state—the future is independent of the past if the present is known.

Once the transition probabilities are defined in matrix form, it is easy to predict the distribution of future states of the system. We cover concepts of aperiodicity, irreducibility, limiting and stationary distributions and absorption.

This column is the first part of a series and pairs particularly well with Alan Watts and Blond:ish.

Grewal, J., Krzywinski, M. & Altman, N. (2019) Points of significance: Markov Chains. Nature Methods 16:663–664.