Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - contact me Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca on Twitter Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Lumondo Photography Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Pi Art Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Hilbertonians - Creatures on the Hilbert Curve
Thoughts rearrange, familiar now strange.Holly Golightly & The Greenhornes break flowersmore quotes

stars: exciting


In Silico Flurries: Computing a world of snow. Scientific American. 23 December 2017


visualization + design

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
The 2018 Pi Day art celebrates the 30th anniversary of `\pi` day and connects friends stitching road maps from around the world. Pack a sandwich and let's go!

`\pi` Day 2018 Art Posters - Stitched city road maps from around the world


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2018 `\pi` day shrinks the world and celebrates road trips by stitching streets from around the world together. In this version, we look at the boonies, burbs and boutique of `\pi` by drawing progressively denser patches of streets. Let's go places.

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2017 `\pi` day

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2016 `\pi` approximation day

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2016 `\pi` day

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2015 `\pi` day

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2014 `\pi` approx day

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2014 `\pi` day

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2013 `\pi` day

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Circular `\pi` art

On March 14th celebrate `\pi` Day. Hug `\pi`—find a way to do it.

For those who favour `\tau=2\pi` will have to postpone celebrations until July 26th. That's what you get for thinking that `\pi` is wrong.

If you're not into details, you may opt to party on July 22nd, which is `\pi` approximation day (`\pi` ≈ 22/7). It's 20% more accurate that the official `\pi` day!

Finally, if you believe that `\pi = 3`, you should read why `\pi` is not equal to 3.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
All art posters are available for purchase.
I take custom requests.

And if you've got to sleep a moment on the road
I will steer for you
And if you want to work the street alone
I'll disappear for you
—Leonard Cohen (I'm Your Man)

This year's is the 30th anniversary of `\pi` day. The theme of the art is bridging the world and making friends. So myself I again team up with my long-time friend and collaborator Jake Lever. I worled with Jake on the snowflake catalogue, where we build a world of flakes.

And so, this year we also build a world. We start with all the roads in the world and stitch them together in brand new ways. And if you walk more than 1 km in this world, you'll likely to be transported somewhere completely different.

This year's `\pi` day song is Trance Groove: Paris. Why? Because it's worth to go to new places—real or imagined.

city strips

Amsterdam,Bangkok,Beijing,Berlin,Copenhagen,Edinburgh,Hong Kong,Johannesburg,Marrakesh and Melbourne


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 10 digits of `\pi`. City strips for Amsterdam, Bangkok, Beijing, Berlin, Copenhagen, Edinburgh, Hong Kong, Johannesburg, Marrakesh and Melbourne. (BUY ARTWORK)

Moscow,Mumbai,Nairobi,New Delhi,Nice,Prague,Rome,Stockholm,Vancouver and Warsaw


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 10 digits of `\pi`. City strips for Moscow, Mumbai, Nairobi, New Delhi, Nice, Prague, Rome, Stockholm, Vancouver and Warsaw. (BUY ARTWORK)

Barcelona,Cairo,Dublin,Lisbon,Los Angeles,New York,Paris,San Francisco,Saint Petersburg and Vienna


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 10 digits of `\pi`. City strips for Barcelona, Cairo, Dublin, Lisbon, Los Angeles, New York, Paris, San Francisco, Saint Petersburg and Vienna. (BUY ARTWORK)

Buenos Aires,Doha,Jakarta,Madrid,Mexico City,Osaka,Sao Paolo,Shanghai,Sydney and Toronto


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 10 digits of `\pi`. City strips for Buenos Aires, Doha, Jakarta, Madrid, Mexico City, Osaka, Sao Paolo, Shanghai, Sydney and Toronto. (BUY ARTWORK)

boonies, burbs and boutiques


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
The boonies, burbs and boutiques of `\pi`. Progressively denser patches of streets from various cities smoothly progress from nowhere to somewhere. (BUY ARTWORK)

world patches

10 cities

Berlin,Cairo,Hong Kong,London,Moscow,New York,Paris,Rome,Sydney and Tokyo


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 36 digits of `\pi`. A world patch using Berlin, Cairo, Hong Kong, London, Moscow, New York, Paris, Rome, Sydney and Tokyo. (BUY ARTWORK)

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 36 digits of `\pi`. A world patch using Berlin, Cairo, Hong Kong, London, Moscow, New York, Paris, Rome, Sydney and Tokyo. (BUY ARTWORK)

Amsterdam,Copenhagen,Dublin,Istanbul,Lisbon,Madrid,Melbourne,Nice,Prague and San Francisco.


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 36 digits of `\pi`. A world patch using Amsterdam, Copenhagen, Dublin, Istanbul, Lisbon, Madrid, Melbourne, Nice, Prague and San Francisco. (BUY ARTWORK)

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 36 digits of `\pi`. A world patch using Amsterdam, Copenhagen, Dublin, Istanbul, Lisbon, Madrid, Melbourne, Nice, Prague and San Francisco. (BUY ARTWORK)

Amsterdam,Doha,Marrakesh,Mumbai,Nairobi,Rome,San Francisco,Seoul,Shanghai and Vancouver


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 36 digits of `\pi`. A world patch using Amsterdam, Doha, Marrakesh, Mumbai, Nairobi, Rome, San Francisco, Seoul, Shanghai and Vancouver (BUY ARTWORK)

Dublin,Istanbul,Lisbon,Marrakesh,Osaka,Paris,Prague,Sydney,Vancouver and Vienna


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 36 digits of `\pi`. A world patch using Dublin, Istanbul, Lisbon, Marrakesh, Osaka, Paris, Prague, Sydney, Vancouver and Vienna (BUY ARTWORK)

2 cities

Melbourne and Nice


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 36 digits of `\pi`. A world patch using Melbourne and Nice. (BUY ARTWORK)

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 36 digits of `\pi`. A world patch using Melbourne and Nice. (BUY ARTWORK)

Paris and Prague


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 36 digits of `\pi`. A world patch using Paris and Prague. (BUY ARTWORK)

Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
On the road with 36 digits of `\pi`. A world patch using Paris and Prague. (BUY ARTWORK)

Bangkok and Sao Paolo


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Bangkok and Sao Paolo. (zoom)

Berlin and Jakarta


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Berlin and Jakarta. (zoom)

Berlin and Mumbai


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Berlin and Mumbai. (zoom)

Cairo and Istanbul


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Cairo and Istanbul. (zoom)

Cairo and Jakarta


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Cairo and Jakarta. (zoom)

Doha and Lisbon


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Doha and Lisbon. (zoom)

Dublin and Istanbul


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Dublin and Istanbul. (zoom)

Dublin and Mumbai


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Dublin and Mumbai. (zoom)

Hong Kong and Jakarta


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Hong Kong and Jakarta. (zoom)

Istanbul and Paris


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Istanbul and Paris. (zoom)

Jakarta and San Francisco


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Jakarta and San Francisco. (zoom)

Johannesburg and Marrakesh


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Johannesburg and Marrakesh. (zoom)

Johannesburg and Nice


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Johannesburg and Nice. (zoom)

Lisbon and Seoul


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Lisbon and Seoul. (zoom)

Marrakesh and New Delhi


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Marrakesh and New Delhi. (zoom)

Marrakesh and Tokyo


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Marrakesh and Tokyo. (zoom)

Mumbai and Nairobi


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Mumbai and Nairobi. (zoom)

Mumbai and Vancouver


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Mumbai and Vancouver. (zoom)

Toronto and Vienna


Pi Day 2018 Art Posters  - Stitched city road maps from around the world
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
On the road with 36 digits of `\pi`. A world patch using Toronto and Vienna. (zoom)
VIEW ALL

news + thoughts

Find and snap to colors in an image

Sat 29-12-2018

One of my color tools, the colorsnap application snaps colors in an image to a set of reference colors and reports their proportion.

Below is Times Square rendered using the colors of the MTA subway lines.


Colors used by the New York MTA subway lines.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Times Square in New York City.
Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Times Square in New York City rendered using colors of the MTA subway lines.
Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Granger rainbow snapped to subway lines colors from four cities. (zoom)

Take your medicine ... now

Wed 19-12-2018

Drugs could be more effective if taken when the genetic proteins they target are most active.

Design tip: rediscover CMYK primaries.

More of my American Scientific Graphic Science designs

Ruben et al. A database of tissue-specific rhythmically expressed human genes has potential applications in circadian medicine Science Translational Medicine 10 Issue 458, eaat8806.

Predicting with confidence and tolerance

Wed 07-11-2018
I abhor averages. I like the individual case. —J.D. Brandeis.

We focus on the important distinction between confidence intervals, typically used to express uncertainty of a sampling statistic such as the mean and, prediction and tolerance intervals, used to make statements about the next value to be drawn from the population.

Confidence intervals provide coverage of a single point—the population mean—with the assurance that the probability of non-coverage is some acceptable value (e.g. 0.05). On the other hand, prediction and tolerance intervals both give information about typical values from the population and the percentage of the population expected to be in the interval. For example, a tolerance interval can be configured to tell us what fraction of sampled values (e.g. 95%) will fall into an interval some fraction of the time (e.g. 95%).

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Predicting with confidence and tolerance. (read)

Altman, N. & Krzywinski, M. (2018) Points of significance: Predicting with confidence and tolerance Nature Methods 15:843–844.

Background reading

Krzywinski, M. & Altman, N. (2013) Points of significance: Importance of being uncertain. Nature Methods 10:809–810.

4-day Circos course

Wed 31-10-2018

A 4-day introductory course on genome data parsing and visualization using Circos. Prepared for the Bioinformatics and Genome Analysis course in Institut Pasteur Tunis, Tunis, Tunisia.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Composite of the kinds of images you will learn to make in this course.

Oryza longistaminata genome cake

Mon 24-09-2018

Data visualization should be informative and, where possible, tasty.

Stefan Reuscher from Bioscience and Biotechnology Center at Nagoya University celebrates a publication with a Circos cake.

The cake shows an overview of a de-novo assembled genome of a wild rice species Oryza longistaminata.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Circos cake celebrating Reuscher et al. 2018 publication of the Oryza longistaminata genome.

Optimal experimental design

Tue 31-07-2018
Customize the experiment for the setting instead of adjusting the setting to fit a classical design.

The presence of constraints in experiments, such as sample size restrictions, awkward blocking or disallowed treatment combinations may make using classical designs very difficult or impossible.

Optimal design is a powerful, general purpose alternative for high quality, statistically grounded designs under nonstandard conditions.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Optimal experimental design. (read)

We discuss two types of optimal designs (D-optimal and I-optimal) and show how it can be applied to a scenario with sample size and blocking constraints.

Smucker, B., Krzywinski, M. & Altman, N. (2018) Points of significance: Optimal experimental design Nature Methods 15:599–600.

Background reading

Krzywinski, M., Altman, N. (2014) Points of significance: Two factor designs. Nature Methods 11:1187–1188.

Krzywinski, M. & Altman, N. (2014) Points of significance: Analysis of variance (ANOVA) and blocking. Nature Methods 11:699–700.

Krzywinski, M. & Altman, N. (2014) Points of significance: Designing comparative experiments. Nature Methods 11:597–598.