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art + design
buy artwork Snellen eye chart — mathematical symbols by Martin Krzywinski
VISIONS OF TYPE | Put my typographical posters on your wall. (buy artwork / see all my art)
The 2016 π Day art imagines the digits of Pi as physical masses collapsing under gravity and is featured in the articles The Gravity of Pi and The Boundless Beauty of Pi at the Scientific American [SA Visual blog](http://blogs.scientificamerican.com/sa-visual.
My SnellenMK font adds lowercase and punctuation to the traditional Snellen design.

Visions of Type

1 · Sixteen Ands — Show your love for ampersands

The ampersand originates from the Latin word et, meaning “and” and its form is based on the ligature of ‘e’ and ‘t’. The ampersand used to be the last letter of the English alphabet, which would be recited “... X, Y, Z, and per se and”, with the last phrase slurred to “ampersand”.

buy artwork Sixteen ampersands by Martin Krzywinski
SIXTEEN ANDS | And so on. (buy artwork / see all my art)

Below, sixteen ampersands from different fonts are centered vertically and horizontally. Look how they blend together to reveal a consensus letter.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
SIXTEEN ANDS | Ampersands and ampersands ... and ampersands. (BUY ARTWORK)

2 · Lusting for Ampersands

buy artwork Type peep show: Ampersands by Martin Krzywinski
TYPE PEEP SHOW | Typographical intrigue — see a little, imagine a lot. (buy artwork / see all my art)

To me the ampersand is the letter that I always say yes to.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
TYPE PEEP SHOW | See a little ampers — and imagine a lot. (BUY ARTWORK)
news + thoughts

Cell Genomics cover

Mon 16-01-2023

Our cover on the 11 January 2023 Cell Genomics issue depicts the process of determining the parent-of-origin using differential methylation of alleles at imprinted regions (iDMRs) is imagined as a circuit.

Designed in collaboration with with Carlos Urzua.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Our Cell Genomics cover depicts parent-of-origin assignment as a circuit (volume 3, issue 1, 11 January 2023). (more)

Akbari, V. et al. Parent-of-origin detection and chromosome-scale haplotyping using long-read DNA methylation sequencing and Strand-seq (2023) Cell Genomics 3(1).

Browse my gallery of cover designs.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
A catalogue of my journal and magazine cover designs. (more)

Science Advances cover

Thu 05-01-2023

My cover design on the 6 January 2023 Science Advances issue depicts DNA sequencing read translation in high-dimensional space. The image showss 672 bases of sequencing barcodes generated by three different single-cell RNA sequencing platforms were encoded as oriented triangles on the faces of three 7-dimensional cubes.

More details about the design.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
My Science Advances cover that encodes sequence onto hypercubes (volume 9, issue 1, 6 January 2023). (more)

Kijima, Y. et al. A universal sequencing read interpreter (2023) Science Advances 9

Browse my gallery of cover designs.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
A catalogue of my journal and magazine cover designs. (more)

Regression modeling of time-to-event data with censoring

Mon 21-11-2022

If you sit on the sofa for your entire life, you’re running a higher risk of getting heart disease and cancer. —Alex Honnold, American rock climber

In a follow-up to our Survival analysis — time-to-event data and censoring article, we look at how regression can be used to account for additional risk factors in survival analysis.

We explore accelerated failure time regression (AFTR) and the Cox Proportional Hazards model (Cox PH).

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Regression modeling of time-to-event data with censoring. (read)

Dey, T., Lipsitz, S.R., Cooper, Z., Trinh, Q., Krzywinski, M & Altman, N. (2022) Points of significance: Regression modeling of time-to-event data with censoring. Nature Methods 19.

Music video for Max Cooper's Ascent

Tue 25-10-2022

My 5-dimensional animation sets the visual stage for Max Cooper's Ascent from the album Unspoken Words. I have previously collaborated with Max on telling a story about infinity for his Yearning for the Infinite album.

I provide a walkthrough the video, describe the animation system I created to generate the frames, and show you all the keyframes

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Frame 4897 from the music video of Max Cooper's Asent.

The video recently premiered on YouTube.

Renders of the full scene are available as NFTs.

Gene Cultures exhibit — art at the MIT Museum

Tue 25-10-2022

I am more than my genome and my genome is more than me.

The MIT Museum reopened at its new location on 2nd October 2022. The new Gene Cultures exhibit featured my visualization of the human genome, which walks through the size and organization of the genome and some of the important structures.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
My art at the MIT Museum Gene Cultures exhibit tells shows the scale and structure of the human genome. Pay no attention to the pink chicken.

© 1999–2023 Martin Krzywinski | contact | Canada's Michael Smith Genome Sciences CentreBC Cancer Research CenterBC CancerPHSA