Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - contact me Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca on Twitter Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Lumondo Photography Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Pi Art Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Hilbertonians - Creatures on the Hilbert Curve
Twenty — minutes — maybe — more.Naomichoose four wordsmore quotes

words: beautiful


EMBO Practical Course: Bioinformatics and Genome Analysis, 5–17 June 2017.


art + literature

daily quotation server archives

In the late 90’s I started (a good decade for starts) a daily quotation server project at www.quoteserver.ca. The domain is now defunct—some pages are partially viewable at the Way Back Machine.

Below is the list of quotes I had collected by the end of the life of the project. Most are about love—duh—and a few are jolly jests from funny trenches. You know, that place where mustard gas makes your eyes water.

The quotes weren’t scraped from quote archives—each is meaningful and hand-picked.

the quote archive

And now for full list of 1,600 other things worth reading. Such as everything Dorothy Parker has written and ... yes, even the Pinky and Brain quotes, which are a special kind of special.

Quote collections about love, heart, desire, life, death, god, mind, science.

Feeling lucky? Read 10 random quotes. Well, will you, punk?

Quotes about heart

2
I have no wit, no words, no tears;
My heart within me like a stone
Is numb’d too much for hopes or fears;
Look right, look left, I dwell alone;
I lift mine eyes, but dimm’d with grief
No everlasting hills I see;
My life is in the falling leaf:
O Jesus, quicken me.
Christina Georgina Rossetti
A Better Ressurrection
5
For I am bound with fleshly bands,
Joy, beauty, lie beyond my scope;
I strain my heart, I stretch my hands,
And catch at hope.
Christina Georgina Rossetti
De Profundis
6
Rest, rest, for evermore
Upon a mossy shore;
Rest, rest at the heart’s core
Till time shall cease:
Sleep that no pain shall wake;
Night that no morn shall break
Till joy shall overtake
Her perfect peace.
Christina Georgina Rossetti
Dream Land
36
The mind has a thousand eyes,
And the heart but one;
Yet the light of a whole life dies,
When love is done.
Francis Bourdillon
Light
102
I give the all—I can no more,
Tho’poor the offering be;
My heart and lute are all the store
That I can bring to thee.
John Philip Kemble
Lodoiska, III. i.
105
And the song, from beginning to end,
I found again in the heart of a friend.
Henry Wadsworth Longfellow
The Arrow and the Song
114
Take thy beak from out my heart, and
take my form from off my door!
Quoth the Raven, "Nevermore."
Edgar Allan Poe
The Raven
121
My heart is like a singing bird
Whose nest is in a watered shoot;
My heart is like an apple-tree
Whose boughs are bend with thick-set fruit;
My heart is like a rainbow shell
That paddles in a halcyon sea;
My heart is gladder than all these
Because my love is come to me.
Christina Georgina Rossetti
A Birthday
148
For oft, when on my couch I lie
In vacant or in pensive mood,
They flash upon that inward eye
Which is the bliss of solitude;
And then my heart with pleasure fills,
And dances with the daffodils.
William Wordsworth
I Wandered Lonely as a Cloud
297
If I can stop one heart from breaking,
I shall not live in vain.
Emily Dickinson
300
What matter if I stand alone?
I wait with joy the coming years;
My heart shall reap where it has sown,
And garner up its fruit of tears.
John Burroughs
Waiting
301
And now, dear little children, who may this story read,
To idle, silly, flattering words, I pray you ne’er give heed;
Unto an evil counselor close heart, and ear, and eye,
And take a lesson from this tale of the Spider and the Fly.
Mary Howitt
The Spider and the Fly
313
The heart of man is made to reconcile contradiction.
David Hume
314
The head never rules the heart, but
just becomes the partner in crime.
Mignon McLaughlin
315
The heart is forever inexperienced.
Henry David Thoreau
316
When a young man complains that a young lady
has no heart, it is a pretty certain sign
that she has his.
George D. Prentice
415
Love is like an hourglass, with the heart filling up as the brain empties.
Jules Renard
545
Le coeur a ses raisons que la raison ne caonnait point.
[The heart has its reasons of which reason knows nothing.]
Blaise Pascal
Pensees
586
And the riverbank talks
Of the waters of March
It’s the end of the strain,
It’s the joy in your heart.
Antonio Carlos Jobim
Water of March
606
Greensleeves was all my joy,
Greensleeves was my delight,
Greensleeves was my heart of gold,
And who but Lady Greensleeves?
617
With women the heart argues, not the mind.
Matthew Arnold
Merope, 1.341
646
We should count time by heart-throbs.
Philip James Bailey
Festus
664
What the hand dare seize the fire?
And what shoulder, and what art,
Could twist the sinews of thy heart?
And when thy heart began to beat,
What dread hand? and what dread feet?
William Blake
The Tyger
669
Cruelty has a human heart,
And Jealousy a human face;
Terror the human form divine,
And Secrecy the human dress.
William Blake
Songs of Innocence and of Experience
695
Where my heart lies, my brain lies also.
Robert Browning
One Word More, xiv
718
So, we’ll go no more a roving
So late into the night,
Though the heart be still as loving,
And the moon be still as bright.
Lord Byron
So, We’ll Go No More a Roving
739
I cannot sing the old songs
I sang long years ago,
For heart and voice would fail me,
And foolish tears would flow.
C.A. Barnard
Fireside Thoughts
748
His heart runs away with his head.
George Colman the Younger
Who Wants a Guinea
782
I like a church; I like a cowl;
I love a prophet of the soul;
And on my heart monastic aisles
Fall like sweet strains, or pensive smiles;
Yet not for all his faith can see,
Would I that cowled churchman be.
Ralph Waldo Emerson
The Problem
794
To believe your own thought, to believe that what is
true for you in your private heart is true for all men—
that is genius.
Ralph Waldo Emerson
Essays, ii. Self-Reliance
828
Take heart, fair days will shine;
Take any heart, take mine!
W.S. Gilbert
881
I like work: it fascinates me. I can sit and look at it
for hours. I love to keep it by me: the idea of getting
rid of it nearly breaks my heart.
Jerome K. Jerome
Three Men in a Boat
904
There is an awful warmth about my heart
like a load of immortality.
John Keats
932
If all the earth were paper white
And all the sea were ink
Twere not enought for me to write
As my poor heart doth think.
John Lyly
Works
967
There are two tragedies in life.
One is to lose your heart’s desire.
The other is to gain it.
George Bernard Shaw
996
Take thy beak from out my heart,
and take thy form from off my door!
Quoth the Raven, "Nevermore."
Edgar Allan Poe
The Raven
997
A brain of feathers, and a heart of lead.
Alexander Pope
The Dunciad
1063
Words may be false and full of art,
Sighs are the natural language of the heart.
Thomas Shadwell
Psyche
1077
If thou didst ever hold me in thy heart,
Absent thee from felicity awhile,
And in this harsh world draw thy breath in pain,
To tell my story.
William Shakespeare
Hamlet, V.ii.360
1099
Here are fruits, flowers, leaves and branches,
And here is my heart which beats only for you.
Paul Verlaine
Romances sans Paroles
1106
I’ve lived to bury my desires,
And see my dreams corrode with rust;
Now all that’s left are fruitless fires
That burn my empty heart to dust.
Alexander Pushkin
1124
The holiest of all holidays are those
Kept by ourselves in silence and apart;
The secret anniversaries of the heart.
Henry Wadsworth Longfellow
1131
Time does not bring relief; you all have lied
Who told me time would ease me of my pain!
I miss him in the weeping of the rain;
I want him at the shrinking of the tide;
The old snows melt from every mountain-side,
And last year’s leaves are smoke in every lane;
But last year’s bitter loving must remain
Heaped on my heart, and my old thoughts abide.
There are a hundred places where I fear
To go, — so with his memory they brim.
And entering with relief some quiet place
Where never fell his boot or shone his face
I say, "There is no memory of him here!"
And so stand stricken, so remembering him.
Edna St. Vincent Millay
Time Does Not Bring Relief
1159
And Love! could thou and I with Fate conspire
To grasp this sorry Scheme of Things entire,
Would not we shatter it to bits—and then
Re-mould it nearer to the Heart’s Desire!
Omar Khayyam
Rubaiyat, LXXII, trans. by Edward Fitzgerald (1st ed.)
1175
love is a little white bird
and the flight of it so fast
you can’t see it
and you know it’s there
only by the faint whirr of its wings
and the hush song coming so low to your ears
you fear it might be silence
and you listen keen and you listen long
and you know it’s more than silence
for you get the hush song so lovely
it hurts and cuts into your heart
and what you want is to give more than you can get
and you’d like to write it but it can’t be written
and you’d like to sing it but you don’t dare try
because the little white bird sings it better than you can
Carl Sandburg
Little Word, Little White Bird
1181
I know I am but summer to your heart,
And not the full four seasons of the year;
And you must welcome from another part
Such noble moods as are not mine, my dear.
Edna St. Vincent Millay
Sonnets, xxvii
1182
This have I known always: Love is no more
Than the wide blossom which the wind assails,
Than the great tide that treads the shifting shore,
Strewing fresh wreckage gathered in the gales:
Pity me that the heart is slow to learn
What the swift mind beholds at every turn.
Edna St. Vincent Millay
Sonnets, xxix
1187
Deep is the pond-although the edge be shallow,
Frank is the sun, revealing fish and stone,
Climbing ashore to turtle-head and mallow—
Black at the center beats a heart unknown.
Desolate dreams pursue me out of sleep;
Weeping I wake; waking, I weep, I weep.
Edna St. Vincent Millay
Fatal Interview, xxxiii
1188
The heart once broken is a heart no more,
And is absolved from all a heart must be;
All that it signed or chartered heretofore
Is cancelled now, the bankrupt heart is free;
Edna St. Vincent Millay
Fatal Interview, l
1189
Heart in my breast,
This half a year now since you broke in two;
The world’s forgotten well, if the world knew.
Edna St. Vincent Millay
Fatal Interview, l
1191
My heart is warm with the friends I make,
And better friends I’ll not be knowing;
Yet there isn’t a train I wouldn’t take,
No matter where it’s going.
Edna St. Vincent Millay
Travel
1206
Man has places in his heart which do not yet exist,
and into them enters suffering in order that
they may have existence.
Leon Bloy
1212
I loved you once, nor can this heart be quiet,
For it would seem that love still lingers there,
But do not you be further troubled by it;
I would in no wise hurt you, oh my dear.
Alexander Pushkin
I Loved You Once
1219
I looked and saw your eyes
In the shadow of your hair
As a traveller sees the stream
In the shadow of the wood;
And I said, "My faint heart sights
Ah me! to longer there,
To drink deep and to dream
In that sweet solitude."
Dante Gabriel Rossetti
Three Shadows
1220
I looked and saw your heart
In the shadow of your eyes,
As a seeker sees the gold
In the shadow of the stream;
And I said, "Ah me! what art
Should win the immortal prize,
Whose want must make life cold
And Heaven a hollow dream?"
Dante Gabriel Rossetti
Three Shadows
1221
I looked and saw your love
In the shadow of your heart,
As a diver sees the perl
In the shadow of the sea;
And I murmured, not above
My breath, but all apart,—
"Ah! you can love, true girl,
And is your love for me?"
Dante Gabriel Rossetti
Three Shadows
1225
My true-love hath my heart, and I have his,
By just exchange one for another given:
I hold his dear, and mine he cannot miss,
There never was a better bargain driven:
My true-love hath my heart, and I have his.
Philip Sidney
A Ditty
1226
His heart in me keeps him and me in one,
My heart in him his thoughts and senses guides:
He loves my heart, for once it was his own,
I cherish his because in me it bides:
My true-love hath my heart, and I have his.
Philip Sidney
A Ditty
1228
Heart lives in the figure, so
What if gloom pervades the present?
All is fleeting, all will go;
What is gone will then be pleasant.
Alexander Pushkin
Should This Life Sometime Deceive You
1238
I must go on, till ends my rope,
Who from my birth was cursed with hope.
A heart in half is chaste, archaic;
But mine resembles a mosaic—
The thing’s become ridiculous!
Why am I so? Why am I thus?
Dorothy Parker
A Fairly Sad Tale
1239
New love, new love, shall I be forsaken?
One shall go a-wandering, and one of us must sigh.
Sweet it is to slumber, but how shall be awaken—
Whose will be the broken heart, when dawn comes by?
Dorothy Parker
The Last Question
1241
If wild my breast and sore my pride,
I bask in dreams of suicide;
If cool my heart and high my head,
I think, "How lucky are the dead!"
Dorothy Parker
Rhyme Against Living
1246
Who flings me silly talk of May
Shall meet a bitter soul;
For June was nearly spent away
Before my heart was whole.
Dorothy Parker
The False Friends
1259
Once, when I was young and true,
Someone left me sad—
Broke my brittle heart in two;
And that is very bad.
Love is for unlucky folk,
Love is but a curse.
Once there was a heart I broke;
And that, I think, is worse.
Dorothy Parker
A Very Short Song
1262
All of the blundering words I’ve spoken,
Little whilte love, forgive, forgive.
Once you went out, my heart fell, broken.
(Nevertheless, a girl must live.)
Dorothy Parker
Now at Liberty
1268
This is what I vow:
He shall have my heart to keep,
Sweetly will we stir and sleep...
thi sis what I pray:
Keep him by me tenderly;
Keep him sweet in pride of me...
This is what I know:
Lovers’ oaths are thin as rain;
Love’s a harbinger of pain...
Dorothy Parker
Somebody’s Song, extracts
1269
...Swift the measured sands may run;
Love like this is never done;
He and I are welded one:
This is what I vow.
...Keep me from the old distress;
Let me, for our happiness,
Be the one to love the less:
This is what I pray.
...Ever is my heart a-thirst,
Ever is my love accurst;
He is neither last nor first:
This is what I know.
Dorothy Parker
Somebody’s Song, extracts
1272
If I seek a lovelier part,
Where I travel goes my heart;
Where I stray my thought must go;
With me wanders my desire.
Best to sit and watch the snow,
Turn the lock, and poke the fire.
Dorothy Parker
Hearthside
1274
Because your eyes are slant and slow,
Because your hair is sweet to touch,
My heart is high again; but oh,
I doubt if this will get me much.
Dorothy Parker
Prophetic Soul
1276
If he whistles low and clear
When the insistent moon is near
And the secret stars are known—
Will your heart be still your own
Just because some words were true? ...
Lady, I was told them too!
Dorothy Parker
For an Unknown Lady
1278
Travel, trouble, music, art,
A kiss, a frock, a rhyme—
I never said they feed my heart,
But still they pass my time.
Dorothy Parker
Faute de Mieux
1280
When you rehearse your list of loves to me,
Oh, I can laugh and marvel, rapturous-eyed.
And you laugh back, nor can you ever see
the thousand little deaths my heart has died.
Dorothy Parker
A Certain Lady
1281
And you believe, so well I know my part,
That I am gay as morning, light as snow,
And all the straining things within my heart
You’ll never know.
Dorothy Parker
A Certain Lady
1290
Some men break your heart in two,
Some men fawn and flatter,
Some men never look at you;
And that cleans up the matter.
Dorothy Parker
Experience
1293
And each of us will sigh, and start
A-talking of a faded year,
And lay a hand above a heart,
And dry a pretty tear.
Dorothy Parker
The Dramatists
1295
Strange, that from lovely dreamings of the dead
I shall come back to you, who hurt me most.
You may not feel my hand upon your head,
I’ll be so new and inexpert a ghost.
Perhaps you will not know that I am near—
And that will break my ghostly heart, my dear.
Dorothy Parker
I Shall Come Back
1298
Dearest one, when I am dead
Never seek to follow me.
Never mount the quiet hill
Where the copper leaves are still,
As my heart is, on the tree
Standing at my narrow bed.
Dorothy Parker
Prayer for a Prayer
1302
She hated bleak and wintry things alone.
All that was warm and quick, she loved too well—
A light, a flame, a heart against her own;
It is forever bitter cold, in Hell.
Dorothy Parker
Tombstones in the Starlight: The Pretty Lady
1316
In May my heart was breaking—
Oh, wide the wound, and deep!
And bitter it beat at waking,
And sore it split in sleep.
And when it came November,
I sought my heart, and sighed,
"Poor thing, do you remember?"
"What heart was that?" it cried.
Dorothy Parker
Autumn Valentine
1317
Her mind lives tidily, apart
From cold and noise and pain,
And bolts the door against her heart,
Out wailing in the rain.
Dorothy Parker
Interior
1320
Let another cross his way—
She’s the one will do the weeping!
Little need I fear he’ll stray
Since I have his heart in keeping—
Let another hail him dear—
Little chance that he’ll forget me!
Only need I curse and fear
Her he loved before he met me.
Dorothy Parker
Mortal Enemy
1324
i carry your heart (i carry it in my heart)
e.e. cummings
92
1484
The moment you have in your heart this extraordinary thing called love and feel the depth, the delight, the ecstasy of it, you will discover that for you the world is transformed.
J. Krishnamurti
1485
The harder the conflict, the more glorious the triumph. What we obtain too cheap, we esteem too lightly; it is dearness only that gives everything its value. I love the man that can smile in trouble, that can gather strength from distress and grow brave by reflection. ’Tis the business of little minds to shrink; but he whose heart is firm, and whose conscience approves his conduct, will pursue his principles unto death.
Thomas Paine
1588
As you go down the
Stream of life in your
Little canoe, I hope
You will have a jolley
Time, with plenty of
Room for two,
Love is to the human
Heart as sunshine is
To flowers, And friendship
Is the fairest thing in
This cold world of ours.
Thomas Rigdon Foote
Autograph Albums and Bible of Ella Beaver Calhoun
1590
The heart has reasons that reason does not understand.
Jacques Benigne Bossuel
1634
Something made of nothing, tasting very sweet,
A most delicious compound, with ingredients complete;
But if, as on occasion, the heart and mind are sour,
It has no great significance, and loses half its power.
Mary. E. Buell
The Kiss
1638
A man had given all other bliss,
And all his worldly worth for this,
To waste his whole heart in one kiss
Upon her perfect lips.
Lord Tennyson
Sir Launcelot and Queen Guinevere
1639
Though I know he loves me,
Tonight my heart is sad;
His kiss was not so wonderful
As all the dreams I had.
Sara Teasdale
The Kiss
1671
Be patient toward all that is unsolved in your heart and to try to love the questions themselves like locked rooms and like books that are written in a very foreign tongue. Do not now seek the answers, which cannot be given you because you would not be able to live them. And the point is, to live everything. Live the questions now. Perhaps you will then gradually, without noticing it, live along some distant day into the answer.
Rainer Maria Rilke
Letters on Love (Rilke on Love and Other Difficulties)
VIEW ALL

news + thoughts

Tabular Data

Tue 11-04-2017
Tabulating the number of objects in categories of interest dates back to the earliest records of commerce and population censuses.

After 30 columns, this is our first one without a single figure. Sometimes a table is all you need.

In this column, we discuss nominal categorical data, in which data points are assigned to categories in which there is no implied order. We introduce one-way and two-way tables and the `\chi^2` and Fisher's exact tests.

Altman, N. & Krzywinski, M. (2017) Points of Significance: Tabular data. Nature Methods 14:329–330.

...more about the Points of Significance column

Happy 2017 `\pi` Day—Star Charts, Creatures Once Living and a Poem

Tue 14-03-2017


on a brim of echo,

capsized chamber
drawn into our constellation, and cooling.
—Paolo Marcazzan

Celebrate `\pi` Day (March 14th) with star chart of the digits. The charts draw 40,000 stars generated from the first 12 million digits.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
12,000,000 digits of `\pi` interpreted as a star catalogue. (details)

The 80 constellations are extinct animals and plants. Here you'll find old friends and new stories. Read about how Desmodus is always trying to escape or how Megalodon terrorizes the poor Tecopa! Most constellations have a story.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Find friends and stories among the 80 constellations of extinct animals and plants. Oh look, a Dodo guardings his eggs! (details)

This year I collaborate with Paolo Marcazzan, a Canadian poet, who contributes a poem, Of Black Body, about space and things we might find and lose there.

Check out art from previous years: 2013 `\pi` Day and 2014 `\pi` Day, 2015 `\pi` Day and and 2016 `\pi` Day.

Data in New Dimensions: convergence of art, genomics and bioinformatics

Tue 07-03-2017

Art is science in love.
— E.F. Weisslitz

A behind-the-scenes look at the making of our stereoscopic images which were at display at the AGBT 2017 Conference in February. The art is a creative collaboration with Becton Dickinson and The Linus Group.

Its creation began with the concept of differences and my writeup of the creative and design process focuses on storytelling and how concept of differences is incorporated into the art.

Oh, and this might be a good time to pick up some red-blue 3D glasses.

BD Genomics 3D art exhibit - AGBT 2017 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
A stereoscopic image and its interpretive panel of single-cell transcriptomes of blood cells: diseased versus healthy control.

Interpreting P values

Thu 02-03-2017
A P value measures a sample’s compatibility with a hypothesis, not the truth of the hypothesis.

This month we continue our discussion about `P` values and focus on the fact that `P` value is a probability statement about the observed sample in the context of a hypothesis, not about the hypothesis being tested.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Interpreting P values. (read)

Given that we are always interested in making inferences about hypotheses, we discuss how `P` values can be used to do this by way of the Benjamin-Berger bound, `\bar{B}` on the Bayes factor, `B`.

Heuristics such as these are valuable in helping to interpret `P` values, though we stress that `P` values vary from sample to sample and hence many sources of evidence need to be examined before drawing scientific conclusions.

Altman, N. & Krzywinski, M. (2017) Points of Significance: Interpreting P values. Nature Methods 14:213–214.

Background reading

Krzywinski, M. & Altman, N. (2017) Points of significance: P values and the search for significance. Nature Methods 14:3–4.

Krzywinski, M. & Altman, N. (2013) Points of significance: Significance, P values and t–tests. Nature Methods 10:1041–1042.

...more about the Points of Significance column

Snellen Charts—Typography to Really Look at

Sat 18-02-2017

Another collection of typographical posters. These ones really ask you to look.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Snellen charts designed using physical constants, Braille and elemental abundances in the universe and human body.

The charts show a variety of interesting symbols and operators found in science and math. The design is in the style of a Snellen chart and typset with the Rockwell font.