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Poetry is just the evidence of life. If your life is burning well, poetry is just the ashLeonard Cohenburn somethingmore quotes

quotes: beautiful

EMBO Practical Course: Bioinformatics and Genome Analysis, 5–17 June 2017.

art + literature

daily quotation server archives

In the late 90’s I started (a good decade for starts) a daily quotation server project at The domain is now defunct—some pages are partially viewable at the Way Back Machine.

Below is the list of quotes I had collected by the end of the life of the project. Most are about love—duh—and a few are jolly jests from funny trenches. You know, that place where mustard gas makes your eyes water.

The quotes weren’t scraped from quote archives—each is meaningful and hand-picked.

the quote archive

And now for full list of 1,600 other things worth reading. Such as everything Dorothy Parker has written and ... yes, even the Pinky and Brain quotes, which are a special kind of special.

Quote collections about love, heart, desire, life, death, god, mind, science.

Feeling lucky? Read 10 random quotes. Well, will you, punk?

Quotes about mind

Shall any gazer see with mortal eyes,
Or any seeker know by mortal mind?
Veil after veil will lift — but there must be
Veil upon veil behind.
Sir Edwin Arnold
The Light of Asia, VIII
The mind has a thousand eyes,
And the heart but one;
Yet the light of a whole life dies,
When love is done.
Francis Bourdillon
I don’t mind sleeping on an empty stomach provided it isn’t my own.
Philip J. Simborg
All life is a struggle in the dark ... This dread and
darkness of the mind cannot be dispelled by the
sunbeams, the shining shafts of day, but only by
an understanding of the outward form and inner
workings of nature. And now to business,
I will explain ...
On the Nature of the Universe
Serious error.
All shortcuts have disappeared.
Screen. Mind. Both are blank.
A Haiku computer error message.
Friendship is almost always the union of a part of one mind with a part of another; people are friends in spots.
George Santayana
And, while with silent, lifting mind I’ve trod
The high untrespassed sanctity of space,
Put out my hand, and touched the face of God.
John Gillespie Magee, Jr.
A mind is like a parachute; it only works when it is open.
Sir James Dewar
Tact is the ability to tell a man he has an open mind when he has a hole in his head.
Get your mind out of the gutter—it’s blocking my view.
In the beginner’s mind there are many possibilities, but in the expert’s mind there are a few.
Shunryu Suzuki
There is a lady sweet and kind,
Was never a face so pleased my mind;
I did but see her passing by,
And yet I love her till I die.
With women the heart argues, not the mind.
Matthew Arnold
Merope, 1.341
In every cry of every Man,
In every Infants cry of fear,
In every voice: in every ban,
The mind-forg’d manacles I hear.
William Blake
Measure your mind’s height by the shade it casts.
Robert Browning
Paracelsus, pt. iii, i.363
I do not mind lying but I hate inaccuracy.
Samuel Butler
Note Books
That out of sight is out of mind
Is true of most we leave behind.
Arthur Hugh Clough
Songs in Absence, That Out of Sight
Beauty in things exists in the mind which contemplates them.
David Hume
Of Tragedy
Some experience of popular lecturing had convinced me that the necessity of making things plain to uninstructed people was one of the very best means of clearing up the obscure conrners in one’s own mind.
T.H. Huxley
Man’s Place in Nature
A fanatic is one who can’t change his mind and won’t change the subject.
Winston Churchill
Dans les champs de l’observation le hasard ne favorise que les esprits prepares.
[Where observation is concerned, chance favours only the prepared mind.]
Louis Pasteur
Years steal
Fire from the mind as vigor from the limb,
And life’s enchanted cup but sparkles near the brim.
Lord Byron
Childe Harold’s Pilgrimage
This have I known always: Love is no more
Than the wide blossom which the wind assails,
Than the great tide that treads the shifting shore,
Strewing fresh wreckage gathered in the gales:
Pity me that the heart is slow to learn
What the swift mind beholds at every turn.
Edna St. Vincent Millay
Sonnets, xxix
I know a man that’s a braver man
And twenty men as kind,
And what are you, that you should be
The one man in my mind?
Edna St. Vincent Millay
The Philosopher
Her mind lives tidily, apart
From cold and noise and pain,
And bolts the door against her heart,
Out wailing in the rain.
Dorothy Parker
Nothing contributes so much to tranquilizing the mind as a steady purpose—a point on which the soul may fix its intellectual eye.
Mary Wollstonecraft Shelley
So the old tunes float in my mind,
And go from me leaving no trace behind,
Like fragrance borne on the hush of the wind.
but in the instant the airs remain
I know the laughter and the pain
Of times that will not come again.
Sara Teasdale
Old Tunes
Remember me and beare in mind
A truthful friend is hard to find
The path of sorrow and that alone
Leads to a place where sorrow is unknown.
Anna Bowman
Autograph Albums and Bible of Ella Beaver Calhoun
Something made of nothing, tasting very sweet,
A most delicious compound, with ingredients complete;
But if, as on occasion, the heart and mind are sour,
It has no great significance, and loses half its power.
Mary. E. Buell
The Kiss

news + thoughts

What's wrong with pie charts?

Thu 25-05-2017

In this redesign of a pie chart figure from a Nature Medicine article [1], I look at how to organize and present a large number of categories.

I first discuss some of the benefits of a pie chart—there are few and specific—and its shortcomings—there are few but fundamental.

I then walk through the redesign process by showing how the tumor categories can be shown more clearly if they are first aggregated into a small number groups.

(bottom left) Figure 2b from Zehir et al. Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients. (2017) Nature Medicine doi:10.1038/nm.4333

Tabular Data

Tue 11-04-2017
Tabulating the number of objects in categories of interest dates back to the earliest records of commerce and population censuses.

After 30 columns, this is our first one without a single figure. Sometimes a table is all you need.

In this column, we discuss nominal categorical data, in which data points are assigned to categories in which there is no implied order. We introduce one-way and two-way tables and the `\chi^2` and Fisher's exact tests.

Altman, N. & Krzywinski, M. (2017) Points of Significance: Tabular data. Nature Methods 14:329–330.

...more about the Points of Significance column

Happy 2017 `\pi` Day—Star Charts, Creatures Once Living and a Poem

Tue 14-03-2017

on a brim of echo,

capsized chamber
drawn into our constellation, and cooling.
—Paolo Marcazzan

Celebrate `\pi` Day (March 14th) with star chart of the digits. The charts draw 40,000 stars generated from the first 12 million digits.

Martin Krzywinski @MKrzywinski
12,000,000 digits of `\pi` interpreted as a star catalogue. (details)

The 80 constellations are extinct animals and plants. Here you'll find old friends and new stories. Read about how Desmodus is always trying to escape or how Megalodon terrorizes the poor Tecopa! Most constellations have a story.

Martin Krzywinski @MKrzywinski
Find friends and stories among the 80 constellations of extinct animals and plants. Oh look, a Dodo guardings his eggs! (details)

This year I collaborate with Paolo Marcazzan, a Canadian poet, who contributes a poem, Of Black Body, about space and things we might find and lose there.

Check out art from previous years: 2013 `\pi` Day and 2014 `\pi` Day, 2015 `\pi` Day and and 2016 `\pi` Day.

Data in New Dimensions: convergence of art, genomics and bioinformatics

Tue 07-03-2017

Art is science in love.
— E.F. Weisslitz

A behind-the-scenes look at the making of our stereoscopic images which were at display at the AGBT 2017 Conference in February. The art is a creative collaboration with Becton Dickinson and The Linus Group.

Its creation began with the concept of differences and my writeup of the creative and design process focuses on storytelling and how concept of differences is incorporated into the art.

Oh, and this might be a good time to pick up some red-blue 3D glasses.

BD Genomics 3D art exhibit - AGBT 2017 / Martin Krzywinski @MKrzywinski
A stereoscopic image and its interpretive panel of single-cell transcriptomes of blood cells: diseased versus healthy control.

Interpreting P values

Thu 02-03-2017
A P value measures a sample’s compatibility with a hypothesis, not the truth of the hypothesis.

This month we continue our discussion about `P` values and focus on the fact that `P` value is a probability statement about the observed sample in the context of a hypothesis, not about the hypothesis being tested.

Martin Krzywinski @MKrzywinski
Nature Methods Points of Significance column: Interpreting P values. (read)

Given that we are always interested in making inferences about hypotheses, we discuss how `P` values can be used to do this by way of the Benjamin-Berger bound, `\bar{B}` on the Bayes factor, `B`.

Heuristics such as these are valuable in helping to interpret `P` values, though we stress that `P` values vary from sample to sample and hence many sources of evidence need to be examined before drawing scientific conclusions.

Altman, N. & Krzywinski, M. (2017) Points of Significance: Interpreting P values. Nature Methods 14:213–214.

Background reading

Krzywinski, M. & Altman, N. (2017) Points of significance: P values and the search for significance. Nature Methods 14:3–4.

Krzywinski, M. & Altman, N. (2013) Points of significance: Significance, P values and t–tests. Nature Methods 10:1041–1042.

...more about the Points of Significance column