Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - contact me Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca on Twitter Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Lumondo Photography Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Pi Art Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Hilbertonians - Creatures on the Hilbert Curve
Love itself became the object of her love.Jonathan Safran Foercount sadnessesmore quotes


In Silico Flurries: Computing a world of snow. Scientific American. 23 December 2017


art + design

Math geek? If you like the clean geometric design of the type posters, you may enjoy something even more mathematical. Design that transcends repetition: Art of Pi, Phi and e posters.

Visions of Type

eye on the universe

Designed in the style of a Snellen eye chart, these posters insist that you look. Font is Rockwell.


Typographical posters of how the world works in the style of Snellen eye charts
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Snellen Chart of abundance of the elements in the universe. (BUY ARTWORK)

Typographical posters of how the world works in the style of Snellen eye charts
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Snellen Chart of physical constants. (BUY ARTWORK)

Typographical posters of how the world works in the style of Snellen eye charts
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Snellen Chart typeset in Braille. (BUY ARTWORK)

chirping in proxima nova

A new line of typographical posters featuring Proxima Nova. The posters present the bird song mnemonics against the plumage color of the bird.


Typographical posters of bird song
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Potato chip! — song of the American Goldfinch (Spinus tristis). (BUY ARTWORK)

Typographical posters of bird song
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Who cooks for you? — song of the Barred Owl (Strix varia). (BUY ARTWORK)

Typographical posters of bird song
 / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Clear. Wick, wick, wick. — song of the Northern Flicker (Colaptes auratus). (BUY ARTWORK)

letter forms, sensually revealed and stacked

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Type peep show — the private curves of letters. (BUY ARTWORK)
Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Sixteen ands — a consensus of conjunctions. (BUY ARTWORK)
Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
Sixteen faces — fonts in argument. (BUY ARTWORK)
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news + thoughts

Find and snap to colors in an image

Sat 29-12-2018

One of my color tools, the colorsnap application snaps colors in an image to a set of reference colors and reports their proportion.

Below is Times Square rendered using the colors of the MTA subway lines.


Colors used by the New York MTA subway lines.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Times Square in New York City.
Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Times Square in New York City rendered using colors of the MTA subway lines.
Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Granger rainbow snapped to subway lines colors from four cities. (zoom)

Take your medicine ... now

Wed 19-12-2018

Drugs could be more effective if taken when the genetic proteins they target are most active.

Design tip: rediscover CMYK primaries.

More of my American Scientific Graphic Science designs

Ruben et al. A database of tissue-specific rhythmically expressed human genes has potential applications in circadian medicine Science Translational Medicine 10 Issue 458, eaat8806.

Predicting with confidence and tolerance

Wed 07-11-2018
I abhor averages. I like the individual case. —J.D. Brandeis.

We focus on the important distinction between confidence intervals, typically used to express uncertainty of a sampling statistic such as the mean and, prediction and tolerance intervals, used to make statements about the next value to be drawn from the population.

Confidence intervals provide coverage of a single point—the population mean—with the assurance that the probability of non-coverage is some acceptable value (e.g. 0.05). On the other hand, prediction and tolerance intervals both give information about typical values from the population and the percentage of the population expected to be in the interval. For example, a tolerance interval can be configured to tell us what fraction of sampled values (e.g. 95%) will fall into an interval some fraction of the time (e.g. 95%).

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Predicting with confidence and tolerance. (read)

Altman, N. & Krzywinski, M. (2018) Points of significance: Predicting with confidence and tolerance Nature Methods 15:843–844.

Background reading

Krzywinski, M. & Altman, N. (2013) Points of significance: Importance of being uncertain. Nature Methods 10:809–810.

4-day Circos course

Wed 31-10-2018

A 4-day introductory course on genome data parsing and visualization using Circos. Prepared for the Bioinformatics and Genome Analysis course in Institut Pasteur Tunis, Tunis, Tunisia.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Composite of the kinds of images you will learn to make in this course.

Oryza longistaminata genome cake

Mon 24-09-2018

Data visualization should be informative and, where possible, tasty.

Stefan Reuscher from Bioscience and Biotechnology Center at Nagoya University celebrates a publication with a Circos cake.

The cake shows an overview of a de-novo assembled genome of a wild rice species Oryza longistaminata.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Circos cake celebrating Reuscher et al. 2018 publication of the Oryza longistaminata genome.