Lips that taste of tears, they say, are the best for kissing.get crankymore quotes

stars: fun

In Silico Flurries: Computing a world of snow. Scientific American. 23 December 2017

visualization + design

The 2018 Pi Day art celebrates the 30th anniversary of $\pi$ day and connects friends stitching road maps from around the world. Pack a sandwich and let's go!

$\pi$ Day 2017 Art Posters - Star charts and extinct animals and plants

2018 $\pi$ day shrinks the world and celebrates road trips by stitching streets from around the world together. In this version, we look at the boonies, burbs and boutique of $\pi$ by drawing progressively denser patches of streets. Let's go places.
2017 $\pi$ day
2016 $\pi$ approximation day
2016 $\pi$ day
2015 $\pi$ day
2014 $\pi$ approx day
2014 $\pi$ day
2013 $\pi$ day
Circular $\pi$ art

On March 14th celebrate $\pi$ Day. Hug $\pi$—find a way to do it.

For those who favour $\tau=2\pi$ will have to postpone celebrations until July 26th. That's what you get for thinking that $\pi$ is wrong.

If you're not into details, you may opt to party on July 22nd, which is $\pi$ approximation day ($\pi$ ≈ 22/7). It's 20% more accurate that the official $\pi$ day!

Finally, if you believe that $\pi = 3$, you should read why $\pi$ is not equal to 3.

All art posters are available for purchase.
I take custom requests.

Caelum non animum mutant qui trans mare currunt.
—Horace

This year: creatures that don't exist, but once did, in the skies.

And a poem Of Black Body.

This year's $\pi$ day song is Exploration by Karminsky Experience Inc. Why? Because "you never know what you'll find on an exploration".

If you like space, you'll love my the 12,000 billion light-year map of clusters, superclusters and voids. Find the biggest nothings in Boötes and Eridanus.

create myths and contribute!

Want to contribute to the mythology behind the constellations in the $\pi$ in the sky? Many already have a story, but others still need one. Please submit your stories!

For each chart projection (plane carrée, azimuthal equidistant and Hammer/Aitoff) there are three color versions available: space dark blue, space black and sepia.

color

Star chart of the first 12,000,000 digits of $\pi$. The 80 constellations honor extinct animals and plants. Plate carrée projection. (BUY ARTWORK)
Star chart of the first 12,000,000 digits of $\pi$. The 80 constellations honor extinct animals and plants. Azimuthal equidistant projection. (BUY ARTWORK)
Star chart of the first 12,000,000 digits of $\pi$. The 80 constellations honor extinct animals and plants. Hammer/Aitoff elliptical projection. (BUY ARTWORK)

black & white

Star chart of the first 12,000,000 digits of $\pi$. The 80 constellations honor extinct animals and plants. Plate carrée projection. (BUY ARTWORK)
Star chart of the first 12,000,000 digits of $\pi$. The 80 constellations honor extinct animals and plants. Azimuthal equidistant projection. (BUY ARTWORK)
Star chart of the first 12,000,000 digits of $\pi$. The 80 constellations honor extinct animals and plants. Hammer/Aitoff elliptical projection. (BUY ARTWORK)

sepia

Star chart of the first 12,000,000 digits of $\pi$. The 80 constellations honor extinct animals and plants. Plate carrée projection. (BUY ARTWORK)
Star chart of the first 12,000,000 digits of $\pi$. The 80 constellations honor extinct animals and plants. Azimuthal equidistant projection. (BUY ARTWORK)
Star chart of the first 12,000,000 digits of $\pi$. The 80 constellations honor extinct animals and plants. Hammer/Aitoff elliptical projection. (BUY ARTWORK)
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Optimal experimental design

Tue 31-07-2018
Customize the experiment for the setting instead of adjusting the setting to fit a classical design.

The presence of constraints in experiments, such as sample size restrictions, awkward blocking or disallowed treatment combinations may make using classical designs very difficult or impossible.

Optimal design is a powerful, general purpose alternative for high quality, statistically grounded designs under nonstandard conditions.

Nature Methods Points of Significance column: Optimal experimental design. (read)

We discuss two types of optimal designs (D-optimal and I-optimal) and show how it can be applied to a scenario with sample size and blocking constraints.

Smucker, B., Krzywinski, M. & Altman, N. (2018) Points of significance: Optimal experimental design Nature Methods 15:599–600.

Krzywinski, M., Altman, N. (2014) Points of significance: Two factor designs. Nature Methods 11:1187–1188.

Krzywinski, M. & Altman, N. (2014) Points of significance: Analysis of variance (ANOVA) and blocking. Nature Methods 11:699–700.

Krzywinski, M. & Altman, N. (2014) Points of significance: Designing comparative experiments. Nature Methods 11:597–598.

The Whole Earth Cataloguer

Mon 30-07-2018
All the living things.

An illustration of the Tree of Life, showing some of the key branches.

The tree is drawn as a DNA double helix, with bases colored to encode ribosomal RNA genes from various organisms on the tree.

The circle of life. (read, zoom)

All living things on earth descended from a single organism called LUCA (last universal common ancestor) and inherited LUCA’s genetic code for basic biological functions, such as translating DNA and creating proteins. Constant genetic mutations shuffled and altered this inheritance and added new genetic material—a process that created the diversity of life we see today. The “tree of life” organizes all organisms based on the extent of shuffling and alteration between them. The full tree has millions of branches and every living organism has its own place at one of the leaves in the tree. The simplified tree shown here depicts all three kingdoms of life: bacteria, archaebacteria and eukaryota. For some organisms a grey bar shows when they first appeared in the tree in millions of years (Ma). The double helix winding around the tree encodes highly conserved ribosomal RNA genes from various organisms.

Johnson, H.L. (2018) The Whole Earth Cataloguer, Sactown, Jun/Jul, p. 89

Why we can't give up this odd way of typing

Mon 30-07-2018
All fingers report to home row.

An article about keyboard layouts and the history and persistence of QWERTY.

My Carpalx keyboard optimization software is mentioned along with my World's Most Difficult Layout: TNWMLC. True typing hell.

TNWMLC requires seriously flexible digits. It’s 87% more difficult than using a standard Qwerty keyboard, according to Martin Krzywinski, who created it (Credit: Ben Nelms). (read)

McDonald, T. (2018) Why we can't give up this odd way of typing, BBC, 25 May 2018.

Molecular Case Studies Cover

Fri 06-07-2018

The theme of the April issue of Molecular Case Studies is precision oncogenomics. We have three papers in the issue based on work done in our Personalized Oncogenomics Program (POG).

The covers of Molecular Case Studies typically show microscopy images, with some shown in a more abstract fashion. There's also the occasional Circos plot.

I've previously taken a more fine-art approach to cover design, such for those of Nature, Genome Research and Trends in Genetics. I've used microscopy images to create a cover for PNAS—the one that made biology look like astrophysics—and thought that this is kind of material I'd start with for the MCS cover.

Cover design for Apr 2018 issue of Molecular Case Studies. (details)

Happy 2018 $\tau$ Day—Art for everyone

Wed 27-06-2018
You know what day it is. (details)

Universe Superclusters and Voids

Mon 25-06-2018

A map of the nearby superclusters and voids in the Unvierse.

By "nearby" I mean within 6,000 million light-years.

The Universe — Superclustesr and Voids. The two supergalactic hemispheres showing Abell clusters, superclusters and voids within a distance of 6,000 million light-years from the Milky Way. (details)