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Sun is on my face ...a beautiful day without you.Royskoppbe apartmore quotes

english: fun

In Silico Flurries: Computing a world of snow. Scientific American. 23 December 2017

art + literature

daily quotation server archives

In the late 90’s I started (a good decade for starts) a daily quotation server project at The domain is now defunct—some pages are partially viewable at the Way Back Machine.

Below is the list of quotes I had collected by the end of the life of the project. Most are about love—duh—and a few are jolly jests from funny trenches. You know, that place where mustard gas makes your eyes water.

The quotes weren’t scraped from quote archives—each is meaningful and hand-picked.

the quote archive

And now for full list of 1,600 other things worth reading. Such as everything Dorothy Parker has written and ... yes, even the Pinky and Brain quotes, which are a special kind of special.

Quote collections about love, heart, desire, life, death, god, mind, science.

Feeling lucky? Read 10 random quotes. Well, will you, punk?

Quotes about mind

Shall any gazer see with mortal eyes,
Or any seeker know by mortal mind?
Veil after veil will lift — but there must be
Veil upon veil behind.
Sir Edwin Arnold
The Light of Asia, VIII
The mind has a thousand eyes,
And the heart but one;
Yet the light of a whole life dies,
When love is done.
Francis Bourdillon
I don’t mind sleeping on an empty stomach provided it isn’t my own.
Philip J. Simborg
All life is a struggle in the dark ... This dread and
darkness of the mind cannot be dispelled by the
sunbeams, the shining shafts of day, but only by
an understanding of the outward form and inner
workings of nature. And now to business,
I will explain ...
On the Nature of the Universe
Serious error.
All shortcuts have disappeared.
Screen. Mind. Both are blank.
A Haiku computer error message.
Friendship is almost always the union of a part of one mind with a part of another; people are friends in spots.
George Santayana
And, while with silent, lifting mind I’ve trod
The high untrespassed sanctity of space,
Put out my hand, and touched the face of God.
John Gillespie Magee, Jr.
A mind is like a parachute; it only works when it is open.
Sir James Dewar
Tact is the ability to tell a man he has an open mind when he has a hole in his head.
Get your mind out of the gutter—it’s blocking my view.
In the beginner’s mind there are many possibilities, but in the expert’s mind there are a few.
Shunryu Suzuki
There is a lady sweet and kind,
Was never a face so pleased my mind;
I did but see her passing by,
And yet I love her till I die.
With women the heart argues, not the mind.
Matthew Arnold
Merope, 1.341
In every cry of every Man,
In every Infants cry of fear,
In every voice: in every ban,
The mind-forg’d manacles I hear.
William Blake
Measure your mind’s height by the shade it casts.
Robert Browning
Paracelsus, pt. iii, i.363
I do not mind lying but I hate inaccuracy.
Samuel Butler
Note Books
That out of sight is out of mind
Is true of most we leave behind.
Arthur Hugh Clough
Songs in Absence, That Out of Sight
Beauty in things exists in the mind which contemplates them.
David Hume
Of Tragedy
Some experience of popular lecturing had convinced me that the necessity of making things plain to uninstructed people was one of the very best means of clearing up the obscure conrners in one’s own mind.
T.H. Huxley
Man’s Place in Nature
A fanatic is one who can’t change his mind and won’t change the subject.
Winston Churchill
Dans les champs de l’observation le hasard ne favorise que les esprits prepares.
[Where observation is concerned, chance favours only the prepared mind.]
Louis Pasteur
Years steal
Fire from the mind as vigor from the limb,
And life’s enchanted cup but sparkles near the brim.
Lord Byron
Childe Harold’s Pilgrimage
This have I known always: Love is no more
Than the wide blossom which the wind assails,
Than the great tide that treads the shifting shore,
Strewing fresh wreckage gathered in the gales:
Pity me that the heart is slow to learn
What the swift mind beholds at every turn.
Edna St. Vincent Millay
Sonnets, xxix
I know a man that’s a braver man
And twenty men as kind,
And what are you, that you should be
The one man in my mind?
Edna St. Vincent Millay
The Philosopher
Her mind lives tidily, apart
From cold and noise and pain,
And bolts the door against her heart,
Out wailing in the rain.
Dorothy Parker
Nothing contributes so much to tranquilizing the mind as a steady purpose—a point on which the soul may fix its intellectual eye.
Mary Wollstonecraft Shelley
So the old tunes float in my mind,
And go from me leaving no trace behind,
Like fragrance borne on the hush of the wind.
but in the instant the airs remain
I know the laughter and the pain
Of times that will not come again.
Sara Teasdale
Old Tunes
Remember me and beare in mind
A truthful friend is hard to find
The path of sorrow and that alone
Leads to a place where sorrow is unknown.
Anna Bowman
Autograph Albums and Bible of Ella Beaver Calhoun
Something made of nothing, tasting very sweet,
A most delicious compound, with ingredients complete;
But if, as on occasion, the heart and mind are sour,
It has no great significance, and loses half its power.
Mary. E. Buell
The Kiss

news + thoughts

Optimal experimental design

Tue 31-07-2018
Customize the experiment for the setting instead of adjusting the setting to fit a classical design.

The presence of constraints in experiments, such as sample size restrictions, awkward blocking or disallowed treatment combinations may make using classical designs very difficult or impossible.

Optimal design is a powerful, general purpose alternative for high quality, statistically grounded designs under nonstandard conditions.

Martin Krzywinski @MKrzywinski
Nature Methods Points of Significance column: Optimal experimental design. (read)

We discuss two types of optimal designs (D-optimal and I-optimal) and show how it can be applied to a scenario with sample size and blocking constraints.

Smucker, B., Krzywinski, M. & Altman, N. (2018) Points of significance: Optimal experimental design Nature Methods 15:599–600.

Background reading

Krzywinski, M., Altman, N. (2014) Points of significance: Two factor designs. Nature Methods 11:1187–1188.

Krzywinski, M. & Altman, N. (2014) Points of significance: Analysis of variance (ANOVA) and blocking. Nature Methods 11:699–700.

Krzywinski, M. & Altman, N. (2014) Points of significance: Designing comparative experiments. Nature Methods 11:597–598.

The Whole Earth Cataloguer

Mon 30-07-2018
All the living things.

An illustration of the Tree of Life, showing some of the key branches.

The tree is drawn as a DNA double helix, with bases colored to encode ribosomal RNA genes from various organisms on the tree.

Martin Krzywinski @MKrzywinski
The circle of life. (read, zoom)

All living things on earth descended from a single organism called LUCA (last universal common ancestor) and inherited LUCA’s genetic code for basic biological functions, such as translating DNA and creating proteins. Constant genetic mutations shuffled and altered this inheritance and added new genetic material—a process that created the diversity of life we see today. The “tree of life” organizes all organisms based on the extent of shuffling and alteration between them. The full tree has millions of branches and every living organism has its own place at one of the leaves in the tree. The simplified tree shown here depicts all three kingdoms of life: bacteria, archaebacteria and eukaryota. For some organisms a grey bar shows when they first appeared in the tree in millions of years (Ma). The double helix winding around the tree encodes highly conserved ribosomal RNA genes from various organisms.

Johnson, H.L. (2018) The Whole Earth Cataloguer, Sactown, Jun/Jul, p. 89

Why we can't give up this odd way of typing

Mon 30-07-2018
All fingers report to home row.

An article about keyboard layouts and the history and persistence of QWERTY.

My Carpalx keyboard optimization software is mentioned along with my World's Most Difficult Layout: TNWMLC. True typing hell.

Martin Krzywinski @MKrzywinski
TNWMLC requires seriously flexible digits. It’s 87% more difficult than using a standard Qwerty keyboard, according to Martin Krzywinski, who created it (Credit: Ben Nelms). (read)

McDonald, T. (2018) Why we can't give up this odd way of typing, BBC, 25 May 2018.

Molecular Case Studies Cover

Fri 06-07-2018

The theme of the April issue of Molecular Case Studies is precision oncogenomics. We have three papers in the issue based on work done in our Personalized Oncogenomics Program (POG).

The covers of Molecular Case Studies typically show microscopy images, with some shown in a more abstract fashion. There's also the occasional Circos plot.

I've previously taken a more fine-art approach to cover design, such for those of Nature, Genome Research and Trends in Genetics. I've used microscopy images to create a cover for PNAS—the one that made biology look like astrophysics—and thought that this is kind of material I'd start with for the MCS cover.

Martin Krzywinski @MKrzywinski
Cover design for Apr 2018 issue of Molecular Case Studies. (details)

Happy 2018 `\tau` Day—Art for everyone

Wed 27-06-2018
Martin Krzywinski @MKrzywinski
You know what day it is. (details)