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Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
WELCOME TO THE 5TH DIMENSION | This isn't meant to be understood — it's meant to be enjoyed.
MAX COOPER'S ASCENT | From Max Cooper's album Unspoken Words. Music by Max Cooper. Animation by Martin Krzywinski.
Love music and science? Explore my collaboration with Max Cooper where we tell the story of infinities and animate the digits of π. Both tracks appear on Max's Yearning for the Infinite album.
Another collaboration with Max!

Max Cooper's Ascent — Making of the Music video

Enter the 5th dimension

Ascent answers the question: if you were living in a 5-dimensional room and projected digits of `\pi` onto its walls, what would you see?

1 · Ascend to higher dimensions

We know you're Yearning for the Infinite, but do you yearn for dimensions too?

Welcome to Ascent from Max Cooper's latest album Unspoken Words.

So, go ahead — ascend to higher dimensions. You may forget to come back.

2 · Premiere at the Acropolis

An early version of the Ascent video premiered at Max's Live at the Acropolis show.

ASCENT LIVE AT THE ACROPOLIS | Ascent at Live at the Acropolis Live performance. Music by Max Cooper. Animation by Martin Krzywinski. The final release of the video is slightly different from what was shown at the Acropolis.

The video expands on visual elements first presented at the And& festival in Leuven.

3 · Ascent digital art collection — own a frame

The “Ascent” digital art collection by Max Cooper and Martin Krzywinski comprises vast images of transcendence in 75 million pixels on billboards in NYC, LA, Miami, London, Berlin and Leuven.

The collection is the latest of the NFT collections curated by Mesh Lab.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca buy artwork
MAX COOPER'S ASCENT NFT COLLECTION | ASCENT_Black_1010000001111 (BUY ARTWORK)

They look superb in print.

buy artwork Max Cooper's Ascent (frame 5135) by Martin Krzywinski
MAX COOPER'S ASCENT | Art poster of a full frame of the music video. (buy artwork / see all my art)

4 · Video walkthrough

The video builds on work I did with Max for Transcendence from the Yearning for the Infinite, which itself was based on my 2015 Pi Day art.

The 2015 π Day art takes a Mondrain perspective on π. The art was used in a collaboration with Max Cooper for his track Transcendental Tree Map from the album Yearning for the Infinite. Animation by Nick Cobby and myself. Watch the full show at the Barbican Centre.

In 5 minutes and 55 seconds (8,520 frames), the video takes you from zero to 5 dimensions and back again.

To help you interpret what you are seeing, I walk you through the video. I also present the animation system I built for the video, which was coded from scratch.

The entire animation is built up from about 170 keyframes. Each keyframe defines (a) which objects are shown (b) the dimensionality, size and rotation of each object and (c) the zoom and rotation of the camera itself.

The walkthrough will take you through some of the important keyframes in the video — where new elements are introduced or interesting things happen.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
MAX COOPER'S ASCENT #701 0:29:04 | 5/48 1.c1( 4/ 47)1.c2
1.c1
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c c0 s [w] 0.815
c c0 s [xyz] 0.15
1.c2
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view
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zoom
1
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C0
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0.15
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edge
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The keyframe definitions are shown in yellow boxes under the frame — these are commands that the animation system parses as it builds the scene over time. The grey boxes show position and zoom of the camera and the actual angles and sizes of objects.

Right now, all this looks confusing — not to worry, it will all be explained in the walkthrough!

5 · My other collaborations with Max

If you like math to a heavy beat and a lot of screen flashing, check out Aleph, our 6 minute video on the story of transfinite numbers.

The video is unique in that it demonstrates Cantor's diagnoal argument to proove that rationals are countable and that reals are not countable.

Love music and science? Explore my collaboration with Max Cooper where we tell the story of infinities and animate the digits of π. Both tracks appear on Max's Yearning for the Infinite album.
Another collaboration with Max!

6 · Mesh lab

Mesh was founded in 2016 to explore the intersection of music, science and art. With a growing global audience and engaged community of practitioners and activists, the platform has conceived work by leading creatives in the fields of music, digital art, film, installation, code, architecture, developing collaborations and commissions with business, arts and science institutions.

Typically, Mesh projects begin with a scientific stimulus which leads to a creative expression, incorporating a variety of digital media including AR, AI, VR, NFT, spatial audio as well as physical structures and live experiences. Collaborators and commissioners include The Babraham Institute, Zaha Hadid Architects, Dolby, L-Acoustics and PepsiCo, and have been exhibited and performances at Barbican Arts Centre, Odeon of Herodes Atticus at the Acropolis and will host an interactive art installation during Art Basel in Miami from 1—2 December.

news + thoughts

Convolutional neural networks

Thu 17-08-2023

Nature uses only the longest threads to weave her patterns, so that each small piece of her fabric reveals the organization of the entire tapestry. – Richard Feynman

Following up on our Neural network primer column, this month we explore a different kind of network architecture: a convolutional network.

The convolutional network replaces the hidden layer of a fully connected network (FCN) with one or more filters (a kind of neuron that looks at the input within a narrow window).

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Convolutional neural networks. (read)

Even through convolutional networks have far fewer neurons that an FCN, they can perform substantially better for certain kinds of problems, such as sequence motif detection.

Derry, A., Krzywinski, M & Altman, N. (2023) Points of significance: Convolutional neural networks. Nature Methods 20:.

Background reading

Derry, A., Krzywinski, M. & Altman, N. (2023) Points of significance: Neural network primer. Nature Methods 20:165–167.

Lever, J., Krzywinski, M. & Altman, N. (2016) Points of significance: Logistic regression. Nature Methods 13:541–542.

Neural network primer

Tue 10-01-2023

Nature is often hidden, sometimes overcome, seldom extinguished. —Francis Bacon

In the first of a series of columns about neural networks, we introduce them with an intuitive approach that draws from our discussion about logistic regression.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Neural network primer. (read)

Simple neural networks are just a chain of linear regressions. And, although neural network models can get very complicated, their essence can be understood in terms of relatively basic principles.

We show how neural network components (neurons) can be arranged in the network and discuss the ideas of hidden layers. Using a simple data set we show how even a 3-neuron neural network can already model relatively complicated data patterns.

Derry, A., Krzywinski, M & Altman, N. (2023) Points of significance: Neural network primer. Nature Methods 20:165–167.

Background reading

Lever, J., Krzywinski, M. & Altman, N. (2016) Points of significance: Logistic regression. Nature Methods 13:541–542.

Cell Genomics cover

Mon 16-01-2023

Our cover on the 11 January 2023 Cell Genomics issue depicts the process of determining the parent-of-origin using differential methylation of alleles at imprinted regions (iDMRs) is imagined as a circuit.

Designed in collaboration with with Carlos Urzua.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Our Cell Genomics cover depicts parent-of-origin assignment as a circuit (volume 3, issue 1, 11 January 2023). (more)

Akbari, V. et al. Parent-of-origin detection and chromosome-scale haplotyping using long-read DNA methylation sequencing and Strand-seq (2023) Cell Genomics 3(1).

Browse my gallery of cover designs.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
A catalogue of my journal and magazine cover designs. (more)

Science Advances cover

Thu 05-01-2023

My cover design on the 6 January 2023 Science Advances issue depicts DNA sequencing read translation in high-dimensional space. The image showss 672 bases of sequencing barcodes generated by three different single-cell RNA sequencing platforms were encoded as oriented triangles on the faces of three 7-dimensional cubes.

More details about the design.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
My Science Advances cover that encodes sequence onto hypercubes (volume 9, issue 1, 6 January 2023). (more)

Kijima, Y. et al. A universal sequencing read interpreter (2023) Science Advances 9.

Browse my gallery of cover designs.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
A catalogue of my journal and magazine cover designs. (more)

Regression modeling of time-to-event data with censoring

Thu 17-08-2023

If you sit on the sofa for your entire life, you’re running a higher risk of getting heart disease and cancer. —Alex Honnold, American rock climber

In a follow-up to our Survival analysis — time-to-event data and censoring article, we look at how regression can be used to account for additional risk factors in survival analysis.

We explore accelerated failure time regression (AFTR) and the Cox Proportional Hazards model (Cox PH).

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Regression modeling of time-to-event data with censoring. (read)

Dey, T., Lipsitz, S.R., Cooper, Z., Trinh, Q., Krzywinski, M & Altman, N. (2022) Points of significance: Regression modeling of time-to-event data with censoring. Nature Methods 19:1513–1515.

Music video for Max Cooper's Ascent

Tue 25-10-2022

My 5-dimensional animation sets the visual stage for Max Cooper's Ascent from the album Unspoken Words. I have previously collaborated with Max on telling a story about infinity for his Yearning for the Infinite album.

I provide a walkthrough the video, describe the animation system I created to generate the frames, and show you all the keyframes

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Frame 4897 from the music video of Max Cooper's Asent.

The video recently premiered on YouTube.

Renders of the full scene are available as NFTs.


© 1999–2023 Martin Krzywinski | contact | Canada's Michael Smith Genome Sciences CentreBC Cancer Research CenterBC CancerPHSA