Little fly, thy summer’s play
My careless hand hath brushed away.
Am not I a fly like thee,
Or art not thou a man like me.
For I dance, and drink, and sing
Till some blind hand doth brush my wing.
If that is life, and strength, and breath
And the word of thought is death
Then am I a happy fly?
If I live, or if I die.
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lunch break
Distractions and amusements, with a sandwich and coffee.
Here we are now at the middle of the fourth large part of this talk.
•
• get nowhere
• more quotes
EMBO Practical Course: Bioinformatics and Genome Analysis, 5–17 June 2017.
art + literature
daily quotation server archives
In the late 90’s I started (a good decade for starts) a daily quotation server project at www.quoteserver.ca. The domain is now defunct—some pages are partially viewable at the Way Back Machine.
Below is the list of quotes I had collected by the end of the life of the project. Most are about love—duh—and a few are jolly jests from funny trenches. You know, that place where mustard gas makes your eyes water.
The quotes weren’t scraped from quote archives—each is meaningful and hand-picked.
the quote archive
And now for full list of 1,600 other things worth reading. Such as everything Dorothy Parker has written and ... yes, even the Pinky and Brain quotes, which are a special kind of special.
Quote collections about love, heart, desire, life, death, god, mind, science.
Feeling lucky? Read 10 random quotes. Well, will you, punk?
Quotes about death
34
45
Sleep is a death, O make me try
By sleeping, what it is to die,
And as gently lay my head
On my grave, as now my bed.
By sleeping, what it is to die,
And as gently lay my head
On my grave, as now my bed.
Religio Medici, part II
48
I love thee with the love I seemed to lose
With my lost saints,—I love thee with the breath
Smiles, tears, of all my life!—and, if God choose,
I shall but love thee better after death.
With my lost saints,—I love thee with the breath
Smiles, tears, of all my life!—and, if God choose,
I shall but love thee better after death.
Sonnets from the Portuguese
132
To-morrow, and to-morrow, and to-morrow,
Creeps in this petty pace from day to day
To the last syllable of recorded time,
And all our yesterdays have lighted fools
The way to dusty death.
Out, out, brief candle!
Life’s but a walking shadow, a poor player
That struts and frets his hour upon the stage
And then is heard no more: it is a tale
Told by an idiot, full of sound and fury,
Signifying nothing.
Creeps in this petty pace from day to day
To the last syllable of recorded time,
And all our yesterdays have lighted fools
The way to dusty death.
Out, out, brief candle!
Life’s but a walking shadow, a poor player
That struts and frets his hour upon the stage
And then is heard no more: it is a tale
Told by an idiot, full of sound and fury,
Signifying nothing.
Macbeth, V. i. 19.
140
Half a league, half a league,
Half a league onward,
All in the valley of Death
Rode the six hundred.
Half a league onward,
All in the valley of Death
Rode the six hundred.
Charge of the Light Brigade
154
Sleep—Death without dying—living, but not life.
156
Death is sometimes a punishment, sometimes a gift;
To many it has come as a favor.
To many it has come as a favor.
157
The prince who kept the world in awe,
The judge whose dictate fix’d the law;
The rich, the poor, the great, the small,
Are levelled; death confounds ’em all.
The judge whose dictate fix’d the law;
The rich, the poor, the great, the small,
Are levelled; death confounds ’em all.
158
Because I could not stop for Death,
He kindly stopped for me,
The carriage held but just ourselves
And Immortality.
He kindly stopped for me,
The carriage held but just ourselves
And Immortality.
266
Life without a friend is like death without a witness.
299
Death comes with a crawl, or comes with a pounce,
And whether he’s slow or spry,
It isn’t the fact that you’re dead that counts,
But only, how did you die?
And whether he’s slow or spry,
It isn’t the fact that you’re dead that counts,
But only, how did you die?
How Did You Die?
337
Windows NT crashed.
I am the Blue Screen of Death.
No one hears your screams.
I am the Blue Screen of Death.
No one hears your screams.
340
Three things are certain:
Death, taxes and lost data.
Guess which has occurred.
Death, taxes and lost data.
Guess which has occurred.
417
Death is nature’s way of telling you to slow down.
431
Don’t be afraid of death so much as an inadequate life.
466
He is one of those people who would be enormously improved by death.
475
Those who fear death most are those who enjoy life least.
502
Marriage is the death of hope.
524
At six o’clock we cleaned our cells,
At seven all was still,
But the sough and swing of a mighty wing
The prison seemed to fill,
For the Lord of Death with icy breath
Had entered in to kill.
At seven all was still,
But the sough and swing of a mighty wing
The prison seemed to fill,
For the Lord of Death with icy breath
Had entered in to kill.
The Ballad of Reading Gaol
595
The smallest sprout shows there is really no death.
And if ever there was it led forward life, and does not
wait at the end to arrest it.
And if ever there was it led forward life, and does not
wait at the end to arrest it.
Song of Myself
645
I do not believe that any man fears to be dead, but
only the stroke of death.
only the stroke of death.
An Essay on Death
712
All tragedies are finish’d by a death,
All comedies are ended by a marriage.
All comedies are ended by a marriage.
Don Juan, c.iii, st. 9
729
Vivre est un maladie dont le sommeil nous soulage
toutes les 16 heures. C’est un pallatif. La mort
est le remede.
[Living is an illness to which sleep provides
relief every sixteen hours. It’s a palliative.
The remedy is death.]
toutes les 16 heures. C’est un pallatif. La mort
est le remede.
[Living is an illness to which sleep provides
relief every sixteen hours. It’s a palliative.
The remedy is death.]
Maximes et Pensees, ch. 2
812
Death hath so many doors to let out life.
The Custom of the Country, II.ii
885
Then, with no throbs of fiery pain,
No cold gradations of decay,
Death broke at once the vital chain,
And freed his soul the nearest way.
No cold gradations of decay,
Death broke at once the vital chain,
And freed his soul the nearest way.
Of Gray’s Odes
963
O death! I know it—’tis my famulus—
Thus turns to naught my fairest bliss!
That visions in abundance such as this
Must be disturbed by that dry prowler thus!
Thus turns to naught my fairest bliss!
That visions in abundance such as this
Must be disturbed by that dry prowler thus!
Faust
1092
For the crown of our life as it closes
Is darkness, the fruit there of dust;
No thorns go as deep as the rose’s,
And love is more cruel than lust.
Time turns the old days to derision,
Our loves into corpses or wives;
And marriage and death and division
Make barren our lives.
Is darkness, the fruit there of dust;
No thorns go as deep as the rose’s,
And love is more cruel than lust.
Time turns the old days to derision,
Our loves into corpses or wives;
And marriage and death and division
Make barren our lives.
Dolores
1130
Though they go mad they shall be sane.
Though they sink through the sea, they shall rise again.
Though lovers be lost, love shall not,
And death shall have no dominion.
Though they sink through the sea, they shall rise again.
Though lovers be lost, love shall not,
And death shall have no dominion.
1138
My life is light, waiting for the death wind,
Like a feather on the back of my hand.
Like a feather on the back of my hand.
1141
Death be not proud, though some have called thee
Mighty and dreadful, for, thou art not so,
For, those, whom thou think’st, thou dost overthrow,
Die not, poor death, nor yet canst thou kill me.
Mighty and dreadful, for, thou art not so,
For, those, whom thou think’st, thou dost overthrow,
Die not, poor death, nor yet canst thou kill me.
Holy Sonnets X
1142
Don’t strew me with roses after I’m dead.
When Death claims the light of my brow
No flowers of life will cheer me: instead
You may give me my roses now!
When Death claims the light of my brow
No flowers of life will cheer me: instead
You may give me my roses now!
1194
Suffer me to take your hand.
Suffer me to cherish you
Till the dawn is in the sky.
Whether I be false or true,
Death comes in a day or two.
Suffer me to cherish you
Till the dawn is in the sky.
Whether I be false or true,
Death comes in a day or two.
Mariposa
1311
Show me a love was done and through,
Tell me a kiss escaped its debt!
Son, to your death you’ll pay your due—
Women and elephants never forget.
Tell me a kiss escaped its debt!
Son, to your death you’ll pay your due—
Women and elephants never forget.
Ballade of Unfortunate Mammals
1319
Oh, it is sure as it is sad
That any lad is every lad,
And what’s a girl, to dare impore
Her dear be hers forevermore?
Though he be tried and he be bold,
And swearing death should he be cold,
He’ll run the path the others went....
But you, my sweet, are different.
That any lad is every lad,
And what’s a girl, to dare impore
Her dear be hers forevermore?
Though he be tried and he be bold,
And swearing death should he be cold,
He’ll run the path the others went....
But you, my sweet, are different.
Incurable
1446
In every parting there is an image of death.
1472
For the Angel of Death spread his wings on the blast,
And breathed in the face of the foe as he pass’d;
And the eyes of the sleepers wax’d deadly and chill,
And their hearts but once heaved, and for ever grew still!
And breathed in the face of the foe as he pass’d;
And the eyes of the sleepers wax’d deadly and chill,
And their hearts but once heaved, and for ever grew still!
The Destruction of Sennacherib
1476
To die, to sleep—
To sleep, perchance to dream, ay there’s the rub,
For in that sleep of death what dreams may come
When we have shuffled off this mortal coil,
Must give us pause; there’s the respect
That makes calamity of so long life.
To sleep, perchance to dream, ay there’s the rub,
For in that sleep of death what dreams may come
When we have shuffled off this mortal coil,
Must give us pause; there’s the respect
That makes calamity of so long life.
Hamlet
1485
The harder the conflict, the more glorious the triumph. What we obtain too cheap, we esteem too lightly; it is dearness only that gives everything its value. I love the man that can smile in trouble, that can gather strength from distress and grow brave by reflection. ’Tis the business of little minds to shrink; but he whose heart is firm, and whose conscience approves his conduct, will pursue his principles unto death.
1596
I do not want to believe that death is the gateway to another life. For me, it is a closed door. I do not say it is a step we must all take, but that it is a horrible and dirty adventure.
1672
Life is short. But death is very, very long.
Quicksand
news + thoughts
`k` index: a weightlighting and Crossfit performance measure
Similar to the `h` index in publishing, the `k` index is a measure of fitness performance.
To achieve a `k` index for a movement you must perform `k` unbroken reps at `k`% 1RM.
The expected value for the `k` index is probably somewhere in the range of `k = 26` to `k=35`, with higher values progressively more difficult to achieve.
In my `k` index introduction article I provide detailed explanation, rep scheme table and WOD example.
Dark Matter of the English Language—the unwords
I've applied the char-rnn recurrent neural network to generate new words, names of drugs and countries.
The effect is intriguing and facetious—yes, those are real words.
But these are not: necronology, abobionalism, gabdologist, and nonerify.
These places only exist in the mind: Conchar and Pobacia, Hzuuland, New Kain, Rabibus and Megee Islands, Sentip and Sitina, Sinistan and Urzenia.
And these are the imaginary afflictions of the imagination: ictophobia, myconomascophobia, and talmatomania.
And these, of the body: ophalosis, icabulosis, mediatopathy and bellotalgia.
Want to name your baby? Or someone else's baby? Try Ginavietta Xilly Anganelel or Ferandulde Hommanloco Kictortick.
When taking new therapeutics, never mix salivac and labromine. And don't forget that abadarone is best taken on an empty stomach.
And nothing increases the chance of getting that grant funded than proposing the study of a new –ome! We really need someone to looking into the femome and manome.
Dark Matter of the Genome—the nullomers
An exploration of things that are missing in the human genome. The nullomers.
Julia Herold, Stefan Kurtz and Robert Giegerich. Efficient computation of absent words in genomic sequences. BMC Bioinformatics (2008) 9:167
Clustering
Clustering finds patterns in data—whether they are there or not.We've already seen how data can be grouped into classes in our series on classifiers. In this column, we look at how data can be grouped by similarity in an unsupervised way.
▲ Nature Methods Points of Significance column: Clustering.
(read)
We look at two common clustering approaches: `k`-means and hierarchical clustering. All clustering methods share the same approach: they first calculate similarity and then use it to group objects into clusters. The details of the methods, and outputs, vary widely.
Altman, N. & Krzywinski, M. (2017) Points of Significance: Clustering. Nature Methods 14:545–546.
Background reading
Lever, J., Krzywinski, M. & Altman, N. (2016) Points of Significance: Logistic regression. Nature Methods 13:541-542.
Lever, J., Krzywinski, M. & Altman, N. (2016) Points of Significance: Classifier evaluation. Nature Methods 13:603-604.
What's wrong with pie charts?
In this redesign of a pie chart figure from a Nature Medicine article [1], I look at how to organize and present a large number of categories.
I first discuss some of the benefits of a pie chart—there are few and specific—and its shortcomings—there are few but fundamental.
I then walk through the redesign process by showing how the tumor categories can be shown more clearly if they are first aggregated into a small number groups.
(bottom left) Figure 2b from Zehir et al. Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients. (2017) Nature Medicine doi:10.1038/nm.4333