The first Points of View column was about color coding in the July 2010 issue of Nature Methods. In its 5 year history, the column has established a significant legacy— it is one of the most frequently accessed parts of Nature Methods. The community sees the value in clear and effective visual communication and acknowledges the need for a forum in which best practices in the field are presented practically and accessibly.
Bang Wong, in collaboration with visiting authors (Noam Shoresh, Nils Gehlenborg, Cydney Nielsen and Rikke Schmidt Kjærgaard), has penned 29 columns in the period of August 2010 to December 2012, covering broad topics such as salience, Gestalt principles, color, typography, negative space, layout, and data integration.
The announcement of the return of the column, together with its history and a description of me, the new author, are available at the Nature Methods methagora blog. Humor is kept by repeated reference to my now-dead-but-once-famous pet rat.
When it was A.C. Greyling's turn to speak at a debate in which Christopher Hitchens and Richard Dawkins already made their points, Greyling said
When one gets up to speak this late in a debate, one is a bit tempated to quote that Hungarian M.P. who after a long, long, long discussion in the parliament in Budapest stood up and said, "Everything has been said but not everybody said it yet." (watch on YouTube)
Indeed, this is quite how I feel after being offered to be the new author of Nature Methods Point of View column. Both Bang and Hitchens provide significant inspiration for me, so Greyling's words are particularly fitting.
To improve on the column is impossible. My challenge is to identify useful topics that have not yet been covered. I will be working closely with Nature Methods and Bang to ensure that the columns strike the right balance of topic, tone and timbre.
In 2013 the Points of View column spawned the Points of Significance column, which deals with statistics in biological science.
For the month of August 2013, the entire set of 35 columns is available for free.
The column continues to run, though no longer monthly.
A PDF eBook of the 38 Points of View articles published between August 2010 and February 2015 is now available at the Nature Shop for $7.99 under the title Visual strategies for biological data: the collected Points of View.
Data visualization should be informative and, where possible, tasty.
Stefan Reuscher from Bioscience and Biotechnology Center at Nagoya University celebrates a publication with a Circos cake.
The cake shows an overview of a de-novo assembled genome of a wild rice species Oryza longistaminata.
The presence of constraints in experiments, such as sample size restrictions, awkward blocking or disallowed treatment combinations may make using classical designs very difficult or impossible.
Optimal design is a powerful, general purpose alternative for high quality, statistically grounded designs under nonstandard conditions.
We discuss two types of optimal designs (D-optimal and I-optimal) and show how it can be applied to a scenario with sample size and blocking constraints.
Smucker, B., Krzywinski, M. & Altman, N. (2018) Points of significance: Optimal experimental design Nature Methods 15:599–600.
Krzywinski, M., Altman, N. (2014) Points of significance: Two factor designs. Nature Methods 11:1187–1188.
Krzywinski, M. & Altman, N. (2014) Points of significance: Analysis of variance (ANOVA) and blocking. Nature Methods 11:699–700.
Krzywinski, M. & Altman, N. (2014) Points of significance: Designing comparative experiments. Nature Methods 11:597–598.
An illustration of the Tree of Life, showing some of the key branches.
The tree is drawn as a DNA double helix, with bases colored to encode ribosomal RNA genes from various organisms on the tree.
All living things on earth descended from a single organism called LUCA (last universal common ancestor) and inherited LUCA’s genetic code for basic biological functions, such as translating DNA and creating proteins. Constant genetic mutations shuffled and altered this inheritance and added new genetic material—a process that created the diversity of life we see today. The “tree of life” organizes all organisms based on the extent of shuffling and alteration between them. The full tree has millions of branches and every living organism has its own place at one of the leaves in the tree. The simplified tree shown here depicts all three kingdoms of life: bacteria, archaebacteria and eukaryota. For some organisms a grey bar shows when they first appeared in the tree in millions of years (Ma). The double helix winding around the tree encodes highly conserved ribosomal RNA genes from various organisms.
Johnson, H.L. (2018) The Whole Earth Cataloguer, Sactown, Jun/Jul, p. 89
An article about keyboard layouts and the history and persistence of QWERTY.
McDonald, T. (2018) Why we can't give up this odd way of typing, BBC, 25 May 2018.
I've previously taken a more fine-art approach to cover design, such for those of Nature, Genome Research and Trends in Genetics. I've used microscopy images to create a cover for PNAS—the one that made biology look like astrophysics—and thought that this is kind of material I'd start with for the MCS cover.