Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - contact me Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca on Twitter Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Lumondo Photography Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Pi Art Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Hilbertonians - Creatures on the Hilbert Curve
Tango is a sad thought that is danced.Enrique Santos Discépolothink & dancemore quotes

words: exciting


DNA on 10th — street art, wayfinding and font


art + literature

daily quotation server archives

In the late 90’s I started (a good decade for starts) a daily quotation server project at www.quoteserver.ca. The domain is now defunct—some pages are partially viewable at the Way Back Machine.

Below is the list of quotes I had collected by the end of the life of the project. Most are about love—duh—and a few are jolly jests from funny trenches. You know, that place where mustard gas makes your eyes water.

The quotes weren’t scraped from quote archives—each is meaningful and hand-picked.

the quote archive

And now for full list of 1,600 other things worth reading. Such as everything Dorothy Parker has written and ... yes, even the Pinky and Brain quotes, which are a special kind of special.

Quote collections about love, heart, desire, life, death, god, mind, science.

Feeling lucky? Read 10 random quotes. Well, will you, punk?

Quotes about god

13
Take not God’s name in vain: select a time when it will have effect.
Ambrose Bierce
48
I love thee with the love I seemed to lose
With my lost saints,—I love thee with the breath
Smiles, tears, of all my life!—and, if God choose,
I shall but love thee better after death.
Elizabeth Barrett Browning
Sonnets from the Portuguese
104
Poems are made by fools like me,
But only God can make a tree.
Joyce Kilmer
Trees
117
All are but parts of one stupendous whole,
Whose body Nature is, and God the soul.
Alexander Pope
Essay on Man, Epistle i. 267.
243
Conceit is God’s gift to little men.
298
Poems are made by fools like me,
But only God can make a tree.
Joyce Kilmer
Trees
370
Men rarely (if ever) manage to dream up a god superior to themselves. Most gods have the manners and morals of a spoiled child.
Lazarus Long
Time Enough for Love
414
And, while with silent, lifting mind I’ve trod
The high untrespassed sanctity of space,
Put out my hand, and touched the face of God.
John Gillespie Magee, Jr.
452
God must love stupid people, He made so many of them.
457
If it turns out that there is a God, I don’t think that he’s evil. But the worst that you can say about him is that basically he’s an underachiever.
Woody Allen
556
% ar m God
ar: God does not exist
561
God made the integers; all else is the work of Man.
Kronecker
591
If you believe in the light, it’s because of obscurity.
If you believe in happiness it’s because of unhappiness.
If you believe in God, then you have to believe in the Devil.
Father X
Church of Notre Dame, Paris
609
O God, if there be a God, save my soul, if I have a soul!
611
See the happy moron,
He doesn’t give a damn.
I wish I were a moron.
My God! Perhaps I am!
706
An Apology for the Devil: It must be remembered that
we have only heard one side of the case. God has written
all the books.
Samuel Butler
Note Books
741
And almost every one when age,
Disease, or sorrows strike him,
Inclines to think there is a God,
Or something very like Him.
Arthur Hugh Clough
Dipsychus, sc. vi
783
So nigh is grandeur to our dust,
So near is God to man,
When Duty whispers low, Thou must,
The youth replies, I can.
Ralph Waldo Emerson
Voluntaries, iii
957
Gott ist tot: aber so wie die Art der Menschen ist,
wird es vielleicht noch jahrtausendlang Hohlen geben,
in denen man seinen Schatten zeigt.
[God is dead: but considering the state the species Man
is in, there will perhaps be caves, for ages yet, in which
his shadow will be shown.]
Friedrich Nietzsche
Ecce Homo
1082
O God! methinks it were a happy life,
To be no better than a homely swain;
To sit upon a hill, as I do now,
To carve out dials, quaintly, point by point,
Thereby to see the minutes how they run,
How many make the hour full complete;
How many hours bring about the day;
How many days will finish up the year;
How many years a mortal man may live.
William Shakespeare
Henry VII, Part III, II.v.21
1213
I loved you without hope, a mute offender;
What jealous pangs, what shy despairs I knew!
A love as deep as this, as true, as tender,
God grant another may yet offer you.
Alexander Pushkin
I Loved You Once
1218
I have heard the song of the blossoms and the old chant of the sea,
And seen strange lands from under the arched white sails of ships;
But the loveliest things of beauty God ever has showed to me,
Are her voice, and her hair, and eyes, and the dear red curve of her lips.
John Masefield
Beauty
1284
And this, O love, my pitiable plight
Whenever from my circling arms you stray;
This little world of mine has lost its light....
I hope to God, my dear, that you can say
The same to me.
Dorothy Parker
Rondeau Redouble
1333
How can I believe in God when just last week I got
my tongue caught in the roller of an electric typewriter?
Woody Allen
1334
Man is a god in ruins.
Ralph Waldo Emerson
1386
God made everything out of nothing, but the nothingness
shows through.
Paul Valery
1402
Which is it, is man one of God’s blunders or is
God one of man’s?
Friedrich Nietzsche
1416
Thank God men cannot as yet fly and lay waste the
sky as well as the earth!
Henry David Thoreau
1477
Nothing but blackness above
And nothing that moves but the cars...
God, if you wish for our love,
Fling us a handful of stars!
Louis Untermeyer
Caliban in the Coal Mines
1526
God is the immemorial refuge of the incompetent, the helpless, the miserable. They find not only sanctuary in His arms, but also a kind of superiority, soothing to their macerated egos; He will set them above their betters.
H.L. Mencken
1534
If the average man is made in God’s image, then a man such as Beethoven or Aristotle is plainly superior to God, and so God may be jealous of him, and eager to see his superiority perish with his bodily frame. All animal breeders know how difficult it is to maintain a fine strain. The universe seems to be in a conspiracy to encourage the endless reproduction of peasants and Socialists, but a subtle and mysterious opposition stands eternally against the reproduction of philosophers.
H.L. Mencken
In Defense of Women
1602
We turn toward God only to obtain the impossible.
Albert Camus
VIEW ALL

news + thoughts

Quantile regression

Sat 01-06-2019
Quantile regression robustly estimates the typical and extreme values of a response.

Quantile regression explores the effect of one or more predictors on quantiles of the response. It can answer questions such as "What is the weight of 90% of individuals of a given height?"

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Quantile regression. (read)

Unlike in traditional mean regression methods, no assumptions about the distribution of the response are required, which makes it practical, robust and amenable to skewed distributions.

Quantile regression is also very useful when extremes are interesting or when the response variance varies with the predictors.

Das, K., Krzywinski, M. & Altman, N. (2019) Points of significance: Quantile regression. Nature Methods 16:451–452.

Background reading

Altman, N. & Krzywinski, M. (2015) Points of significance: Simple linear regression. Nature Methods 12:999–1000.

Analyzing outliers: Robust methods to the rescue

Sat 30-03-2019
Robust regression generates more reliable estimates by detecting and downweighting outliers.

Outliers can degrade the fit of linear regression models when the estimation is performed using the ordinary least squares. The impact of outliers can be mitigated with methods that provide robust inference and greater reliability in the presence of anomalous values.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Analyzing outliers: Robust methods to the rescue. (read)

We discuss MM-estimation and show how it can be used to keep your fitting sane and reliable.

Greco, L., Luta, G., Krzywinski, M. & Altman, N. (2019) Points of significance: Analyzing outliers: Robust methods to the rescue. Nature Methods 16:275–276.

Background reading

Altman, N. & Krzywinski, M. (2016) Points of significance: Analyzing outliers: Influential or nuisance. Nature Methods 13:281–282.

Two-level factorial experiments

Fri 22-03-2019
To find which experimental factors have an effect, simultaneously examine the difference between the high and low levels of each.

Two-level factorial experiments, in which all combinations of multiple factor levels are used, efficiently estimate factor effects and detect interactions—desirable statistical qualities that can provide deep insight into a system.

They offer two benefits over the widely used one-factor-at-a-time (OFAT) experiments: efficiency and ability to detect interactions.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Two-level factorial experiments. (read)

Since the number of factor combinations can quickly increase, one approach is to model only some of the factorial effects using empirically-validated assumptions of effect sparsity and effect hierarchy. Effect sparsity tells us that in factorial experiments most of the factorial terms are likely to be unimportant. Effect hierarchy tells us that low-order terms (e.g. main effects) tend to be larger than higher-order terms (e.g. two-factor or three-factor interactions).

Smucker, B., Krzywinski, M. & Altman, N. (2019) Points of significance: Two-level factorial experiments Nature Methods 16:211–212.

Background reading

Krzywinski, M. & Altman, N. (2014) Points of significance: Designing comparative experiments.. Nature Methods 11:597–598.

Happy 2019 `\pi` Day—
Digits, internationally

Tue 12-03-2019

Celebrate `\pi` Day (March 14th) and set out on an exploration explore accents unknown (to you)!

This year is purely typographical, with something for everyone. Hundreds of digits and hundreds of languages.

A special kids' edition merges math with color and fat fonts.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
116 digits in 64 languages. (details)
Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
223 digits in 102 languages. (details)

Check out art from previous years: 2013 `\pi` Day and 2014 `\pi` Day, 2015 `\pi` Day, 2016 `\pi` Day, 2017 `\pi` Day and 2018 `\pi` Day.

Tree of Emotional Life

Sun 17-02-2019

One moment you're :) and the next you're :-.

Make sense of it all with my Tree of Emotional life—a hierarchical account of how we feel.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
A section of the Tree of Emotional Life.