Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca - contact me Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca on Twitter Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca - Lumondo Photography Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca - Pi Art Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca - Hilbertonians - Creatures on the Hilbert CurveMartin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca - Pi Day 2020 - Piku
Lips that taste of tears, they say, are the best for kissing.Dorothy Parkerget crankymore quotes

feynman point: fun


Scientific graphical abstracts — design guidelines


visualization + design

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
A `\pi` day music video!: Transcendental Tree Map premieres on 2020 Pi Day from Max Cooper's Yearning for the Infinite. Animation by Nick Cobby and myself. Watch live from Barbican Centre.
Music video of the “Transcendental Tree Map” Max Cooper's Yearning for the Infinite album. This video premiered on 2020 Pi Day. Music by Max Cooper. Animation by Nick Cobby and myself.
Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
The 2020 Pi Day art celebrates digits of `\pi` with piku (パイク) —poetry inspired by haiku.
They serve as the form for The Outbreak Poems.
Tau Day tree map animation of 8,909 digits of `\tau = 2 \pi` created with 40,015 lines. The video is 6:28 minutes long.

`\pi` Day 2014 Art Posters


Pi Day 2014 Art Poster - Folding the Number Pi
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2019 `\pi` has hundreds of digits, hundreds of languages and a special kids' edition.

Pi Day 2014 Art Poster - Folding the Number Pi
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2018 `\pi` day

Pi Day 2014 Art Poster - Folding the Number Pi
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2017 `\pi` day

Pi Day 2014 Art Poster - Folding the Number Pi
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2016 `\pi` approximation day

Pi Day 2014 Art Poster - Folding the Number Pi
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2016 `\pi` day

Pi Day 2014 Art Poster - Folding the Number Pi
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2015 `\pi` day

Pi Day 2014 Art Poster - Folding the Number Pi
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2014 `\pi` approx day

Pi Day 2014 Art Poster - Folding the Number Pi
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2014 `\pi` day

Pi Day 2014 Art Poster - Folding the Number Pi
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2013 `\pi` day

Pi Day 2014 Art Poster - Folding the Number Pi
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Circular `\pi` art

On March 14th celebrate `\pi` Day. Hug `\pi`—find a way to do it.

For those who favour `\tau=2\pi` will have to postpone celebrations until July 26th. That's what you get for thinking that `\pi` is wrong. I sympathize with this position and have `\tau` day art too!

If you're not into details, you may opt to party on July 22nd, which is `\pi` approximation day (`\pi` ≈ 22/7). It's 20% more accurate that the official `\pi` day!

Finally, if you believe that `\pi = 3`, you should read why `\pi` is not equal to 3.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
All art posters are available for purchase.
I take custom requests.

For the 2014 `\pi` day, two styles of posters are available: folded paths and frequency circles.

The folded paths show `\pi` on a path that maximizes adjacent prime digits and were created using a protein-folding algorithm.

The frequency circles colourfully depict the ratio of digits in groupings of 3 or 6. Oh, look, there's the Feynman Point!


Pi Day 2014 Art Poster - Folding the Number Pi
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Pi Day 2014 poster | Frequency distribution of digits in Pi for each of 128 6-digit groupings in 10 columns up to the Feynman Point. For each grouping the number of times a digit was seen is proportional to the width of the annulus. (zoom, BUY ARTWORK)

Pi Day 2014 Art Poster - Folding the Number Pi
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Pi Day 2014 poster | Frequency distribution of digits in Pi for each of 128 3-digit groupings in 12 columns up to the Feynman Point. For each grouping the number of times a digit was seen is proportional to the width of the annulus. (zoom, BUY ARTWORK)

Pi Day 2014 Art Poster - Folding the Number Pi
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Pi Day 2014 poster | Frequency distribution of digits in Pi for each of 128 3-digit groupings in 16 columns up to the Feynman Point. For each grouping the number of times a digit was seen is proportional to the width of the annulus. This is a very satisfying square layout. (zoom, BUY ARTWORK)

Pi Day 2014 Art Poster - Folding the Number Pi
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Pi Day 2014 poster | Frequency distribution of digits in Pi for each of 128 3-digit groupings in 16 columns up to the Feynman Point, with the first digit (3) offset to the top left. For each grouping the number of times a digit was seen is proportional to the width of the annulus. This is a very satisfying square layout. (zoom, BUY ARTWORK)

Pi Day 2014 Art Poster - Folding the Number Pi
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Pi Day 2014 poster | Frequency distribution of digits in Pi for the first 4,988 digits of Pi in groupings of 4. This subset contains the triplets for each digit, the last being 888 at digit 4,985. The layout is 29 columns and 43 rows. The first digit (3) offset to the top left. For each grouping the number of times a digit was seen is proportional to the width of the annulus. The Feynman Point 4(999999)8 is found in the middle of row 7. (zoom, BUY ARTWORK)

Pi Day 2014 Art Poster - Folding the Number Pi
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Pi Day 2014 poster | Frequency distribution of digits in Pi for the first 4,988 digits of Pi in groupings of 4. This subset contains the triplets for each digit, the last being 888 at digit 4,985. The layout is on an Archimedean spiral, with the the first digit (3) in the center. For each grouping the number of times a digit was seen is proportional to the width of the annulus. (zoom, BUY ARTWORK)

Pi Day 2014 Art Poster - Folding the Number Pi
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Pi Day 2014 poster | Frequency distribution of digits in Pi for the first 4,988 digits of Pi in groupings of 4. This subset contains the triplets for each digit, the last being 888 at digit 4,985. The layout is on an Archimedean spiral. For each grouping the number of times a digit was seen is proportional to the width of the annulus. (zoom, BUY ARTWORK)

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news + thoughts

Graphical Abstract Design Guidelines

Fri 13-11-2020

Clear, concise, legible and compelling.

Making a scientific graphical abstract? Refer to my practical design guidelines and redesign examples to improve organization, design and clarity of your graphical abstracts.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Graphical Abstract Design Guidelines — Clear, concise, legible and compelling.

"This data might give you a migrane"

Tue 06-10-2020

An in-depth look at my process of reacting to a bad figure — how I design a poster and tell data stories.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
A poster of high BMI and obesity prevalence for 185 countries.

He said, he said — a word analysis of the 2020 Presidential Debates

Thu 01-10-2020

Building on the method I used to analyze the 2008, 2012 and 2016 U.S. Presidential and Vice Presidential debates, I explore word usagein the 2020 Debates between Donald Trump and Joe Biden.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Analysis of word usage by parts of speech for Trump and Biden reveals insight into each candidate.

Points of Significance celebrates 50th column

Mon 24-08-2020

We are celebrating the publication of our 50th column!

To all our coauthors — thank you and see you in the next column!

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance: Celebrating 50 columns of clear explanations of statistics. (read)

Uncertainty and the management of epidemics

Mon 24-08-2020

When modelling epidemics, some uncertainties matter more than others.

Public health policy is always hampered by uncertainty. During a novel outbreak, nearly everything will be uncertain: the mode of transmission, the duration and population variability of latency, infection and protective immunity and, critically, whether the outbreak will fade out or turn into a major epidemic.

The uncertainty may be structural (which model?), parametric (what is `R_0`?), and/or operational (how well do masks work?).

This month, we continue our exploration of epidemiological models and look at how uncertainty affects forecasts of disease dynamics and optimization of intervention strategies.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Uncertainty and the management of epidemics. (read)

We show how the impact of the uncertainty on any choice in strategy can be expressed using the Expected Value of Perfect Information (EVPI), which is the potential improvement in outcomes that could be obtained if the uncertainty is resolved before making a decision on the intervention strategy. In other words, by how much could we potentially increase effectiveness of our choice (e.g. lowering total disease burden) if we knew which model best reflects reality?

This column has an interactive supplemental component (download code) that allows you to explore the impact of uncertainty in `R_0` and immunity duration on timing and size of epidemic waves and the total burden of the outbreak and calculate EVPI for various outbreak models and scenarios.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Uncertainty and the management of epidemics. (Interactive supplemental materials)

Bjørnstad, O.N., Shea, K., Krzywinski, M. & Altman, N. (2020) Points of significance: Uncertainty and the management of epidemics. Nature Methods 17.

Background reading

Bjørnstad, O.N., Shea, K., Krzywinski, M. & Altman, N. (2020) Points of significance: Modeling infectious epidemics. Nature Methods 17:455–456.

Bjørnstad, O.N., Shea, K., Krzywinski, M. & Altman, N. (2020) Points of significance: The SEIRS model for infectious disease dynamics. Nature Methods 17:557–558.

Cover of Nature Genetics August 2020

Mon 03-08-2020

Our design on the cover of Nature Genetics's August 2020 issue is “Dichotomy of Chromatin in Color” . Thanks to Dr. Andy Mungall for suggesting this terrific title.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Dichotomy of Chromatin in Color. Nature Genetics, August 2020 issue. (read more)

The cover design accompanies our report in the issue Gagliardi, A., Porter, V.L., Zong, Z. et al. (2020) Analysis of Ugandan cervical carcinomas identifies human papillomavirus clade–specific epigenome and transcriptome landscapes. Nature Genetics 52:800–810.