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Answers, anytime

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1 · We have answers for you

Do you want free answers to your problems presented in a clear and concise manner? Read on.

It doesn't matter whether you're arguing with your partner, friend, pet, or yourself. We can help.

Simply put: we provide answers to your problems.

How do we do it? Through our insightful knowledge of

  • different types of problems
  • different types of answers
  • linear congruent method

we can confidently present an answer to your questions. It's hard to believe, I know!

The best part? Well, other than the right answers, of course. Our service is free! We provide answers at absolutely no charge. We don't want your money — we want you on your way with an answer in hand.

1.1 · What can I expect?

Why, answers of course. Your answer will appear in the following form

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca

The correct course of action (YES, NO or MAYBE) will be presented one of many style.

1.2 · Can I trust the answer

We're confident that our answers are 100% correct.

Just read this testimonial — others have already been answered. You can be be next!

Our grandfather was in a coma. I asked your site whether we should pull the life support and got a 'yes'. Roger passed away in peace. Thank you for putting us at ease during the process.
—Carrie H

1.3 · I'm ready for the answer

Be prepared, though. Using our service may lead you down the correct road quickly, efficiently and with time to spare. You may be surprised.

When you're ready, focus on the question you want to have solved and hit the I WANT AN ANSWER button above.

1.4 · I already got an answer

Congratulations! Use it well.

1.5 · I need more answers

Don't we all. You can obtain an answer every 5 minutes.

Even if it feels like you can't wait — you can.

2 · Our method

Finding answers to your problems — that's what we do.

It's not easy, especially when you consider the variety of problems we deal with.

That's why we use the linear congruent method in computing answers. Without burdening you with technicalities (those mathematicians sure like to make things sound complicated!), we have selected this method because

  • the linear congruent method scales favourably with the number of problems — we can answer many problems without investing in expensive hardware
  • “linear” is a common synonym for “straight”. We give you the straight answer.
  • it is “congruent”, meaning that it corresponds to the right answer.

3 · Our service

We provide answers to you free of charge. Our rewards come from solving your problems — every time.

So far, we have generated 294 answers. Each one as correct as the next.

Below is a sample answer. Do not use this answer to solve a problem. If you want a real answer, hit the I WANT AN ANSWER button above.

news + thoughts

Neural network primer

Mon 06-02-2023

Nature is often hidden, sometimes overcome, seldom extinguished. —Francis Bacon

In the first of a series of columns about neural networks, we introduce them with an intuitive approach that draws from our discussion about logistic regression.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Neural network primer. (read)

Simple neural networks are just a chain of linear regressions. And, although neural network models can get very complicated, their essence can be understood in terms of relatively basic principles.

We show how neural network components (neurons) can be arranged in the network and discuss the ideas of hidden layers. Using a simple data set we show how even a 3-neuron neural network can already model relatively complicated data patterns.

Derry, A., Krzywinski, M & Altman, N. (2023) Points of significance: Neural network primer. Nature Methods 20.

Background reading

Lever, J., Krzywinski, M. & Altman, N. (2016) Points of significance: Logistic regression. Nature Methods 13:541–542.

Cell Genomics cover

Mon 16-01-2023

Our cover on the 11 January 2023 Cell Genomics issue depicts the process of determining the parent-of-origin using differential methylation of alleles at imprinted regions (iDMRs) is imagined as a circuit.

Designed in collaboration with with Carlos Urzua.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Our Cell Genomics cover depicts parent-of-origin assignment as a circuit (volume 3, issue 1, 11 January 2023). (more)

Akbari, V. et al. Parent-of-origin detection and chromosome-scale haplotyping using long-read DNA methylation sequencing and Strand-seq (2023) Cell Genomics 3(1).

Browse my gallery of cover designs.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
A catalogue of my journal and magazine cover designs. (more)

Science Advances cover

Thu 05-01-2023

My cover design on the 6 January 2023 Science Advances issue depicts DNA sequencing read translation in high-dimensional space. The image showss 672 bases of sequencing barcodes generated by three different single-cell RNA sequencing platforms were encoded as oriented triangles on the faces of three 7-dimensional cubes.

More details about the design.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
My Science Advances cover that encodes sequence onto hypercubes (volume 9, issue 1, 6 January 2023). (more)

Kijima, Y. et al. A universal sequencing read interpreter (2023) Science Advances 9.

Browse my gallery of cover designs.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
A catalogue of my journal and magazine cover designs. (more)

© 1999–2023 Martin Krzywinski | contact | Canada's Michael Smith Genome Sciences CentreBC Cancer Research CenterBC CancerPHSA