Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - contact me Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca on Twitter Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Lumondo Photography Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Pi Art Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Hilbertonians - Creatures on the Hilbert Curve
Trance opera—Spente le Stellebe dramaticmore quotes

3.14: fun


In Silico Flurries: Computing a world of snow. Scientific American. 23 December 2017


visualization + design

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
The 2018 Pi Day art celebrates the 30th anniversary of `\pi` day and connects friends stitching road maps from around the world. Pack a sandwich and let's go!

`\pi` Day 2018 Art Posters - Stitched city road maps from around the world


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2018 `\pi` day shrinks the world and celebrates road trips by stitching streets from around the world together. In this version, we look at the boonies, burbs and boutique of `\pi` by drawing progressively denser patches of streets. Let's go places.

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2017 `\pi` day

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2016 `\pi` approximation day

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2016 `\pi` day

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2015 `\pi` day

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2014 `\pi` approx day

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2014 `\pi` day

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2013 `\pi` day

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Circular `\pi` art

On March 14th celebrate `\pi` Day. Hug `\pi`—find a way to do it.

For those who favour `\tau=2\pi` will have to postpone celebrations until July 26th. That's what you get for thinking that `\pi` is wrong.

If you're not into details, you may opt to party on July 22nd, which is `\pi` approximation day (`\pi` ≈ 22/7). It's 20% more accurate that the official `\pi` day!

Finally, if you believe that `\pi = 3`, you should read why `\pi` is not equal to 3.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
All art posters are available for purchase.
I take custom requests.

And if you've got to sleep a moment on the road
I will steer for you
And if you want to work the street alone
I'll disappear for you
—Leonard Cohen (I'm Your Man)

This year's is the 30th anniversary of `\pi` day. The theme of the art is bridging the world and making friends. So myself I again team up with my long-time friend and collaborator Jake Lever. I worled with Jake on the snowflake catalogue, where we build a world of flakes.

And so, this year we also build a world. We start with all the roads in the world and stitch them together in brand new ways. And if you walk more than 1 km in this world, you'll likely to be transported somewhere completely different.

This year's `\pi` day song is Trance Groove: Paris. Why? Because it's worth to go to new places—real or imagined.

city strips

Amsterdam,Bangkok,Beijing,Berlin,Copenhagen,Edinburgh,Hong Kong,Johannesburg,Marrakesh and Melbourne


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 10 digits of `\pi`. City strips for Amsterdam, Bangkok, Beijing, Berlin, Copenhagen, Edinburgh, Hong Kong, Johannesburg, Marrakesh and Melbourne. (BUY ARTWORK)

Moscow,Mumbai,Nairobi,New Delhi,Nice,Prague,Rome,Stockholm,Vancouver and Warsaw


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 10 digits of `\pi`. City strips for Moscow, Mumbai, Nairobi, New Delhi, Nice, Prague, Rome, Stockholm, Vancouver and Warsaw. (BUY ARTWORK)

Barcelona,Cairo,Dublin,Lisbon,Los Angeles,New York,Paris,San Francisco,Saint Petersburg and Vienna


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 10 digits of `\pi`. City strips for Barcelona, Cairo, Dublin, Lisbon, Los Angeles, New York, Paris, San Francisco, Saint Petersburg and Vienna. (BUY ARTWORK)

Buenos Aires,Doha,Jakarta,Madrid,Mexico City,Osaka,Sao Paolo,Shanghai,Sydney and Toronto


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 10 digits of `\pi`. City strips for Buenos Aires, Doha, Jakarta, Madrid, Mexico City, Osaka, Sao Paolo, Shanghai, Sydney and Toronto. (BUY ARTWORK)

boonies, burbs and boutiques


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
The boonies, burbs and boutiques of `\pi`. Progressively denser patches of streets from various cities smoothly progress from nowhere to somewhere. (BUY ARTWORK)

world patches

10 cities

Berlin,Cairo,Hong Kong,London,Moscow,New York,Paris,Rome,Sydney and Tokyo


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 36 digits of `\pi`. A world patch using Berlin, Cairo, Hong Kong, London, Moscow, New York, Paris, Rome, Sydney and Tokyo. (BUY ARTWORK)

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 36 digits of `\pi`. A world patch using Berlin, Cairo, Hong Kong, London, Moscow, New York, Paris, Rome, Sydney and Tokyo. (BUY ARTWORK)

Amsterdam,Copenhagen,Dublin,Istanbul,Lisbon,Madrid,Melbourne,Nice,Prague and San Francisco.


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 36 digits of `\pi`. A world patch using Amsterdam, Copenhagen, Dublin, Istanbul, Lisbon, Madrid, Melbourne, Nice, Prague and San Francisco. (BUY ARTWORK)

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 36 digits of `\pi`. A world patch using Amsterdam, Copenhagen, Dublin, Istanbul, Lisbon, Madrid, Melbourne, Nice, Prague and San Francisco. (BUY ARTWORK)

Amsterdam,Doha,Marrakesh,Mumbai,Nairobi,Rome,San Francisco,Seoul,Shanghai and Vancouver


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 36 digits of `\pi`. A world patch using Amsterdam, Doha, Marrakesh, Mumbai, Nairobi, Rome, San Francisco, Seoul, Shanghai and Vancouver (BUY ARTWORK)

Dublin,Istanbul,Lisbon,Marrakesh,Osaka,Paris,Prague,Sydney,Vancouver and Vienna


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 36 digits of `\pi`. A world patch using Dublin, Istanbul, Lisbon, Marrakesh, Osaka, Paris, Prague, Sydney, Vancouver and Vienna (BUY ARTWORK)

2 cities

Melbourne and Nice


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 36 digits of `\pi`. A world patch using Melbourne and Nice. (BUY ARTWORK)

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 36 digits of `\pi`. A world patch using Melbourne and Nice. (BUY ARTWORK)

Paris and Prague


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 36 digits of `\pi`. A world patch using Paris and Prague. (BUY ARTWORK)

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 36 digits of `\pi`. A world patch using Paris and Prague. (BUY ARTWORK)

Bangkok and Sao Paolo


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Bangkok and Sao Paolo. (zoom)

Berlin and Jakarta


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Berlin and Jakarta. (zoom)

Berlin and Mumbai


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Berlin and Mumbai. (zoom)

Cairo and Istanbul


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Cairo and Istanbul. (zoom)

Cairo and Jakarta


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Cairo and Jakarta. (zoom)

Doha and Lisbon


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Doha and Lisbon. (zoom)

Dublin and Istanbul


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Dublin and Istanbul. (zoom)

Dublin and Mumbai


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Dublin and Mumbai. (zoom)

Hong Kong and Jakarta


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Hong Kong and Jakarta. (zoom)

Istanbul and Paris


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Istanbul and Paris. (zoom)

Jakarta and San Francisco


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Jakarta and San Francisco. (zoom)

Johannesburg and Marrakesh


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Johannesburg and Marrakesh. (zoom)

Johannesburg and Nice


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Johannesburg and Nice. (zoom)

Lisbon and Seoul


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Lisbon and Seoul. (zoom)

Marrakesh and New Delhi


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Marrakesh and New Delhi. (zoom)

Marrakesh and Tokyo


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Marrakesh and Tokyo. (zoom)

Mumbai and Nairobi


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Mumbai and Nairobi. (zoom)

Mumbai and Vancouver


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Mumbai and Vancouver. (zoom)

Toronto and Vienna


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Toronto and Vienna. (zoom)
VIEW ALL

news + thoughts

Optimal experimental design

Tue 31-07-2018
Customize the experiment for the setting instead of adjusting the setting to fit a classical design.

The presence of constraints in experiments, such as sample size restrictions, awkward blocking or disallowed treatment combinations may make using classical designs very difficult or impossible.

Optimal design is a powerful, general purpose alternative for high quality, statistically grounded designs under nonstandard conditions.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Optimal experimental design. (read)

We discuss two types of optimal designs (D-optimal and I-optimal) and show how it can be applied to a scenario with sample size and blocking constraints.

Smucker, B., Krzywinski, M. & Altman, N. (2018) Points of significance: Optimal experimental design Nature Methods 15:599–600.

Background reading

Krzywinski, M., Altman, N. (2014) Points of significance: Two factor designs. Nature Methods 11:1187–1188.

Krzywinski, M. & Altman, N. (2014) Points of significance: Analysis of variance (ANOVA) and blocking. Nature Methods 11:699–700.

Krzywinski, M. & Altman, N. (2014) Points of significance: Designing comparative experiments. Nature Methods 11:597–598.

The Whole Earth Cataloguer

Mon 30-07-2018
All the living things.

An illustration of the Tree of Life, showing some of the key branches.

The tree is drawn as a DNA double helix, with bases colored to encode ribosomal RNA genes from various organisms on the tree.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
The circle of life. (read, zoom)

All living things on earth descended from a single organism called LUCA (last universal common ancestor) and inherited LUCA’s genetic code for basic biological functions, such as translating DNA and creating proteins. Constant genetic mutations shuffled and altered this inheritance and added new genetic material—a process that created the diversity of life we see today. The “tree of life” organizes all organisms based on the extent of shuffling and alteration between them. The full tree has millions of branches and every living organism has its own place at one of the leaves in the tree. The simplified tree shown here depicts all three kingdoms of life: bacteria, archaebacteria and eukaryota. For some organisms a grey bar shows when they first appeared in the tree in millions of years (Ma). The double helix winding around the tree encodes highly conserved ribosomal RNA genes from various organisms.

Johnson, H.L. (2018) The Whole Earth Cataloguer, Sactown, Jun/Jul, p. 89

Why we can't give up this odd way of typing

Mon 30-07-2018
All fingers report to home row.

An article about keyboard layouts and the history and persistence of QWERTY.

My Carpalx keyboard optimization software is mentioned along with my World's Most Difficult Layout: TNWMLC. True typing hell.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
TNWMLC requires seriously flexible digits. It’s 87% more difficult than using a standard Qwerty keyboard, according to Martin Krzywinski, who created it (Credit: Ben Nelms). (read)

McDonald, T. (2018) Why we can't give up this odd way of typing, BBC, 25 May 2018.

Molecular Case Studies Cover

Fri 06-07-2018

The theme of the April issue of Molecular Case Studies is precision oncogenomics. We have three papers in the issue based on work done in our Personalized Oncogenomics Program (POG).

The covers of Molecular Case Studies typically show microscopy images, with some shown in a more abstract fashion. There's also the occasional Circos plot.

I've previously taken a more fine-art approach to cover design, such for those of Nature, Genome Research and Trends in Genetics. I've used microscopy images to create a cover for PNAS—the one that made biology look like astrophysics—and thought that this is kind of material I'd start with for the MCS cover.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Cover design for Apr 2018 issue of Molecular Case Studies. (details)

Happy 2018 `\tau` Day—Art for everyone

Wed 27-06-2018
Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
You know what day it is. (details)

Universe Superclusters and Voids

Mon 25-06-2018

A map of the nearby superclusters and voids in the Unvierse.

By "nearby" I mean within 6,000 million light-years.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
The Universe — Superclustesr and Voids. The two supergalactic hemispheres showing Abell clusters, superclusters and voids within a distance of 6,000 million light-years from the Milky Way. (details)