Twenty — minutes — maybe — more.choose four wordsmore quotes

# poetry: fun

EMBO Practical Course: Bioinformatics and Genome Analysis, 5–17 June 2017.

# daily quotation server archives

In the late 90’s I started (a good decade for starts) a daily quotation server project at www.quoteserver.ca. The domain is now defunct—some pages are partially viewable at the Way Back Machine.

Below is the list of quotes I had collected by the end of the life of the project. Most are about love—duh—and a few are jolly jests from funny trenches. You know, that place where mustard gas makes your eyes water.

The quotes weren’t scraped from quote archives—each is meaningful and hand-picked.

## the quote archive

And now for full list of 1,600 other things worth reading. Such as everything Dorothy Parker has written and ... yes, even the Pinky and Brain quotes, which are a special kind of special.

Quote collections about love, heart, desire, life, death, god, mind, science.

Feeling lucky? Read 10 random quotes. Well, will you, punk?

21
Shall any gazer see with mortal eyes,
Or any seeker know by mortal mind?
Veil after veil will lift — but there must be
Veil upon veil behind.
The Light of Asia, VIII
36
The mind has a thousand eyes,
And the heart but one;
Yet the light of a whole life dies,
When love is done.
Light
166
I don’t mind sleeping on an empty stomach provided it isn’t my own.
286
All life is a struggle in the dark ... This dread and
darkness of the mind cannot be dispelled by the
sunbeams, the shining shafts of day, but only by
an understanding of the outward form and inner
workings of nature. And now to business,
I will explain ...
On the Nature of the Universe
345
Serious error.
All shortcuts have disappeared.
Screen. Mind. Both are blank.
390
Friendship is almost always the union of a part of one mind with a part of another; people are friends in spots.
414
And, while with silent, lifting mind I’ve trod
The high untrespassed sanctity of space,
Put out my hand, and touched the face of God.
437
A mind is like a parachute; it only works when it is open.
444
Tact is the ability to tell a man he has an open mind when he has a hole in his head.
450
Get your mind out of the gutter—it’s blocking my view.
488
In the beginner’s mind there are many possibilities, but in the expert’s mind there are a few.
612
There is a lady sweet and kind,
Was never a face so pleased my mind;
I did but see her passing by,
And yet I love her till I die.
617
With women the heart argues, not the mind.
Merope, 1.341
674
In every cry of every Man,
In every Infants cry of fear,
In every voice: in every ban,
The mind-forg’d manacles I hear.
London
696
Paracelsus, pt. iii, i.363
708
I do not mind lying but I hate inaccuracy.
Note Books
743
That out of sight is out of mind
Is true of most we leave behind.
Songs in Absence, That Out of Sight
866
Beauty in things exists in the mind which contemplates them.
Of Tragedy
871
Some experience of popular lecturing had convinced me that the necessity of making things plain to uninstructed people was one of the very best means of clearing up the obscure conrners in one’s own mind.
Man’s Place in Nature
965
A fanatic is one who can’t change his mind and won’t change the subject.
983
Dans les champs de l’observation le hasard ne favorise que les esprits prepares.
[Where observation is concerned, chance favours only the prepared mind.]
1137
Years steal
Fire from the mind as vigor from the limb,
And life’s enchanted cup but sparkles near the brim.
Childe Harold’s Pilgrimage
1182
This have I known always: Love is no more
Than the wide blossom which the wind assails,
Than the great tide that treads the shifting shore,
Strewing fresh wreckage gathered in the gales:
Pity me that the heart is slow to learn
What the swift mind beholds at every turn.
Sonnets, xxix
1195
I know a man that’s a braver man
And twenty men as kind,
And what are you, that you should be
The one man in my mind?
The Philosopher
1317
Her mind lives tidily, apart
From cold and noise and pain,
And bolts the door against her heart,
Out wailing in the rain.
Interior
1508
Nothing contributes so much to tranquilizing the mind as a steady purpose—a point on which the soul may fix its intellectual eye.
1547
So the old tunes float in my mind,
And go from me leaving no trace behind,
Like fragrance borne on the hush of the wind.
but in the instant the airs remain
I know the laughter and the pain
Of times that will not come again.
Old Tunes
1584
Remember me and beare in mind
A truthful friend is hard to find
The path of sorrow and that alone
Leads to a place where sorrow is unknown.
Autograph Albums and Bible of Ella Beaver Calhoun
1634
Something made of nothing, tasting very sweet,
A most delicious compound, with ingredients complete;
But if, as on occasion, the heart and mind are sour,
It has no great significance, and loses half its power.
The Kiss
VIEW ALL

# Snellen Charts—Typography to Really Look at

Sat 18-02-2017

Another collection of typographical posters. These ones really ask you to look.

Snellen charts designed using physical constants, Braille and elemental abundances in the universe and human body.

The charts show a variety of interesting symbols and operators found in science and math. The design is in the style of a Snellen chart and typset with the Rockwell font.

# Essentials of Data Visualization—8-part video series

Fri 17-02-2017

In collaboration with the Phil Poronnik and Kim Bell-Anderson at the University of Sydney, I'm delighted to share with you our 8-part video series project about thinking about drawing data and communicating science.

Essentials of Data Visualization: Thinking about drawing data and communicating science.

We've created 8 videos, each focusing on a different essential idea in data visualization: encoding, shapes, color, uncertainty, design, drawing missing or unobserved data, labels and process.

The videos were designed as teaching materials. Each video comes with a slide deck and exercises.

# P values and the search for significance

Mon 16-01-2017
Little P value
What are you trying to say
Of significance?
—Steve Ziliak

We've written about P values before and warned readers about common misconceptions about them, which are so rife that the American Statistical Association itself has a long statement about them.

This month is our first of a two-part article about P values. Here we look at 'P value hacking' and 'data dredging', which are questionable practices that invalidate the correct interpretation of P values.

Nature Methods Points of Significance column: P values and the search for significance. (read)

We also illustrate how P values can lead us astray by asking "What is the smallest P value we can expect if the null hypothesis is true but we have done many tests, either explicitly or implicitly?"

Incidentally, this is our first column in which the standfirst is a haiku.

Altman, N. & Krzywinski, M. (2017) Points of Significance: P values and the search for significance. Nature Methods 14:3–4.

Krzywinski, M. & Altman, N. (2013) Points of significance: Significance, P values and tâtests. Nature Methods 10:1041â1042.

# Intuitive Design

Thu 03-11-2016

Appeal to intuition when designing with value judgments in mind.

Figure clarity and concision are improved when the selection of shapes and colors is grounded in the Gestalt principles, which describe how we visually perceive and organize information.

One of the Gestalt principles tells us that the magenta and green shapes will be perceived as as two groups, overriding the fact that the shapes within the group might be different. What the principle does not tell us is how the reader is likely to value each group. (read)

The Gestalt principles are value free. For example, they tell us how we group objects but do not speak to any meaning that we might intuitively infer from visual characteristics.

Nature Methods Points of View column: Intuitive Design. (read)

This month, we discuss how appealing to such intuitions—related to shapes, colors and spatial orientation— can help us add information to a figure as well as anticipate and encourage useful interpretations.

Krzywinski, M. (2016) Points of View: Intuitive Design. Nature Methods 13:895.

# Regularization

Fri 04-11-2016

Constraining the magnitude of parameters of a model can control its complexity.

This month we continue our discussion about model selection and evaluation and address how to choose a model that avoids both overfitting and underfitting.

Ideally, we want to avoid having either an underfitted model, which is usually a poor fit to the training data, or an overfitted model, which is a good fit to the training data but not to new data.

Nature Methods Points of Significance column: Regularization (read)

Regularization is a process that penalizes the magnitude of model parameters. This is done by not only minimizing the SSE, $\mathrm{SSE} = \sum_i (y_i - \hat{y}_i)^2$, as is done normally in a fit, but adding to this minimized quantity the sum of the mode's squared parameters, $\mathrm{SSE} + \lambda \sum_i \hat{\beta}^2_i$.

Lever, J., Krzywinski, M. & Altman, N. (2016) Points of Significance: Regularization. Nature Methods 13:803-804.