Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - contact me Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca on Twitter Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Lumondo Photography Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Pi Art Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Hilbertonians - Creatures on the Hilbert Curve
syncopation & accordionCafe de Flore (Doctor Rockit)like France, but no dog poopmore quotes

gravity: beautiful


DNA on 10th — street art, wayfinding and font


visualization + design

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
The 2019 Pi Day art celebrates digits of `\pi` with hundreds of languages and alphabets. If you're a kid at heart—rejoice—there's a special edition for you!

`\pi` Day 2016 Art Posters


Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2019 `\pi` has hundreds of digits, hundreds of languages and a special kids' edition.

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2018 `\pi` day

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2017 `\pi` day

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2016 `\pi` approximation day

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2016 `\pi` day

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2015 `\pi` day

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2014 `\pi` approx day

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2014 `\pi` day

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2013 `\pi` day

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Circular `\pi` art

On March 14th celebrate `\pi` Day. Hug `\pi`—find a way to do it.

For those who favour `\tau=2\pi` will have to postpone celebrations until July 26th. That's what you get for thinking that `\pi` is wrong. I sympathize with this position and have `\tau` day art too!

If you're not into details, you may opt to party on July 22nd, which is `\pi` approximation day (`\pi` ≈ 22/7). It's 20% more accurate that the official `\pi` day!

Finally, if you believe that `\pi = 3`, you should read why `\pi` is not equal to 3.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
All art posters are available for purchase.
I take custom requests.

This year's `\pi` day art collection celebrates not only the digit but also one of the fundamental forces in nature: gravity.

In February of 2016, for the first time, gravitational waves were detected at the Laser Interferometer Gravitational-Wave Observatory (LIGO).

The signal in the detector was sonified—a process by which any data can be encoded into sound to provide hints at patterns and structure that we might otherwise miss—and we finally heard what two black holes sound like. A buzz and chirp.

The art is featured in the Gravity of Pi article on the Scientific American SA Visual blog.

this year's theme music

All the art was processed while listening to Roses by Coeur de Pirate, a brilliant female French-Canadian songwriter, who sounds like a mix of Patricia Kaas and Lhasa. The lyrics Oublie-moi (Forget me) are fitting with this year's theme of gravity.

Mais laisse-moi tomber, laisse-nous tomber
Laisse la nuit trembler en moi
Laisse-moi tomber, laisse nous tomber
Cette fois

But let me fall, let us fall
Let the night tremble in me
Let me fall, let us fall
This time


Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
5 digits of `\pi`. (zoom, BUY ARTWORK)

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
5 digits of `\pi`. (zoom, BUY ARTWORK)

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
14 digits of `\pi`. (zoom, BUY ARTWORK)

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
14 digits of `\pi`. (zoom, BUY ARTWORK)

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
14 digits of `\pi`. (zoom, BUY ARTWORK)

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
44 digits of `\pi`. (zoom, BUY ARTWORK)

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
56 digits of `\pi`. (zoom, BUY ARTWORK)

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
65 digits of `\pi`. (zoom, BUY ARTWORK)

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
98 digits of `\pi`. (zoom, BUY ARTWORK)

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
153 digits of `\pi`. (zoom, BUY ARTWORK)

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
147 digits of `\pi`. (zoom, BUY ARTWORK)

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
335 digits of `\pi`. (zoom, BUY ARTWORK)

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
1,000 digits of `\pi`. (zoom, BUY ARTWORK)

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
1,000 digits of `\pi`. (zoom, BUY ARTWORK)

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
300 digits of `\pi`, `\phi` and `e`. (zoom, BUY ARTWORK)

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
100 digits of `\pi`, `\phi` and `e`. (zoom, BUY ARTWORK)

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
49 instances of 3 digits of `\pi`. (zoom, BUY ARTWORK)

Pi Day 2016 Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
49 instances of 3 digits of `\pi`. (zoom, BUY ARTWORK)
VIEW ALL

news + thoughts

Analyzing outliers: Robust methods to the rescue

Sat 30-03-2019
Robust regression generates more reliable estimates by detecting and downweighting outliers.

Outliers can degrade the fit of linear regression models when the estimation is performed using the ordinary least squares. The impact of outliers can be mitigated with methods that provide robust inference and greater reliability in the presence of anomalous values.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Analyzing outliers: Robust methods to the rescue. (read)

We discuss MM-estimation and show how it can be used to keep your fitting sane and reliable.

Greco, L., Luta, G., Krzywinski, M. & Altman, N. (2019) Points of significance: Analyzing outliers: Robust methods to the rescue. Nature Methods 16:275–276.

Background reading

Altman, N. & Krzywinski, M. (2016) Points of significance: Analyzing outliers: Influential or nuisance. Nature Methods 13:281–282.

Two-level factorial experiments

Fri 22-03-2019
To find which experimental factors have an effect, simultaneously examine the difference between the high and low levels of each.

Two-level factorial experiments, in which all combinations of multiple factor levels are used, efficiently estimate factor effects and detect interactions—desirable statistical qualities that can provide deep insight into a system.

They offer two benefits over the widely used one-factor-at-a-time (OFAT) experiments: efficiency and ability to detect interactions.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Two-level factorial experiments. (read)

Since the number of factor combinations can quickly increase, one approach is to model only some of the factorial effects using empirically-validated assumptions of effect sparsity and effect hierarchy. Effect sparsity tells us that in factorial experiments most of the factorial terms are likely to be unimportant. Effect hierarchy tells us that low-order terms (e.g. main effects) tend to be larger than higher-order terms (e.g. two-factor or three-factor interactions).

Smucker, B., Krzywinski, M. & Altman, N. (2019) Points of significance: Two-level factorial experiments Nature Methods 16:211–212.

Background reading

Krzywinski, M. & Altman, N. (2014) Points of significance: Designing comparative experiments.. Nature Methods 11:597–598.

Happy 2019 `\pi` Day—
Digits, internationally

Tue 12-03-2019

Celebrate `\pi` Day (March 14th) and set out on an exploration explore accents unknown (to you)!

This year is purely typographical, with something for everyone. Hundreds of digits and hundreds of languages.

A special kids' edition merges math with color and fat fonts.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
116 digits in 64 languages. (details)
Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
223 digits in 102 languages. (details)

Check out art from previous years: 2013 `\pi` Day and 2014 `\pi` Day, 2015 `\pi` Day, 2016 `\pi` Day, 2017 `\pi` Day and 2018 `\pi` Day.

Tree of Emotional Life

Sun 17-02-2019

One moment you're :) and the next you're :-.

Make sense of it all with my Tree of Emotional life—a hierarchical account of how we feel.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
A section of the Tree of Emotional Life.

Find and snap to colors in an image

Sat 29-12-2018

One of my color tools, the colorsnap application snaps colors in an image to a set of reference colors and reports their proportion.

Below is Times Square rendered using the colors of the MTA subway lines.


Colors used by the New York MTA subway lines.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Times Square in New York City.
Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Times Square in New York City rendered using colors of the MTA subway lines.
Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Granger rainbow snapped to subway lines colors from four cities. (zoom)

Take your medicine ... now

Wed 19-12-2018

Drugs could be more effective if taken when the genetic proteins they target are most active.

Design tip: rediscover CMYK primaries.

More of my American Scientific Graphic Science designs

Ruben et al. A database of tissue-specific rhythmically expressed human genes has potential applications in circadian medicine Science Translational Medicine 10 Issue 458, eaat8806.