Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca - contact me Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca on Twitter Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca - Lumondo Photography Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca - Pi Art Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca - Hilbertonians - Creatures on the Hilbert CurveMartin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca - Pi Day 2020 - Piku
Where am I supposed to go? Where was I supposed to know?Violet Indianaget lost in questionsmore quotes

The Outbreak Poems — artistic emissions in a pandemic


language + fiction

Dark Matter of the English Language—the unwords

Words are easy, like the wind;
Faithful friends are hard to find.
—William Shakespeare

unanimals

Critters that definitely don't exist but, perhaps, should.

The backal is probably a feisty biter while the cakmiran probably has a quizzical look. And I would completely avoid the fangol—he sounds like trouble.

A great exercise for kids and the comedic-at-heart would be to try to draw some of these. What would a gakrin look like? Or a gorderish?

Below are the alphabetically first 4–10 letter single-word unanimals for each letter. In some cases, no names of a given length were generated for a given letter.

—4—
aytt
bebe
bick
caen
calb
dalh
dlol
fibl
file
galg
gaon
haen
hale
ilpa
jang
kall
laot
laro
mard
mean
naal
neat
orot
oton
pate
peof
qaid
radc
ranl
saol
shal
tial
walr
weil
—5—
acter
alome
boloo
brata
cabal
capir
dacwo
daxol
fimat
fogon
gatey
geass
haore
heisa
ihire
kardo
kouse
lalpy
lante
malbe
morci
nlreg
nriwe
oacda
omita
paric
ponga
radka
ramep
saage
saako
teart
ufuse
wease
weatl
—6—
acukoe
agtalt
backal
banher
caidat
calepe
dearle
dolpin
eyrita
fangol
gafala
gakrin
haamet
hadnel
iykile
jacang
kagcet
kurdot
lalper
largoz
mamket
mander
narnla
oammim
ooceat
palyus
patble
rarman
ravlil
seaise
seikol
tarbaa
tonele
usrenl
valiss
waatir
whagit
—7—
amreron
apunaed
baadber
balsidd
cadtole
calfasf
daldaug
dalfiso
eolgeal
eomrarf
fondard
gallish
gamymly
hankrer
hokloru
itarato
jatfish
jatwoss
kaister
lamushe
leittoy
madarle
malfash
narddco
nhucasf
oncigut
ootfoto
pakline
parcata
qicsoor
raacbor
raipins
sablrod
sabrilr
tenlrit
tonmede
vansoar
vatkifh
waldfil
walslil
—8—
anlonfow
arnbwict
baieslel
barnnkor
caeffuse
cakmiran
disteale
erhadiol
geepbuwl
golshowo
halalale
hocscist
loicpalt
lruzgind
mannforl
marppuse
obberose
oosgerle
pandleie
perphist
raaldope
ragprerd
saelling
saistiet
tolrfish
valcunle
wadmfish
wasshail
—9—
anlfilher
beigartal
cacdockud
cagccride
gardefand
gorderish
ipilfoyor
keosildor
laechinee
lhallaeye
malpandie
maltreuge
okrerblon
pallanmer
penrhapor
shipopish
shorgeone
ugoflifes
waadarall
waamesder
—10—
asdrosquod
cackemorel
canzlitbar
gaotemtirh
gorofoshew
hirkaflarl
honkerfosh
mapobanadl
moalarfesg
nearretlee
qoarrorule
raccistech
sancockese
sealdhicnh
waagelidhe
weendefish
—11—
condlidilin
cotarleweer
galafonllar
geatingtink
rellswobgry
soridioatar
wolfendelad

Here are all some lists with common suffixes

*ish camfish gallish gawlish gohfish gurrish jatfish mipkish polmish wamfish gorderish shipopish slarmish soulfish tolrfish wadmfish weendefish

*ile halile iykile weadnrile cragiile file gile

*ale anmale calilale disteale halalale hale saale

*use bampuse caeffuse marppuse kouse ufuse

*her banher coocher lorsher anlfilher wher

*tar codtar mistar soridioatar wortautar

*ole rorole cadtole wurkole cole

*ise seaise shoise guceyrise

VIEW ALL

news + thoughts

The SEIRS model for infectious disease dynamics

Thu 18-06-2020

Realistic models of epidemics account for latency, loss of immunity, births and deaths.

We continue with our discussion about epidemic models and show how births, deaths and loss of immunity can create epidemic waves—a periodic fluctuation in the fraction of population that is infected.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: The SEIRS model for infectious disease dynamics. (read)

This column has an interactive supplemental component (download code) that allows you to explore epidemic waves and introduces the idea of the phase plane, a compact way to understand the evolution of an epidemic over its entire course.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: The SEIRS model for infectious disease dynamics. (Interactive supplemental materials)

Bjørnstad, O.N., Shea, K., Krzywinski, M. & Altman, N. (2020) Points of significance: The SEIRS model for infectious disease dynamics. Nature Methods 17:557–558.

Background reading

Bjørnstad, O.N., Shea, K., Krzywinski, M. & Altman, N. (2020) Points of significance: Modeling infectious epidemics. Nature Methods 17:455–456.

Gene Machines

Fri 05-06-2020

Shifting soundscapes, textures and rhythmic loops produced by laboratory machines.

In commemoration of the 20th anniversary of Canada's Michael Smith Genome Sciences Centre, Segue was commissioned to create an original composition based on audio recordings from the GSC's laboratory equipment, robots and computers—to make “music” from the noise they produce.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Gene Machines by Segue. Now available on vinyl.

Virus Mutations Reveal How COVID-19 Really Spread

Mon 01-06-2020

Genetic sequences of the coronavirus tell story of when the virus arrived in each country and where it came from.

Our graphic in Scientific American's Graphic Science section in the June 2020 issue shows a phylogenetic tree based on a snapshot of the data model from Nextstrain as of 31 March 2020.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Virus Mutations Reveal How COVID-19 Really Spread. Text by Mark Fischetti (Senior Editor), art direction by Jen Christiansen (Senior Graphics Editor), source: Nextstrain (enabled by data from GISAID).

Cover of Nature Cancer April 2020

Mon 27-04-2020

Our design on the cover of Nature Cancer's April 2020 issue shows mutation spectra of patients from the POG570 cohort of 570 individuals with advanced metastatic cancer.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Each ellipse system represents the mutation spectrum of an individual patient. Individual ellipses in the system correspond to the number of base changes in a given class and are layered by mutation count. Ellipse angle is controlled by the proportion of mutations in a class within the sample and its size is determined by a sigmoid mapping of mutation count scaled within the layer. The opacity of each system represents the duration since the diagnosis of advanced disease. (read more)

The cover design accompanies our report in the issue Pleasance, E., Titmuss, E., Williamson, L. et al. (2020) Pan-cancer analysis of advanced patient tumors reveals interactions between therapy and genomic landscapes. Nat Cancer 1:452–468.

Modeling infectious epidemics

Tue 16-06-2020

Every day sadder and sadder news of its increase. In the City died this week 7496; and of them, 6102 of the plague. But it is feared that the true number of the dead this week is near 10,000 ....
—Samuel Pepys, 1665

This month, we begin a series of columns on epidemiological models. We start with the basic SIR model, which models the spread of an infection between three groups in a population: susceptible, infected and recovered.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Modeling infectious epidemics. (read)

We discuss conditions under which an outbreak occurs, estimates of spread characteristics and the effects that mitigation can play on disease trajectories. We show the trends that arise when "flattenting the curve" by decreasing `R_0`.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Modeling infectious epidemics. (read)

This column has an interactive supplemental component (download code) that allows you to explore how the model curves change with parameters such as infectious period, basic reproduction number and vaccination level.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Modeling infectious epidemics. (Interactive supplemental materials)

Bjørnstad, O.N., Shea, K., Krzywinski, M. & Altman, N. (2020) Points of significance: Modeling infectious epidemics. Nature Methods 17:455–456.

The Outbreak Poems

Sat 04-04-2020

I'm writing poetry daily to put my feelings into words more often during the COVID-19 outbreak.

Tears decline
the
plural of sad.
Souls look out
from
dark eye windows.

Read the poems and learn what a piku is.