Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / - contact me Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / on Twitter Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / - Lumondo Photography Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / - Pi Art Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / - Hilbertonians - Creatures on the Hilbert CurveMartin Krzywinski / Canada's Michael Smith Genome Sciences Centre / - Pi Day 2020 - Piku
Safe, fallen down this way, I want to be just what I am.Cocteau Twinssafe at lastmore quotes

compassion: important

Scientific graphical abstracts — design guidelines

outbreak + poetry

Martin Krzywinski @MKrzywinski
The 2020 Pi Day art celebrates the digits of `\pi` with piku (パイク) —poetry inspired by haiku.
They serve as the form for The Outbreak Poems.

The Outbreak Poems

Short emissions from piku actual during the coronavirus outbreak. Not just the pandemic, but also about other feelings. As they come.

Explore the collection by themes such as life, light, day, night, time, thought.

If you don't know how to feel about that, refer to my tree of emotional life.

The Outbreak Poems are piku.

A piku (`\pi`ku, パイク) is a poem whose line syllable count is based on the first three digits of `\pi`. Piku were created to celebrate the 2020 Pi Day.

I don't as much write piku as feel them, then filtered through a frosted window they come out as words.

Recently I've added comments to piku as I write them. Notes to (on) self.

latest outbreak poems

Wednesday, 19 May 2021

3 Your hours
1 will
4 last me my years.

3 Hole in heart
1 is
4 bigger than you
1 were.

3 From hand to
1 heart
4 in a flutter.

3 Come fly in
1 my
4 heart for a while.

3 Can't feel you
1 in
4 my hand, dying.

3 Need new words,
1 please,
4 for these feelings.

3 Mini dee
1 you
4 put you in me.
Mindy was a chickadee. And then she wasn't.

Read all past poems.


news + thoughts

Music for the Moon: Flunk's 'Down Here / Moon Above'

Sat 29-05-2021

The Sanctuary Project is a Lunar vault of science and art. It includes two fully sequenced human genomes, sequenced and assembled by us at Canada's Michael Smith Genome Sciences Centre.

The first disc includes a song composed by Flunk for the (eventual) trip to the Moon.

But how do you send sound to space? I describe the inspiration, process and art behind the work.

Martin Krzywinski @MKrzywinski
The song 'Down Here / Moon Above' from Flunk's new album History of Everything Ever is our song for space. It appears on the Sanctuary genome discs, which aim to send two fully sequenced human genomes to the Moon. (more)

Browse the genome discs.

Happy 2021 `\pi` Day—
A forest of digits

Sun 14-03-2021

Celebrate `\pi` Day (March 14th) and finally see the digits through the forest.

Martin Krzywinski @MKrzywinski
The 26th tree in the digit forest of `\pi`. Why is there a flower on the ground?. (details)

This year is full of botanical whimsy. A Lindenmayer system forest – deterministic but always changing. Feel free to stop and pick the flowers from the ground.

Martin Krzywinski @MKrzywinski
The first 46 digits of `\pi` in 8 trees. There are so many more. (details)

And things can get crazy in the forest.

Martin Krzywinski @MKrzywinski
A forest of the digits of '\pi`, by ecosystem. (details)

Check out art from previous years: 2013 `\pi` Day and 2014 `\pi` Day, 2015 `\pi` Day, 2016 `\pi` Day, 2017 `\pi` Day, 2018 `\pi` Day and 2019 `\pi` Day.

Testing for rare conditions

Sun 30-05-2021

All that glitters is not gold. —W. Shakespeare

The sensitivity and specificity of a test do not necessarily correspond to its error rate. This becomes critically important when testing for a rare condition — a test with 99% sensitivity and specificity has an even chance of being wrong when the condition prevalence is 1%.

We discuss the positive predictive value (PPV) and how practices such as screen can increase it.

Martin Krzywinski @MKrzywinski
Nature Methods Points of Significance column: Testing for rare conditions. (read)

Altman, N. & Krzywinski, M. (2021) Points of significance: Testing for rare conditions. Nature Methods 18:224–225.

Standardization fallacy

Tue 09-02-2021

We demand rigidly defined areas of doubt and uncertainty! —D. Adams

A popular notion about experiments is that it's good to keep variability in subjects low to limit the influence of confounding factors. This is called standardization.

Unfortunately, although standardization increases power, it can induce unrealistically low variability and lead to results that do not generalize to the population of interest. And, in fact, may be irreproducible.

Martin Krzywinski @MKrzywinski
Nature Methods Points of Significance column: Standardization fallacy. (read)

Not paying attention to these details and thinking (or hoping) that standardization is always good is the "standardization fallacy". In this column, we look at how standardization can be balanced with heterogenization to avoid this thorny issue.

Voelkl, B., Würbel, H., Krzywinski, M. & Altman, N. (2021) Points of significance: Standardization fallacy. Nature Methods 18:5–6.

Graphical Abstract Design Guidelines

Fri 13-11-2020

Clear, concise, legible and compelling.

Making a scientific graphical abstract? Refer to my practical design guidelines and redesign examples to improve organization, design and clarity of your graphical abstracts.

Martin Krzywinski @MKrzywinski
Graphical Abstract Design Guidelines — Clear, concise, legible and compelling.

"This data might give you a migrane"

Tue 06-10-2020

An in-depth look at my process of reacting to a bad figure — how I design a poster and tell data stories.

Martin Krzywinski @MKrzywinski
A poster of high BMI and obesity prevalence for 185 countries.