Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - contact me Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca on Twitter Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Lumondo Photography Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Pi Art Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Hilbertonians - Creatures on the Hilbert Curve
And she looks like the moon. So close and yet, so far.Future Islandsaim highmore quotes

pi: exciting


DNA on 10th — street art, wayfinding and font


visualization + design

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
The 2019 Pi Day art celebrates digits of `\pi` with hundreds of languages and alphabets. If you're a kid at heart—rejoice—there's a special edition for you!

`pi` Day 2013 Art Posters


Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2019 `\pi` has hundreds of digits, hundreds of languages and a special kids' edition.

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2018 `\pi` day

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2017 `\pi` day

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2016 `\pi` approximation day

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2016 `\pi` day

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2015 `\pi` day

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2014 `\pi` approx day

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2014 `\pi` day

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
2013 `\pi` day

Pi Art Posters
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Circular `\pi` art

On March 14th celebrate `\pi` Day. Hug `\pi`—find a way to do it.

For those who favour `\tau=2\pi` will have to postpone celebrations until July 26th. That's what you get for thinking that `\pi` is wrong. I sympathize with this position and have `\tau` day art too!

If you're not into details, you may opt to party on July 22nd, which is `\pi` approximation day (`\pi` ≈ 22/7). It's 20% more accurate that the official `\pi` day!

Finally, if you believe that `\pi = 3`, you should read why `\pi` is not equal to 3.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
All art posters are available for purchase.
I take custom requests.

2013 was the first year in which I made `\pi` day art. It was a year of dots and love.

René Hansen has created an interactive version of this year's posters! Why not go to the Feynman point directly!

All the posters are also available without the "`\pi` day 3 · 14" inscription.

Pi Day Art Poster / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
768 digits of `\pi` up to the Feyman point. (PNG, BUY ARTWORK)
Pi Day Art Poster / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
768 digits of `\pi`, up to the Feyman point (left), `e` (middle) and `\phi` (right). (PNG, BUY ARTWORK)
Pi Day Art Poster / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
768 digits of `\pi`, up to the Feyman point (left), `e` (middle) and `\phi` (right). (PNG, BUY ARTWORK)

700 digits (20 x 35)

`\pi_i` / grey 80% opacity

Pi Day Art Poster / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Pi Day Art | March 14th is Pi Day. Celebrate with this post-modern poster. (PNG, BUY ARTWORK)

`\pi_i`/`\pi_{i+1}` 80% opacity

Pi Day Art Poster / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Pi Day Art | March 14th is Pi Day. Celebrate with this post-modern poster. (PNG, BUY ARTWORK)

2,800 (40 x 70) digits

`\pi_i` / grey 80% opacity (equal neighbours connected)

Pi Day Art Poster / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Pi Day Art | March 14th is Pi Day. Celebrate with this post-modern poster. (PNG, BUY ARTWORK)

`\pi_i` / `\pi_{i+1}` 80% opacity (equal neighbours connected)

Pi Day Art Poster / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Pi Day Art | March 14th is Pi Day. Celebrate with this post-modern poster. (PNG, BUY ARTWORK)

— / `\pi_{i+1}` (equal neighbours connected, unconnected digits not shown)

Pi Day Art Poster / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Pi Day Art | March 14th is Pi Day. Celebrate with this post-modern poster. (PNG, BUY ARTWORK)

`\pi_i` / `\pi_{i+1}` (equal neighbours connected with line width proportional to difference in neighbour digits `d in \{0,1,2\}`, unconnected digits not shown)

Pi Day Art Poster / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Pi Day Art | March 14th is Pi Day. Celebrate with this post-modern poster. (PNG, BUY ARTWORK)

`\pi_i` / `\pi_{i+1}` (equal neighbours connected with line width proportional to difference in neighbour digits `d in \{0...5\}`, unconnected digits not shown)

Pi Day Art Poster / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Pi Day Art | March 14th is Pi Day. Celebrate with this post-modern poster. (PNG, BUY ARTWORK)

`\pi` : — / red (equal neighbours connected, unconnected digits not shown)
`\phi` : — / white (equal neighbours connected, unconnected digits not shown)
`e` : — / grey (equal neighbours connected, unconnected digits not shown)

Pi Day Art Poster / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Pi Day Art | March 14th is Pi Day. Celebrate with this post-modern poster. (PNG, BUY ARTWORK)

11,400 (80 x 140) digits

`\pi_i` / grey 80% opacity (equal neighbours connected)

Pi Day Art Poster / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Pi Day Art | March 14th is Pi Day. Celebrate with this post-modern poster. (PNG, BUY ARTWORK)

`\pi_i` / `\pi_{i+1}` 80% opacity (equal neighbours connected)

Pi Day Art Poster / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Pi Day Art | March 14th is Pi Day. Celebrate with this post-modern poster. (PNG, BUY ARTWORK)

`\pi_i` / grey 80% opacity (equal neighbours connected, unconnected digits not shown)

Pi Day Art Poster / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Pi Day Art | March 14th is Pi Day. Celebrate with this post-modern poster. (PNG, BUY ARTWORK)

`\pi_i` / `\pi_{i+1}` 80% opacity (equal neighbours connected, unconnected digits not shown)

Pi Day Art Poster / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Pi Day Art | March 14th is Pi Day. Celebrate with this post-modern poster. (PNG, BUY ARTWORK)

love in `\pi`

Pi Day Art Poster / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Pi Day Art | March 14th is Pi Day. Celebrate with this post-modern poster. (PNG, BUY ARTWORK)
Pi Day Art Poster / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Pi Day Art | March 14th is Pi Day. Celebrate with this post-modern poster. (PNG, BUY ARTWORK)
Pi Day Art Poster / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Pi Day Art | March 14th is Pi Day. Celebrate with this post-modern poster. (PNG, BUY ARTWORK)

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news + thoughts

Analyzing outliers: Robust methods to the rescue

Sat 30-03-2019
Robust regression generates more reliable estimates by detecting and downweighting outliers.

Outliers can degrade the fit of linear regression models when the estimation is performed using the ordinary least squares. The impact of outliers can be mitigated with methods that provide robust inference and greater reliability in the presence of anomalous values.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Analyzing outliers: Robust methods to the rescue. (read)

We discuss MM-estimation and show how it can be used to keep your fitting sane and reliable.

Greco, L., Luta, G., Krzywinski, M. & Altman, N. (2019) Points of significance: Analyzing outliers: Robust methods to the rescue. Nature Methods 16:275–276.

Background reading

Altman, N. & Krzywinski, M. (2016) Points of significance: Analyzing outliers: Influential or nuisance. Nature Methods 13:281–282.

Two-level factorial experiments

Fri 22-03-2019
To find which experimental factors have an effect, simultaneously examine the difference between the high and low levels of each.

Two-level factorial experiments, in which all combinations of multiple factor levels are used, efficiently estimate factor effects and detect interactions—desirable statistical qualities that can provide deep insight into a system.

They offer two benefits over the widely used one-factor-at-a-time (OFAT) experiments: efficiency and ability to detect interactions.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Two-level factorial experiments. (read)

Since the number of factor combinations can quickly increase, one approach is to model only some of the factorial effects using empirically-validated assumptions of effect sparsity and effect hierarchy. Effect sparsity tells us that in factorial experiments most of the factorial terms are likely to be unimportant. Effect hierarchy tells us that low-order terms (e.g. main effects) tend to be larger than higher-order terms (e.g. two-factor or three-factor interactions).

Smucker, B., Krzywinski, M. & Altman, N. (2019) Points of significance: Two-level factorial experiments Nature Methods 16:211–212.

Background reading

Krzywinski, M. & Altman, N. (2014) Points of significance: Designing comparative experiments.. Nature Methods 11:597–598.

Happy 2019 `\pi` Day—
Digits, internationally

Tue 12-03-2019

Celebrate `\pi` Day (March 14th) and set out on an exploration explore accents unknown (to you)!

This year is purely typographical, with something for everyone. Hundreds of digits and hundreds of languages.

A special kids' edition merges math with color and fat fonts.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
116 digits in 64 languages. (details)
Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
223 digits in 102 languages. (details)

Check out art from previous years: 2013 `\pi` Day and 2014 `\pi` Day, 2015 `\pi` Day, 2016 `\pi` Day, 2017 `\pi` Day and 2018 `\pi` Day.

Tree of Emotional Life

Sun 17-02-2019

One moment you're :) and the next you're :-.

Make sense of it all with my Tree of Emotional life—a hierarchical account of how we feel.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
A section of the Tree of Emotional Life.

Find and snap to colors in an image

Sat 29-12-2018

One of my color tools, the colorsnap application snaps colors in an image to a set of reference colors and reports their proportion.

Below is Times Square rendered using the colors of the MTA subway lines.


Colors used by the New York MTA subway lines.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Times Square in New York City.
Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Times Square in New York City rendered using colors of the MTA subway lines.
Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Granger rainbow snapped to subway lines colors from four cities. (zoom)

Take your medicine ... now

Wed 19-12-2018

Drugs could be more effective if taken when the genetic proteins they target are most active.

Design tip: rediscover CMYK primaries.

More of my American Scientific Graphic Science designs

Ruben et al. A database of tissue-specific rhythmically expressed human genes has potential applications in circadian medicine Science Translational Medicine 10 Issue 458, eaat8806.