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Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
WELCOME TO THE 5TH DIMENSION | This isn't meant to be understood — it's meant to be enjoyed.
MAX COOPER'S ASCENT | From Max Cooper's album Unspoken Words. Music by Max Cooper. Animation by Martin Krzywinski.
Love music and science? Explore my collaboration with Max Cooper where we tell the story of infinities and animate the digits of π. Both tracks appear on Max's Yearning for the Infinite album.
Another collaboration with Max!

Max Cooper's Ascent — Making of the Music video

Enter the 5th dimension

Ascent answers the question: if you were living in a 5-dimensional room and projected digits of `\pi` onto its walls, what would you see?

1 · Ascend to higher dimensions

We know you're Yearning for the Infinite, but do you yearn for dimensions too?

Welcome to Ascent from Max Cooper's latest album Unspoken Words.

So, go ahead — ascend to higher dimensions. You may forget to come back.

2 · Premiere at the Acropolis

An early version of the Ascent video premiered at Max's Live at the Acropolis show.

ASCENT LIVE AT THE ACROPOLIS | Ascent at Live at the Acropolis Live performance. Music by Max Cooper. Animation by Martin Krzywinski. The final release of the video is slightly different from what was shown at the Acropolis.

The video expands on visual elements first presented at the And& festival in Leuven.

3 · Ascent digital art collection — own a frame

The “Ascent” digital art collection by Max Cooper and Martin Krzywinski comprises vast images of transcendence in 75 million pixels on billboards in NYC, LA, Miami, London, Berlin and Leuven.

The collection is the latest of the NFT collections curated by Mesh Lab.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
MAX COOPER'S ASCENT NFT COLLECTION | ASCENT_Black_1010000001111 (BUY ARTWORK)

They look superb in print.

buy artwork Max Cooper's Ascent (frame 5135) by Martin Krzywinski
MAX COOPER'S ASCENT | Art poster of a full frame of the music video. (buy artwork / see all my art)

4 · Video walkthrough

The video builds on work I did with Max for Transcendence from the Yearning for the Infinite, which itself was based on my 2015 Pi Day art.

The 2015 π Day art takes a Mondrain perspective on π. The art was used in a collaboration with Max Cooper for his track Transcendental Tree Map from the album Yearning for the Infinite. Animation by Nick Cobby and myself. Watch the full show at the Barbican Centre.

In 5 minutes and 55 seconds (8,520 frames), the video takes you from zero to 5 dimensions and back again.

To help you interpret what you are seeing, I walk you through the video. I also present the animation system I built for the video, which was coded from scratch.

The entire animation is built up from about 170 keyframes. Each keyframe defines (a) which objects are shown (b) the dimensionality, size and rotation of each object and (c) the zoom and rotation of the camera itself.

The walkthrough will take you through some of the important keyframes in the video — where new elements are introduced or interesting things happen.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
MAX COOPER'S ASCENT #701 0:29:04 | 5/48 1.c1( 4/ 47)1.c2
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The keyframe definitions are shown in yellow boxes under the frame — these are commands that the animation system parses as it builds the scene over time. The grey boxes show position and zoom of the camera and the actual angles and sizes of objects.

Right now, all this looks confusing — not to worry, it will all be explained in the walkthrough!

5 · My other collaborations with Max

If you like math to a heavy beat and a lot of screen flashing, check out Aleph, our 6 minute video on the story of transfinite numbers.

The video is unique in that it demonstrates Cantor's diagnoal argument to proove that rationals are countable and that reals are not countable.

Love music and science? Explore my collaboration with Max Cooper where we tell the story of infinities and animate the digits of π. Both tracks appear on Max's Yearning for the Infinite album.
Another collaboration with Max!

6 · Mesh lab

Mesh was founded in 2016 to explore the intersection of music, science and art. With a growing global audience and engaged community of practitioners and activists, the platform has conceived work by leading creatives in the fields of music, digital art, film, installation, code, architecture, developing collaborations and commissions with business, arts and science institutions.

Typically, Mesh projects begin with a scientific stimulus which leads to a creative expression, incorporating a variety of digital media including AR, AI, VR, NFT, spatial audio as well as physical structures and live experiences. Collaborators and commissioners include The Babraham Institute, Zaha Hadid Architects, Dolby, L-Acoustics and PepsiCo, and have been exhibited and performances at Barbican Arts Centre, Odeon of Herodes Atticus at the Acropolis and will host an interactive art installation during Art Basel in Miami from 1—2 December.

news + thoughts

Regression modeling of time-to-event data with censoring

Mon 21-11-2022

If you sit on the sofa for your entire life, you’re running a higher risk of getting heart disease and cancer. —Alex Honnold, American rock climber

In a follow-up to our Survival analysis — time-to-event data and censoring article, we look at how regression can be used to account for additional risk factors in survival analysis.

We explore accelerated failure time regression (AFTR) and the Cox Proportional Hazards model (Cox PH).

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Regression modeling of time-to-event data with censoring. (read)

Dey, T., Lipsitz, S.R., Cooper, Z., Trinh, Q., Krzywinski, M & Altman, N. (2022) Points of significance: Regression modeling of time-to-event data with censoring. Nature Methods 19.

Music video for Max Cooper's Ascent

Tue 25-10-2022

My 5-dimensional animation sets the visual stage for Max Cooper's Ascent from the album Unspoken Words. I have previously collaborated with Max on telling a story about infinity for his Yearning for the Infinite album.

I provide a walkthrough the video, describe the animation system I created to generate the frames, and show you all the keyframes

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Frame 4897 from the music video of Max Cooper's Asent.

The video recently premiered on YouTube.

Renders of the full scene are available as NFTs.

Gene Cultures exhibit — art at the MIT Museum

Tue 25-10-2022

I am more than my genome and my genome is more than me.

The MIT Museum reopened at its new location on 2nd October 2022. The new Gene Cultures exhibit featured my visualization of the human genome, which walks through the size and organization of the genome and some of the important structures.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
My art at the MIT Museum Gene Cultures exhibit tells shows the scale and structure of the human genome. Pay no attention to the pink chicken.

Annals of Oncology cover

Wed 14-09-2022

My cover design on the 1 September 2022 Annals of Oncology issue shows 570 individual cases of difficult-to-treat cancers. Each case shows the number and type of actionable genomic alterations that were detected and the length of therapies that resulted from the analysis.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
An organic arrangement of 570 individual cases of difficult-to-treat cancers showing genomic changes and therapies. Apperas on Annals of Oncology cover (volume 33, issue 9, 1 September 2022).

Pleasance E et al. Whole-genome and transcriptome analysis enhances precision cancer treatment options (2022) Annals of Oncology 33:939–949.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
My Annals of Oncology 570 cancer cohort cover (volume 33, issue 9, 1 September 2022). (more)

Browse my gallery of cover designs.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
A catalogue of my journal and magazine cover designs. (more)

Survival analysis—time-to-event data and censoring

Fri 05-08-2022

Love's the only engine of survival. —L. Cohen

We begin a series on survival analysis in the context of its two key complications: skew (which calls for the use of probability distributions, such as the Weibull, that can accomodate skew) and censoring (required because we almost always fail to observe the event in question for all subjects).

We discuss right, left and interval censoring and how mishandling censoring can lead to bias and loss of sensitivity in tests that probe for differences in survival times.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Survival analysis—time-to-event data and censoring. (read)

Dey, T., Lipsitz, S.R., Cooper, Z., Trinh, Q., Krzywinski, M & Altman, N. (2022) Points of significance: Survival analysis—time-to-event data and censoring. Nature Methods 19:906–908.

3,117,275,501 Bases, 0 Gaps

Sun 21-08-2022

See How Scientists Put Together the Complete Human Genome.

My graphic in Scientific American's Graphic Science section in the August 2022 issue shows the full history of the human genome assembly — from its humble shotgun beginnings to the gapless telomere-to-telomere assembly.

Read about the process and methods behind the creation of the graphic.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
3,117,275,501 Bases, 0 Gaps. Text by Clara Moskowitz (Senior Editor), art direction by Jen Christiansen (Senior Graphics Editor), source: UCSC Genome Browser.

See all my Scientific American Graphic Science visualizations.


© 1999–2022 Martin Krzywinski | contact | Canada's Michael Smith Genome Sciences CentreBC Cancer Research CenterBC CancerPHSA