Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - contact me Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca on Twitter Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Lumondo Photography Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Pi Art Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Hilbertonians - Creatures on the Hilbert Curve
This love loves love. It's a strange love, strange love.Liz Fraserfind a way to lovemore quotes

4ness: beautiful


EMBO Practical Course: Bioinformatics and Genome Analysis, 5–17 June 2017.


visualization + design

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
The 2017 Pi Day art imagines the digits of Pi as a star catalogue with constellations of extinct animals and plants. The work is featured in the article Pi in the Sky at the Scientific American SA Visual blog.

The art of Pi (`\pi`), Phi (`\phi`) and `e`


Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2017 `\pi` day

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2016 `\pi` approximation day

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2016 `\pi` day

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2015 `\pi` day

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2014 `\pi` approx day

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2014 `\pi` day

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2013 `\pi` day

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Circular `\pi` art

Like music with numbers? Here's a short list of some of my favourite songs that have numbers in their lyrics. Absolutely none of them is about bottles of beer.

music with numbers

1 — Numbers, Smoke City | This song is entirely composed of references to different numbers. The bonus? It's both in English and Portuguese. I love the way it ends—"Isn't it beautiful out here?".

Un
Un
Four
Five

Fifteen
Quinze
Seventeen
Seven

...

Tres
forty nine

Isn't it beautiful out here?
Isn't it beautiful out here?
Isn't it beautiful out here?

2 — 99 luftbaloons, Nena | The numerical classic.

Hast du etwas Zeit für mich
Dann singe ich ein Lied für dich
Von 99 Luftballons

3 — One, Aimee Mann | Beautiful mathematics of relationships using small numbers.

One is the lonliest number that you'll ever do. Two can be as bad as one, it's the lonliest number since the number one.

4 — Angels at My Door, Una | Long sequences of numbers.

58, 56, 54 angels at my door.
63, 62, 61, 60, 59, 58 angels at my gate.

5 — Tricky, Tricky, Royksopp | Number words about the fearful six from Norway.

Six afraid of seven 'cause seven, eight, nine
I'm about to lose it the second time

6 — Pt vs Ys, Yoshinori Sunahara | The first four numbers, in German, are this song's lyrics.

Eins, zwei, drei, vier.

7 — Der Kommissar, Falco | Unlike the previous song, this one starts with a German count (doesn't get to vier, though) and just gets better from there.

Two, three, four
Eins, zwei, drei
Na, es is nix dabei
Na, wenn ich euch erzähl' die G'schicht'

8 — 2wicky, Hooverphonic | The numbers likely reference the Prophet-600 and SH-101 synthesizers.

Prophet 60091.
Before we start you should know that you're not the only one who can hurt me.
SH10151.
This is the serial number of our orbital gun.
SH10151.
You better be sure before you leave me for another one.

9 — Straight to Number One, Touch and Go | Something to listen to after midnight.

Fingers, four, play, three, to number one.

10 — The Beat Experience, Pepe Deluxe | I am reminded of this song at too many academic seminars.

Here we are now, at the middle, of the fourth large part of this talk.
More and more I have the feeling that we are getting nowhere.
Slowly, as the talk goes on, we are getting nowhere.
And that is a pleasure.

It is not irritating where one is.
It is only irritating to think one would like to be somewhere else.
Here we are now, a little bit after the middle, of the fourth large part of this talk.

11 — Thousand Kisses Deep, Leonard Cohen | A list of songs that doesn't include one by Cohen is not worth reading. The sentiment of a thousand kisses is as old as lips existed. Catullus wrote to Lesbia "da mi basia mille, deinde centum, dein mille altera, dein secunda centum, deinde usque altera mille, deinde centum" [Give me a thousand kisses, then a hundred, then another thousand, then a second hundred, then yet another thousand, then a hundred.] Well, you get the idea.

And sometimes when the night is slow,
The wretched and the meek,
We gather up our hearts and go,
A Thousand Kisses Deep.

12 — Six Seven Times, Flunk | Curiously the product here is 42. This song is the answer to life.

You've got it all
Six seven times
You've got it all
Makes me feel so fine
And it's all there is

13 — 7 seconds, Youssou N'Dour | Dreamy references to a short period of time.

7 seconds away. Just as long as I stay. I'll be waiting.

14 — 100 Billion Stars, Lux | Something to relax to while you ponder insignificance.

15 — First Picture, Nikolaj Grandjean | First is the most memorable number.

I remember
The first picture
One million different shadows
Where we've been around the willows

16 — Millions of Millions, Music for a French Elevator | Very desirable. And I can't believe I transcribed the whole thing.

5.50 million dollars, 2.6775 and very desirable 8 million dollars 5.6 million and 2.4 million 3.4 million and 2.9 million 1.2 would've amounted to 4 million 1.2 million 19.4 million 6.6 million 5.275 million 1.2 million 3-and-a-half million dollars 6.453 million 8 million 5.050 million 1.4 million close to a million dollars 933.5 million 3.8 million 5 million dollars 2-and-a-half million 600 million dollars can you shut the door? 3-and-a-half million dollars 2.5 million .050 million 572,750 thousand 5.050 million 3.8 million 3 million 150 thousand 8 million 419.5 million

17 — Love Potion #9, The Searchers | I started kissing everythying in sight.

It smelled like turpentine, it looked like Indian ink
I held my nose, I closed my eyes, I took a drink.

18 — 93 Million Miles, Luan Santana feat. John Kip | A little sticky, a little sweet but it makes up for the fact that much of it is in Portuguese.

But the absence of the light is a necessary part.

VIEW ALL

news + thoughts

Happy 2017 `\pi` Day—Star Charts, Creatures Once Living and a Poem

Tue 14-03-2017


on a brim of echo,

capsized chamber
drawn into our constellation, and cooling.
—Paolo Marcazzan

Celebrate `\pi` Day (March 14th) with star chart of the digits. The charts draw 40,000 stars generated from the first 12 million digits.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
12,000,000 digits of `\pi` interpreted as a star catalogue. (details)

The 80 constellations are extinct animals and plants. Here you'll find old friends and new stories. Read about how Desmodus is always trying to escape or how Megalodon terrorizes the poor Tecopa! Most constellations have a story.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Find friends and stories among the 80 constellations of extinct animals and plants. Oh look, a Dodo guardings his eggs! (details)

This year I collaborate with Paolo Marcazzan, a Canadian poet, who contributes a poem, Of Black Body, about space and things we might find and lose there.

Check out art from previous years: 2013 `\pi` Day and 2014 `\pi` Day, 2015 `\pi` Day and and 2016 `\pi` Day.

Data in New Dimensions: convergence of art, genomics and bioinformatics

Tue 07-03-2017

Art is science in love.
— E.F. Weisslitz

A behind-the-scenes look at the making of our stereoscopic images which were at display at the AGBT 2017 Conference in February. The art is a creative collaboration with Becton Dickinson and The Linus Group.

Its creation began with the concept of differences and my writeup of the creative and design process focuses on storytelling and how concept of differences is incorporated into the art.

Oh, and this might be a good time to pick up some red-blue 3D glasses.

BD Genomics 3D art exhibit - AGBT 2017 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
A stereoscopic image and its interpretive panel of single-cell transcriptomes of blood cells: diseased versus healthy control.

Interpreting P values

Thu 02-03-2017
A P value measures a sample’s compatibility with a hypothesis, not the truth of the hypothesis.

This month we continue our discussion about `P` values and focus on the fact that `P` value is a probability statement about the observed sample in the context of a hypothesis, not about the hypothesis being tested.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Interpreting P values. (read)

Given that we are always interested in making inferences about hypotheses, we discuss how `P` values can be used to do this by way of the Benjamin-Berger bound, `\bar{B}` on the Bayes factor, `B`.

Heuristics such as these are valuable in helping to interpret `P` values, though we stress that `P` values vary from sample to sample and hence many sources of evidence need to be examined before drawing scientific conclusions.

Altman, N. & Krzywinski, M. (2017) Points of Significance: Interpreting P values. Nature Methods 14:213–214.

Background reading

Krzywinski, M. & Altman, N. (2017) Points of significance: P values and the search for significance. Nature Methods 14:3–4.

Krzywinski, M. & Altman, N. (2013) Points of significance: Significance, P values and t–tests. Nature Methods 10:1041–1042.

...more about the Points of Significance column

Snellen Charts—Typography to Really Look at

Sat 18-02-2017

Another collection of typographical posters. These ones really ask you to look.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Snellen charts designed using physical constants, Braille and elemental abundances in the universe and human body.

The charts show a variety of interesting symbols and operators found in science and math. The design is in the style of a Snellen chart and typset with the Rockwell font.

Essentials of Data Visualization—8-part video series

Fri 17-02-2017
Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca

In collaboration with the Phil Poronnik and Kim Bell-Anderson at the University of Sydney, I'm delighted to share with you our 8-part video series project about thinking about drawing data and communicating science.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Essentials of Data Visualization: Thinking about drawing data and communicating science.

We've created 8 videos, each focusing on a different essential idea in data visualization: encoding, shapes, color, uncertainty, design, drawing missing or unobserved data, labels and process.

The videos were designed as teaching materials. Each video comes with a slide deck and exercises.

P values and the search for significance

Mon 16-01-2017
Little P value
What are you trying to say
Of significance?
—Steve Ziliak

We've written about P values before and warned readers about common misconceptions about them, which are so rife that the American Statistical Association itself has a long statement about them.

This month is our first of a two-part article about P values. Here we look at 'P value hacking' and 'data dredging', which are questionable practices that invalidate the correct interpretation of P values.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: P values and the search for significance. (read)

We also illustrate how P values can lead us astray by asking "What is the smallest P value we can expect if the null hypothesis is true but we have done many tests, either explicitly or implicitly?"

Incidentally, this is our first column in which the standfirst is a haiku.

Altman, N. & Krzywinski, M. (2017) Points of Significance: P values and the search for significance. Nature Methods 14:3–4.

Background reading

Krzywinski, M. & Altman, N. (2013) Points of significance: Significance, P values and t–tests. Nature Methods 10:1041–1042.

...more about the Points of Significance column