Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca - contact me Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca on Twitter Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca - Lumondo Photography Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca - Pi Art Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca - Hilbertonians - Creatures on the Hilbert CurveMartin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca - Pi Day 2020 - Piku
I'm not real and I deny I won't heal unless I cry.Cocteau Twinslet it gomore quotes

Scientific graphical abstracts — design guidelines


fun + amusement

Dummer — Like Nothing Else


The Hummer font is a slightly modified Antique Olive Nord. The Like Nothing Else tag line is Trade Gothic. Both have character widths increased to 110-120% and individually adjusted kerning. Get the Illustrator CS5 file for both logos.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Hummer logo. (EPS, PNG)
Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Dummer logo. (EPS, PNG)
Download high-resolution images.

This project might give you the impression that I don't like Hummers. You'd be right.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
It could be worse. But not by much. (zoom)
Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
It could be worse. But not by much. (zoom)
Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
It could be worse. But not by much. (zoom)

update

The Maurauder. Over 25,000 lb — five times what an H3 weighs. Enough said.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
There is always someone with a bigger one. (Manufacturer's page.)

Dummer - Like Nothing Else

Hummers are a cultural equivalent of a toxic warning label and have the same effect on me as bug spray on mosquitoes.

I am not the first one to satirize this automotive aberration, so there's some hope.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Dummer. Like Nothing Else. (New York Times — Laugh Lines)

GM's advertisement images require no modification for the satire, which makes it all that much better.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Dumb and Dumber. (New York Times — Laugh Lines)

I could have just as well used the Lincoln Navigator or Cadillac Escalade, but they don't embody the superlative like the Hummer.

The Hummer brand proved itself to be aesthetically, rationally and economically unsustainable and collapsed after a failed attempt to sell it to China. There continues to be a robust market for used Hummers. Let the farce continue.

I'm hated

It delights me that this project produced my first hate mail.

I want to meet Doug and give him a hug for adding another dimension to this project.

I'm loved

The images got picked up by the New York Times laughlines blog, which drew a couple of fan mails.

But neither made me feel as good as Doug's email.

Dummer Images

Dummer. Like nothing else. A pretty good Hummer satire. / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Dummer. Like nothing else. (zoom)
Dummer. Like nothing else. A pretty good Hummer satire. / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Dummer. Like nothing else. (zoom)
Dummer. Like nothing else. A pretty good Hummer satire. / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Dummer. Like nothing else. (zoom)
Dummer. Like nothing else. A pretty good Hummer satire. / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Dummer. Like nothing else. (zoom)
Dummer. Like nothing else. A pretty good Hummer satire. / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Dummer. Like nothing else. (zoom)
Dummer. Like nothing else. A pretty good Hummer satire. / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Dummer. Like nothing else. (zoom)
Dummer. Like nothing else. A pretty good Hummer satire. / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Dummer. Like nothing else. (zoom)
Dummer. Like nothing else. A pretty good Hummer satire. / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Dummer. Like nothing else. (zoom)
Dummer. Like nothing else. A pretty good Hummer satire. / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Dummer. Like nothing else. (zoom)

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news + thoughts

Music for the Moon: Flunk's 'Down Here / Moon Above'

Sat 29-05-2021

The Sanctuary Project is a Lunar vault of science and art. It includes two fully sequenced human genomes, sequenced and assembled by us at Canada's Michael Smith Genome Sciences Centre.

The first disc includes a song composed by Flunk for the (eventual) trip to the Moon.

But how do you send sound to space? I describe the inspiration, process and art behind the work.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
The song 'Down Here / Moon Above' from Flunk's new album History of Everything Ever is our song for space. It appears on the Sanctuary genome discs, which aim to send two fully sequenced human genomes to the Moon. (more)

Browse the genome discs.

Happy 2021 `\pi` Day—
A forest of digits

Sun 14-03-2021

Celebrate `\pi` Day (March 14th) and finally see the digits through the forest.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
The 26th tree in the digit forest of `\pi`. Why is there a flower on the ground?. (details)

This year is full of botanical whimsy. A Lindenmayer system forest – deterministic but always changing. Feel free to stop and pick the flowers from the ground.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
The first 46 digits of `\pi` in 8 trees. There are so many more. (details)

And things can get crazy in the forest.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
A forest of the digits of '\pi`, by ecosystem. (details)

Check out art from previous years: 2013 `\pi` Day and 2014 `\pi` Day, 2015 `\pi` Day, 2016 `\pi` Day, 2017 `\pi` Day, 2018 `\pi` Day and 2019 `\pi` Day.

Testing for rare conditions

Sun 30-05-2021

All that glitters is not gold. —W. Shakespeare

The sensitivity and specificity of a test do not necessarily correspond to its error rate. This becomes critically important when testing for a rare condition — a test with 99% sensitivity and specificity has an even chance of being wrong when the condition prevalence is 1%.

We discuss the positive predictive value (PPV) and how practices such as screen can increase it.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Testing for rare conditions. (read)

Altman, N. & Krzywinski, M. (2021) Points of significance: Testing for rare conditions. Nature Methods 18:224–225.

Standardization fallacy

Tue 09-02-2021

We demand rigidly defined areas of doubt and uncertainty! —D. Adams

A popular notion about experiments is that it's good to keep variability in subjects low to limit the influence of confounding factors. This is called standardization.

Unfortunately, although standardization increases power, it can induce unrealistically low variability and lead to results that do not generalize to the population of interest. And, in fact, may be irreproducible.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Standardization fallacy. (read)

Not paying attention to these details and thinking (or hoping) that standardization is always good is the "standardization fallacy". In this column, we look at how standardization can be balanced with heterogenization to avoid this thorny issue.

Voelkl, B., Würbel, H., Krzywinski, M. & Altman, N. (2021) Points of significance: Standardization fallacy. Nature Methods 18:5–6.