events + announcements

▲ NASA to send our ‘cosmic hello’ with human genomes to the Moon | Benoit Faiveley, founder of the Sanctuary project gives the Sanctuary disc a visual check at CEA LeQ Grenoble (image: Vincent Thomas) (...more)

▲ NASA to send our ‘cosmic hello’ with human genomes to the Moon | Sanctuary team examines the Life disc at INRIA Paris Saclay. (image: Benedict Redgrove) (...more)

▲ 2024 π DAY | Digit Garden: Sunflowers ho! (...more)

▲ A Map of Nothing | Huge empty areas of the universe called voids could help solve the greatest mysteries in the cosmos. (data visualization: Martin Krzywinski, art direction: Jen Christianen / article: Michael Lemonick / Scientific American, January 2024) (...more)

▲ 2023 π DAY | Repeated Sequence: A Modular Synthesizer Experience (vocals: Esther (age 6), Anja Øyen Vister, Nüket Bilgen, sound design: Gregory Coles & Martin Krzywinski) (...more)

▲ Circuits of inheritance | The process of determining the parent-of-origin using differential methylation of alleles at imprinted regions (iDMRs) is imagined as a circuit. (cover design Carlos Urzua & Martin Krzywinski, Akbari, V. et al. (2023) Cell Genomics 3(1)) (...more)

▲ INTERSTELLAR: a Rosetta Stone for DNA sequencing | 672 barcode bases from three sequencing platforms encoded on the faces of 7-dimensional cubes. (cover design Martin Krzywinski, Kijima, Y. et al. A universal sequencing read interpreter (2023) Science Advances 9) (...more)

▲ Music video for Max Cooper's Ascent | Read about my 5-dimensional animation for Max Cooper's “Ascent” from the album “Unspoken Words”. (music Max Cooper, animation Martin Krzywinski) (...more)

▲ MIT Museum Gene Cultures Exhibit | Read about my artwork at the newly reopened MIT Museum. (visualization Martin Krzywinski, art direction Jacob Montz) (...more)

▲ Targets of precision medicine | Design shows genomic mutations and cancer treatment options for 570 cases. (cover design Martin Krzywinski & Emma Titmuss, Pleasance E et al. Ann. Oncol 33:939–949) (...more)

▲ 3,117,275,501 Bases, 0 Gaps | See How Scientists Put Together the Complete Human Genome (text: Clara Moskowitz, art direction: Jen Christiansen, graphic: Martin Krzywinski, source: UCSC Genome Browser) (...more)

▲ Anatomy of the SARS-CoV-2 virus | Structure of genes and ORFs in the variants of the virus, with a focus on differences due to mutation. (...more)

▲ A bloom of 200 million sequences | Highly efficient distributed computing method for the reconstruction of evolutionary trees from very large datasets. (cover design Martin Krzywinski, Deep distributed computing to reconstruct extremely large lineage trees, Konno et al.) (...more)

▲ A kaleidoscope of heterogeneity in GBM | Heterogeneity as a kaleidoscope generated from immunofluorescence staining of the glial and neuronal markers in GBM (cover design Martin Krzywinski, LeBlanc VG et al. Cancer Cell 40:379–392) (...more)

▲ 2022 π DAY | three one four: a number of digits — hear what you've been missing (music: Gregory Coles, words & art: Emma Beauxis-Aussalet / concept & engraving: Martin Krzywinski) (...more)

▲ Gene Genie | Evolutionary properties of sequences at the extremes of the evolvability spectrum. (cover design Martin Krzywinski, The evolution, evolvability and engineering of gene regulatory DNA, Vaishnav et al.) (...more)

▲ PNAS Cover | Earth BioGenome Project — a moonshot at Earth (Martin Krzywinski (design), Lewin HA et al., The Earth BioGenome Project 2020: Starting the clock. (2022) PNAS 119(4) e2115635118) (...more)

▲ The variants of SARS-Cov-2 | Of interest and of concern: The genomes of all 13 WHO variants represented as paths. (...more)

▲ The variants of SARS-Cov-2 | Of interest and of concern: The genomes of all 13 WHO variants represented as paths. (...more)

▲ The human genome: a research ultramarathon | The genome as a spiral, annotated with genes associated with Mendelian disorders and mutation clusters from a pan-cancer analysis of advanced tumors. (Martin Krzywinski (design), Laura M. Zahn (article), OMIM; Pleasance et al, Nat Cancer (2020)) (...more)

▲ Down Here / Moon Above | From Flunk's History of Everything Ever album — a song for the Moon (Flunk (music), Martin Krzywinski (design)) (...more)

▲ Transcendence | A tactile audio-visual installation in collaboration with Max Cooper, Salvador Breed and AND&. (Martin Krzywinski (animation), Max Cooper & Salvador Breed (music)) (...more)

▲ 2021 π DAY | A forest of digits — bat cave and underwater remix. (Martin Krzywinski) (...more)

▲ 2021 π DAY | A forest of digits. (Martin Krzywinski) (...more)

▲ Graphical abstract design guidelines | Practical tips and redesign examples for creating scientific graphical abstracts. (Cell (2010) 140:148–160) (...more)

▲ Graphical abstract design guidelines | Practical tips and redesign examples for creating scientific graphical abstracts. (Cell (2010) 140:49–61) (...more)

▲ She said, he said. | Analysis of word usage in 2020 U.S. Presidential and Vice-Presidential Debates. (...more)

▲ Nature Methods Points of Significance | Celebrating 50 columns of clear explanations of statistics. (Naomi Altman & Martin Krzywinski, with Bjørnstad, Blainey, Bzdok, Das, Greco, Grewal, Kulesa, Lever, Luta, Puga, Shea, Smucker) (...more)

▲ Gene Machines | An assembly of shifting soundscapes, textures and rhythmic loops produced by laboratory machines. (music: Segue, label: ADSR Collective) (...more)

▲ Gene Machines | An assembly of shifting soundscapes, textures and rhythmic loops produced by laboratory machines. (music: Segue, label: ADSR Collective) (...more)

▲ Gene Machines | An assembly of shifting soundscapes, textures and rhythmic loops produced by laboratory machines. (music: Segue, label: ADSR Collective) (...more)

▲ Gene Machines | An assembly of shifting soundscapes, textures and rhythmic loops produced by laboratory machines. (music: Segue, label: ADSR Collective) (...more)

▲ Gene Machines | An assembly of shifting soundscapes, textures and rhythmic loops produced by laboratory machines. (music: Segue, label: ADSR Collective) (...more)

▲ Gene Machines | An assembly of shifting soundscapes, textures and rhythmic loops produced by laboratory machines. (music: Segue, label: ADSR Collective) (...more)

▲ Virus Mutations Reveal How COVID-19 Really Spread | Genetic sequences of the coronavirus tell story of when the virus arrived in each country and where it came from. (text: Mark Fischetti, art direction: Jen Christiansen, graphic: Martin Krzywinski, source: Nextstrain (enabled by data from GISAID)) (...more)

▲ Our cover of Nature Cancer April 2020 issue shows mutation spectra of 570 advanced tumor genomes. | The cover accompanies our report 'Pan-cancer analysis of advanced patient tumors reveals interactions between therapy and genomic landscapes.' (design: Emma Titmuss & Martin Krzywinski, data: Pleasance et al. Nat Cancer 1:452–468.) (...more)

▲ Colorful SARS-CoV-2 genome desktops for your foul mood. | A ball of 56 cornavirus genomes. (Martin Krzywinski) (...more)

▲ Do your part and flatten the curve. A motivational poster. | Infected fraction for R0 = 3 (red) to R0 = 1.5 (purple) from a S-I-R model. (Martin Krzywinski) (...more)

▲ Genomes of isolates of SARS-CoV-2, the novel coronavirus that causes COVID-19. | Run away. Or better, stay home and explore the poster. (concept / martin krzywinski, cydney nielsen, ian bosdet, design / martin krzywinski) (...more)

▲ Genomes of isolates of SARS-CoV-2, the novel coronavirus that causes COVID-19. Arranged in a ball. | Run away. Or better, stay home and explore the poster (concept / martin krzywinski, cydney nielsen, ian bosdet, design / martin krzywinski) (...more)

▲ Genomes of Deadly Viruses and Bacteria | Run away. Or better, stay home and explore the poster. Updated with SARS-CoV-2. (concept / martin krzywinski, cydney nielsen, ian bosdet, design / martin krzywinski, jonathan corum) (...more)

▲ 2020 π DAY | Digits, poetically. Meet the piku (π-ku, パイク). (Martin Krzywinski) (...more)

▲ Aleph 2. Counting the rationals. | Yearning for the Infinite, Alex Cooper at Barbican Hall, London. (video Martin Krzywinski, photo Michal Augustini) (...more)

▲ Aleph 2. Power set of reals. | Yearning for the Infinite, Alex Cooper at Barbican Hall, London. (video Martin Krzywinski, photo Alex Kozobolis) (...more)

▲ 1-bit 3.6 gigapixel Moon map | 6,733 locations on the moon. View centered on Taurus-Littrow Valley Apollo 17 site. (Martin Krzywinski, LROC) (...more)

▲ 1-bit 0.1 and 10 gigapixel Solar System map | 800,000 objects in the Solar System and counting. View centered on Earth. (Martin Krzywinski, Ephemeris by Miriade) (...more)

▲ 1-bit 0.1 and 10 gigapixel sky charts | Millions of stars and thousands of everything else. View centered on the Andromeda Galaxy (M31). (Martin Krzywinski, via SIMBAD) (...more)

▲ DNA on 10th — it's like night and day. | Science this way! Wayfinding signs on Vancouver's Health Care Corridor (10th Avenue, at Oak Street). (Martin Krzywinski, PUBLIC architecture + communication) (...more)

▲ DNA on 10th. | Science this way! Wayfinding signs on Vancouver's Health Care Corridor (10th Avenue, at Oak Street). (Martin Krzywinski, PUBLIC architecture + communication) (...more)

▲ 2019 π DAY | Hundreds of digits and hundreds of languages. Oh, and a kids' edition! (Martin Krzywinski) (...more)

▲ Brain & Mind Symposium | Brains drawing brains in Helsinki. (...more)

▲ Powered by research | Ride to Conquer Cancer jersey shows a visualization of cancers treated at BC Cancer. (data visualization by Martin Krzywinski) (...more)

▲ Large-scale structure of the Universe | Superclusters and Voids. (M Krzywinski) (...more)

▲ Sanctuary | Eternity for humanity. (gigapixel production sample, 5 cm diameter, launching to the Moon in 2019) (...more)

▲ Papillary thyroid carcinoma cover design. | Molecular Case Studies, April 2018. (design by Martin Krzywinski, based on Ronsley at al. in the issue) (...more)

▲ 2018 π DAY | Boonies, burbs and boutiques of π. Let's go places. (Martin Krzywinski, Jake Lever) (...more)

▲ 2018 π DAY | Let's go places. (Martin Krzywinski, Jake Lever) (...more)

▲ 2018 π DAY | On the (many) road(s). (Martin Krzywinski, Jake Lever) (...more)

▲ Human Versus Machine: the making of the Nature 10 cover. | Balancing subjective design with objective optimization. (Martin Krzywinski) (...more)

▲ In silico flurries | Explore the symmetry and beauty in these simulated snowflakes. (Martin Krzywinski, snowflake model by Gravner-Griffeath) (...more)

▲ Genes that make us sick — where disease hides in the genome. | Illustration in 'The Objects that Power the Global Economy' showing location of genes in the human genome implicated in disease. (Martin Krzywinski, in collaboration with Quartz) (...more)

▲ Personal Oncogenomics Program 5 Year Anniversary. | The POG art shows 545 cases studied over the course of 5 years and is freely available. (art by Martin Krzywinski, Genome Sciences Center, BC Cancer Agency, BC Cancer Foundation) (...more)

▲ HAPPY 2017 π DAY | Celebrate with sky charts based on the digits of π and constellations of extinct animals and plants (Martin Krzywinski) (...more)

▲ Data in New Dimensions: convergence of art, genomics and bioinformatics. | Stereoscopic art exhibit at AGBT 2017. (Martin Krzywinski, in collaboration with Becton Dickinson and The Linus Group ) (...more)

▲ The Ptolemaic Clock. | Confuse and delight with this clock: bezels move and hands are fixed. (Martin Krzywinski) (...more)

▲ Eyes on the Universe. | Technically accurate Snellen Eye charts with different alphabets. (Martin Krzywinski) (...more)

▲ Essentials of Data Visualization—Thinking about drawing data and communicating science. | 8-part video series. (Martin Krzywinski, Kim Bell-Anderson & Philip Poronnik, collaboration with University of Sydney) (...more)

▲ 22 July 2016 — happy π approximation day. | This year's posters show π-approximate packing of warped circles that embody the approximation. (art and concept by Martin Krzywinski) (...more)

▲ Visualizing clonal evolution in cancer. | Guidelines for presenting clone evolution plots to visualize temporal, phylogenetic, and spatial aspects of a tumor. (Krzywinski, M (2016) Molecular Cell 62:652-656.) (...more)

▲ 14 March 2016 — HAPPY π DAY | This year's π day art comes with gravity in celebration of LIGO's detection of gravity waves in February. (art and concept by Martin Krzywinski) (...more)

▲ Petabase party—nucleotides and cupcakes | Celebration to mark 1,014,546,735,270,357 bases sequenced. (photos by Martin Krzywinski) (...more)

▲ Bacterial diversity in household dust. | The latest of my three Scientific American Graphic Science visualizations. (design Martin Krzywinski, Jeannie Hunnicutt, art direction Jen Christiansen) (...more)

▲ Hitchmas 2015. Be here. | Library Bar, Copenhagen. (...more)

▲ Science not communicated is science not done. | Let that be a warning to you. (...more)

▲ Corn World: Teeth on the Cob | Jurassic World triceratops assembly is actually corn. (poster by M Krzywinski) (...more)

▲ Gene Volume Control | Tissue-specific epigenetic modification in genome regions associated with disease (Scientific American 312(6) Graphic Science, M Krzywinski) (...more)

▲ 14 March 2015 — HAPPY π DAY | Exactly on 3.14.15 at 9:26:53. (3,628 digits of π, M Krzywinski) (...more)

▲ If one of the Spocks is missing, you have color blindness. | Live long and prosper. (image from imagebuddy.com) (...more)

▲ Nature Methods Points of Significance | Now free acceess. Part of statistics for biologists resource. (Krzywinski, Altman, Blainey) (...more)

▲ miRNA in diffuse large B-cell lymphoma | A cancer miRNome. (Lim et al. Genome Biology (2015) 16:18, image by M Krzywinski) (...more)

▲ Viewing the Genome on a Blackberry | Doctors access patient data from their pocket. (Patrick Soon-Shiong in photo, photo from Forbes.com) (...more)

▲ High-throughput next generation sequencing applied to infectious diseases | EMBO global exchange lecture course (Tunis, September 15–25, Circos lectures on September 22) (...more)

▲ Scientific American Genome Infographic | Denisovan, Chimp, Bonobo, and Gorilla — it's a monkey's blueprint (M Krzywinski) (...more)

▲ Hilbert Curve Art Posters | Circles begone! (M Krzywinski) (...more)

▲ Creatures from the Hilbert Curve | 14 Classes and 13,689 personalities. (M Krzywinski) (...more)

▲ 22 July 2014 — Happy π Approximation Day | Accuracy of the first 10,000 m/n approximations of π. (M Krzywinski) (...more)

▲ Circos at Smithsonian's Genome Zone | Circos diagram representing genome data from TCGA. (M Krzywinski, Photo by Emilia Lim) (...more)

▲ HAPPY 2014 π DAY | Frequency distribution of π digits up to Feynman Point in groups of 6. (M Krzywinski) (...more)

▲ HAPPY 2014 π DAY | π digits up to Feynman Point on a path, folded with HP lattice model. (M Krzywinski, algorithm: replica exchange Monte Carlo) (...more)

▲ Practise visual aesthetics | Draw reasonably. (M Krzywinski) (...more)

▲ Beautiful Science at the British Library | Circos information graphic Circles of Life part of exhibit. 20 Feb — 26 May 2014 (M Krzywinski) (...more)

▲ 20 imperatives of science | The limitations of evidence. (Sutherland WJ, Spiegelhalter D & Burgman M, Policy: Twenty tips for interpreting scientific claims (2013) Nature 503:335–337.) (...more)

▲ Cover of Fall 2013 UCSF Magazine. | Precision medicine issue. (illustration by M Krzywinski) (...more)

▲ Presenting at Wired Data|Life 2013 Conference in NYC. | November 5-6 @ New York City, #wiredhealth (...more)

▲ Circos reaches 500 citations in scientific literature. | (A sample of published Circos images) (...more)

▲ Sacred Lotus genome Circos image on Genome Informatics 2013 Program Cover | Oct 30-Nov2 2013, CSHL (Lotus and Hummingbird by Robert Hooper, Sacred lotus genome, Ming et al. 2012 Genome Biology) (...more)

▲ Nature Methods Points of View Collection. | All 35 columns are currently open access at Nature Methods. (Wong ∙ Krzywinski ∙ Gehlenborg ∙ Nielsen ∙ Soresh ∙ Kjaegaard ∙ Savig ∙ Cairo) (...more)

▲ Free the data. | Stories of cancer survivors embedded in a mural of genome science and street art. (design/concept Joanna Rudnick/Martin Krzywinski, art Aaron De La Cruz) (...more)

▲ Proteins on drugs (remix). | We discuss this image, which appeared on the cover of Nature Biotech (Sept 2012), in our Points of View column. (design/implementation Erica Savig, Bodenmiller et al. Nat Biotech 30, 858 (2012)) (...more)

▲ Birds among wolves. | From my lost and abandoned art incubator. (Martin Krzywinski) (...more)

▲ Circos, putting the round on cancer. | "According to Dr. Timothy Ley, traditional methods for categorizing acute myeloid leukemia were imprecise." (Cancers Share Gene Patterns, Studies Affirm, NYT, 1 May 2013, Peter Newcomb for The New York Times) (...more)

▲ Keynote at VIZBI 2013 | Visual Design Principles (21 March 2013, Broad Institute (Boston, MA), fractal tree of life by onezoom.org) (...more)

▲ HAPPY 2013 π DAY | Celebrate 3.14 on March 14th (Martin Krzywinski) (...more)

▲ Type Peep Show | The private curves of letters. (Martin Krzywinski) (...more)

▲ Circos motif signals big data ahead! | Nature cover and Explorer app make things pretty with round. (Nature cover by Carl DeTorres, 6 September 2012) (...more)

▲ Presenting at the Bloomberg Businessweek 2013 Design Conference | Science loves design, but doesn't always know it. (Martin Krzywinski & Alberto Cairo, 14 January 2013, San Francisco) (...more)

▲ Trends in Genetics October 2012 Special Issue | Nature and human life are as various as our several constitutions. Who shall say what prospect life offers to another? — Henry David Thoreau (Martin Krzywinski) (...more)

▲ Circos Cancer Genome Display | Dr. John Carpten, left, and Dr. David Craig with a cancer genome display. New strategies attack cancer at the genetic level. (Joshua Lott / NYT) (...more)

▲ Bang. That's the genomes, exploding. | Scientific terminology. Longer, harder and more arcane. (James Gorman / NYT, Image by Martin Krzywinski) (...more)

▲ Biology gets physical. Astrophysical. | What is it? A cross section of a mouse vein. (PNAS May 1 2012; 109 (18)) (...more)

▲ Transition probabilities of digits of e, φ and π | Numbers turned into abstract art. Transition probabilities becomes bubbles for each i → j transition. (Martin Krzywinski, created with Circos / circos.ca) (...more)

▲ Digits of e, φ and π | Numbers turned into abstract art. Progression and transition probabilities are shown as links and bubble plots. (concept / Cristian Ilies Vasile, created with Circos / circos.ca) (...more)

▲ Digits of π | Digits of π wrapped around a spiral. (generated with Circos (circos.ca), Martin Krzywinski) (...more)

▲ Circos Fruit Salad | Circos demonstrates sequence synteny between genomes of peach, apple and strawberry. ( Whole genome comparisons of Fragaria, Prunus and Malus... / Jung et al., 2012 BMC Genomics 13:129.) (...more)

▲ The hive plots are coming | The node link diagram shows the structure of the Flare visualization kit (d3.js + hive plots / mike bostock, post processing / martin krzywinski) (...more)

▲ ASCII art using multiple proportionally spaced type faces | The pioneer 10 plaque is rendered here with human chromosome 1 sequence. (ascii art / martin krzywinski) (...more)

▲ Gondor, looking north. | Well, almost. A stunning panorama of Laugavegur, approaching Landmannalaugar. Iceland: it’s all about pretty. (photography / martin krzywinski) (...more)

▲ Literature 2.0 | Distilling spam into poems in the style of ee cummings (poetry from spam / ee spammings / martin krzywinski) (...more)

▲ Near Jökulsárlón, on the way to Höfn | Looking east across the Norwegian sea. Iceland: it’s all about pretty. (photography / martin krzywinski) (...more)

▲ Hive plots | A method to rationally visualize networks (concept + analysis + layout / martin krzywinski) (...more)

▲ Circos | Your compass in a forest of data. (concept + design / martin krzywinski) (...more)

▲ Thematic profiles of 2008 US presidential debates | Obama and McCain explore themes: nuclear, fear, military, foreign places, economy, health, environment (analysis + visualization / martin krzywinski) (...more)

▲ Hive panel - a collection of hive plots | Examining relationships between connectivity, betweenness and pagerank in the protein interaction network (concept + analysis + layout / martin krzywinski) (...more)

▲ Genome Sciences Center High-Throughput Sequencing Laboratory | We sequence a human genome every 17 minutes, or less (photography / martin krzywinski) (...more)

▲ Circos | Some light in the darkness of data warehouses. (concept + design / martin krzywinski) (...more)

▲ SFU AQ Magazine / 2011 APR | adapted from Jones SJ, Laskin J, Li YY et al. 2010 Evolution of an adenocarcinoma in response to selection by targeted kinase inhibitors Genome Biol 11:R82 (photography + design / martin krzywinski) (...more)

▲ Circos | Visualize tables. Bury the spreadsheet. (concept + design / martin krzywinski) (...more)

▲ Genome Sciences center GENESIS compute cluster | 5,040 cores / 20TB RAM / 700TB SSD STORAGE / Infiniband 40Gbs (photography / martin krzywinski) (...more)

▲ Submissions for the EMBO 2011 cover contest | (photography / martin krzywinski) (...more)

▲ Circos in print | Wired, New York Times, Conde Nast Portfolio, American Scientist, iGenetics, Science, Nature, PLoS, Genome Research, Plant Cell, Genome Biology, EMBO JOURNAL (...more)