The archive contains 1,708 quotes. From Dorothy Parker to Pinky and Brain, you're sure to find something special.
There are quote collections about love, heart, desire, life, death, god, mind, science.
Feeling lucky? Read 10 random quotes. Well, will you, punk?
All quotes about god
With my lost saints,—I love thee with the breath
Smiles, tears, of all my life!—and, if God choose,
I shall but love thee better after death.
But only God can make a tree.
Whose body Nature is, and God the soul.
But only God can make a tree.
The high untrespassed sanctity of space,
Put out my hand, and touched the face of God.
ar: God does not exist
If you believe in happiness it’s because of unhappiness.
If you believe in God, then you have to believe in the Devil.
He doesn’t give a damn.
I wish I were a moron.
My God! Perhaps I am!
all the books.
Disease, or sorrows strike him,
Inclines to think there is a God,
Or something very like Him.
So near is God to man,
When Duty whispers low, Thou must,
The youth replies, I can.
[God is dead: but considering the state the species Man is in, there will perhaps be caves, for ages yet, in which his shadow will be shown.]
To be no better than a homely swain;
To sit upon a hill, as I do now,
To carve out dials, quaintly, point by point,
Thereby to see the minutes how they run,
How many make the hour full complete;
How many hours bring about the day;
How many days will finish up the year;
How many years a mortal man may live.
What jealous pangs, what shy despairs I knew!
A love as deep as this, as true, as tender,
God grant another may yet offer you.
And seen strange lands from under the arched white sails of ships;
But the loveliest things of beauty God ever has showed to me,
Are her voice, and her hair, and eyes, and the dear red curve of her lips.
Whenever from my circling arms you stray;
This little world of mine has lost its light....
I hope to God, my dear, that you can say
The same to me.
my tongue caught in the roller of an electric typewriter?
shows through.
God one of man’s?
sky as well as the earth!
And nothing that moves but the cars...
God, if you wish for our love,
Fling us a handful of stars!
Convolutional neural networks
Nature uses only the longest threads to weave her patterns, so that each small piece of her fabric reveals the organization of the entire tapestry. â Richard Feynman
Following up on our Neural network primer column, this month we explore a different kind of network architecture: a convolutional network.
The convolutional network replaces the hidden layer of a fully connected network (FCN) with one or more filters (a kind of neuron that looks at the input within a narrow window).
Even through convolutional networks have far fewer neurons that an FCN, they can perform substantially better for certain kinds of problems, such as sequence motif detection.
Derry, A., Krzywinski, M & Altman, N. (2023) Points of significance: Convolutional neural networks. Nature Methods 20:.
Background reading
Derry, A., Krzywinski, M. & Altman, N. (2023) Points of significance: Neural network primer. Nature Methods 20:165â167.
Lever, J., Krzywinski, M. & Altman, N. (2016) Points of significance: Logistic regression. Nature Methods 13:541â542.
Neural network primer
Nature is often hidden, sometimes overcome, seldom extinguished. âFrancis Bacon
In the first of a series of columns about neural networks, we introduce them with an intuitive approach that draws from our discussion about logistic regression.
Simple neural networks are just a chain of linear regressions. And, although neural network models can get very complicated, their essence can be understood in terms of relatively basic principles.
We show how neural network components (neurons) can be arranged in the network and discuss the ideas of hidden layers. Using a simple data set we show how even a 3-neuron neural network can already model relatively complicated data patterns.
Derry, A., Krzywinski, M & Altman, N. (2023) Points of significance: Neural network primer. Nature Methods 20:165–167.
Background reading
Lever, J., Krzywinski, M. & Altman, N. (2016) Points of significance: Logistic regression. Nature Methods 13:541â542.
Cell Genomics cover
Our cover on the 11 January 2023 Cell Genomics issue depicts the process of determining the parent-of-origin using differential methylation of alleles at imprinted regions (iDMRs) is imagined as a circuit.
Designed in collaboration with with Carlos Urzua.
Akbari, V. et al. Parent-of-origin detection and chromosome-scale haplotyping using long-read DNA methylation sequencing and Strand-seq (2023) Cell Genomics 3(1).
Browse my gallery of cover designs.
Science Advances cover
My cover design on the 6 January 2023 Science Advances issue depicts DNA sequencing read translation in high-dimensional space. The image showss 672 bases of sequencing barcodes generated by three different single-cell RNA sequencing platforms were encoded as oriented triangles on the faces of three 7-dimensional cubes.
More details about the design.
Kijima, Y. et al. A universal sequencing read interpreter (2023) Science Advances 9.
Browse my gallery of cover designs.
Regression modeling of time-to-event data with censoring
If you sit on the sofa for your entire life, youâre running a higher risk of getting heart disease and cancer. âAlex Honnold, American rock climber
In a follow-up to our Survival analysis — time-to-event data and censoring article, we look at how regression can be used to account for additional risk factors in survival analysis.
We explore accelerated failure time regression (AFTR) and the Cox Proportional Hazards model (Cox PH).
Dey, T., Lipsitz, S.R., Cooper, Z., Trinh, Q., Krzywinski, M & Altman, N. (2022) Points of significance: Regression modeling of time-to-event data with censoring. Nature Methods 19:1513–1515.