Feel the vibe, feel the terror, feel the painMad about you, orchestrally.more quotes
very clickable
data visualization + art
THE ENTIRE UNIVERSE | Put it on your wall. (buy artwork / see all my art)
If you like space, you will love this. The 2017 π Day art imagines the digits of π as a star catalogue with constellations of extinct animals and plants. The work is featured in the article Pi in the Sky at the Scientific American SA Visual blog.
If you like space, you'll love my the 12,000 billion light-year map of clusters, superclusters and voids. Find the biggest nothings in Boötes and Eridanus.The largest map there is shows the location of voids and galaxy superclusters in our visible universe.

null
from an undefined
place,
undefined
create (a place)
an account
of us
— Viorica Hrincu

Sometimes when you stare at the void, the void sends you a poem.

# Universe—Superclusters and Voids

The Universe — Superclustesr and Voids. The two supergalactic hemispheres showing Abell clusters (blue), superclusters (magenta) and voids (black) within a distance of 6,000 million light-years from the Milky Way.

The average density of the universe is about $10 \times 10^{-30} \text{ g/cm}^3$ or about 6 protons per cubic meter. This should put some perspective in what we mean when we speak about voids as "underdense regions".

listen: there's a hell
of a good universe next door; let's go
—e.e. cummings (pity this monster, manunkind)

# designing the poster

## 1 · Evolution of the Superclusters and Voids poster

Below I describe the design process of the poster, which is available in various color schemes.

The distances on the poster are all light-travel distances. To learn more about how distances are measured in the Universe, I've put together a short tutorial and calculator on space expansion, light-travel and comoving distances.

The reference section links to reading material about the details of individual elements, such as the coordinate system.

## 2 · Inspiration

I was motivated by this map by Richard Powell of the Universe within 2 billion light years.

This is a map of all the major known superclusters within two billion light years plotted onto the supergalactic plane. Each point on this map is a rich cluster of galaxies containing hundreds of galaxies as listed in Abell's catalog of rich clusters of galaxies. This map does not show every rich cluster but only those which are grouped together into large supercluster formations. Each of these superclusters must also contain hundreds or maybe thousands of smaller groups of galaxies. This map is clearly not complete, the plane of our galaxy runs approximately down the centre of the map and most astronomers prefer to study galaxies that are far away from this plane where there is a lot less gas and dust obscuring our view of the universe. This explains why most of the known superclusters are on the left and right sides of the map (original caption by Richard Powell). (source)

I started dutifully tracing the map and I got as far as the image below...

Beginning tracing the map by Richard.

...before I decided that I should just parse Richard's list of superclusters and programmatically generate the map.

$#Common Name Equatorial Supergal Redsh Dis Size Con Abell clusters in the # Coordinates Coords z Mly Mly in the supercluster # RA Dec L° B° Centaurus 13 00 -32.0 148 -7 0.014 194 150 Cen-Hya 1060,3526,3565,3574,3581 Perseus-Pisces 02 32 +39.8 341 -8 0.016 222 100 Per-And 262,347,426 Pavo-Indus 20 34 -37.0 230 +32 0.017 235 100 Ind-Mic 3656,3698,3742 ...$

You can download a plain-text and tidied version of this file, in which the Abell list for a supercluster is now on a single line.

Below is my first attempt. This is a top-down view of the supergalactic equator. Clusters in the Southern Supergalactic Hemisphere are joined to the equator plane by dotted lines.

Superclusters projected top-down on the supergalactic equator.

I liked the angled view of Richard's map, so I adjusted the code to achieve this.

Superclusters projected projected on the supergalactic equator. View angle is about 15 degrees.

I knew I wanted to draw the voids on the map, so I scraped some coordinates from Wikipedia's List of Voids and added them to the map.

Superclusters and voids projected on the supergalactic equator. View angle is about 15 degrees.

The object on the far left is the Eridanus Void, which is a hypothesized void to explain the CMBR Cold Spot. I wanted this in the map, but the scale made it difficult—Richard's list of clusters only went out as far as about 2.7 billion light-years but The Eridanus Void is between 6 and 10 billion light years away.

To accomodate this void on the map I needed either (a) more superclusters to fill out the map and/or (b) scale the distance with a log (e.g. $log(d)$) or power transformation (e.g. $d^k$).

There was also another issue: my code implemented an erzats 2-dimensional projection, not an actual orthographic or perspective 2d projection.

## 3 · VizieR astronomical catalogues

For more data, I went to the VizieR database of astronomical catalogues. It's a little clunky but offers a portal to an absolutely immense amount of data. Once you gain familiarity with the interface, it can feel like the Universe is within reach.

I made use of the Abell catalogue and the supercluster catalogue that groups the Abell clusters into superclusters.

VII/110A Rich Clusters of Galaxies, Abell+, 1989

J/MNRAS/445/4073 Two catalogues of superclusters, Chow-Martinez+, 2014

## 4 · Applying an orthographic projection

When these catalogues are plotted using an authentic projection, the result is the map below.

Superclusters (orange), Abell clusters (blue) and voids (black) from the VizieR catalogues VII/110 and J/MNRAS/445/4073 projected on the supergalactic equator. View angle is 15 degrees.

## 5 · Building the poster

When both hemispheres are shown together, there's a lot of overlap between objects close to the equator. To mitigate this, below is my first attempt at separating the hemispheres and building a poster of the map.

First draft of a poster of superclusters, Abell clusters and voids.

Below is a close crop of a region of the poster. At this point, I'm still using the bitmap Mini 7 Condensed font and including labels for all Abell and superclusters.

Close up of a region of the early draft of the poster.

Each supercluster also has its constellation designation. This tiny detail took a while to work out. The coordinates had to be precessed to 1875 to apply the IAU constellation boundary criteria.

VI/42 Identification of a Constellation From Position, Roman, 1987

## 6 · Adding stars and constellations

To manage the density of the labels—especially the constellation labels—I thought it would be better to simply show the constellations. I thought that the natural place to put the constellations would be the surface of the supergalactic sphere at a sufficient distance from the origin to accommodate all the objects within the sphere.

I threw in the sky's brightest 9,110 stars from the Yale Catalogue of Bright Stars.

V/50 Bright Star Catalogue, 5th Revised Ed., Hoffleit+, 1991

I obtained the list of constellation shapes from Marc van der Sluys' list. For each constellation, this list gives the pairs of stars in the Yale Catalogue of Bright Stars that are connected by the constellation lines.

BSC (Yale Catalogue of Bright Stars) constellation edges. by Marc van der Sluys

However, many of Marc's constellations shapes were not the asterisms sanctioned by the IAU. I therefore corrected all the constellation shapes by manually examining the IAU map and cross-referencing the stars to the Yale Catalogue of Bright Stars. Ugh.

My list of IAU constellation shapes conveniently includes the J2000 right ascension and declination for each stars in the pair, along with their HR index, magnitude and name.

For example, Cassiopeia's familiar "W" appears as 4 lines that indicate the connections between HR stars 21-168-264-403-542.

$Cas 21 2.294583 59.149722 2.27 bet Caph|bet Cas|11 Cas 168 10.127083 56.537222 2.23 alf Schedar|alf Cas|18 Cas Cas 168 10.127083 56.537222 2.23 alf Schedar|alf Cas|18 Cas 264 14.177083 60.716667 2.47 gam BU 499A|BU 1028|gam Cas|27 Cas Cas 264 14.177083 60.716667 2.47 gam BU 499A|BU 1028|gam Cas|27 Cas 403 21.454167 60.235278 2.68 del Ruchbah|BUP 19A|del Cas|37 Cas Cas 403 21.454167 60.235278 2.68 del Ruchbah|BUP 19A|del Cas|37 Cas 542 28.598750 63.670000 3.38 eps Segin|eps Cas|45 Cas$

For more details about the constellations see my IAU Constellation Shape Resources.

## 7 · Colors, fonts and design choices

At this point, I went with a vibrant magenta background and switch to the Gotham typeface for the text. I also separeated the hemispheres completely, which makes the map look a little like the hemispheres of the brain. And that's ok.

The constellations and stars from the Yale Catalogue of Bright Stars projected on the supergalactic sphere.

Once I dropped the Abell clusters, superclusters and voids into the sphere, it was beginning to look crowded.

Clusters, superclusters and voids in the North Supergalactic Hemisphere, together with constellations and stars.

From the close crop below, you can see that the drop lines for each object are clusttering the space.

Close crop of clusters, superclusters and voids in the North Supergalactic Hemisphere, together with constellations and stars.

I struggled with these drop lines. On one hand, I thought they were very important because they anchored the objects to the equator and thus provided a better sense of the object's position. On the other hand, they added to the busyness of the map. Ultimately I settled on a compromise. An object's drop line would only be drawn if it didn't have a neighbouring object of the same type.

## 8 · A poetic collaboration

I'm very eager to find ways to combine my work with poetry.

This poster features a poem by Viorica Hrincu. It's about nothingness and the somethingness that can arise from it, if we find it. It appears on the bottom right of the poster. Tucked, but not away.

null
from an undefined
place,
undefined
create (a place)
an account
of us
— Viorica Hrincu

Previously, I've collaborated with Paolo Marcazzan for my 2017 $\pi$ Day $\pi$ in the Sky poster. There, Paolo contributed "Of Black Body", a poem about thermodynamics, constellations and the truth we might find there. For Paolo, the poem hints at our plight (and flight): "For the earthbound, the questions and concerns remain those of identity, passage, escape from transiency, and slow tempering of hope."

## 9 · Interpretive panels and stories

It's likely that neither the coordinate system nor the elements in this map are familiar to most people. Supergalactic what? And what do you mean comoving isn't the first step in cohabitation?

To make the poster accessible, I started adding panels around the map that explained what is drawn, how to read the map, the coordinate system, what superclusters and voids are. I also threw in a few mythological stories, such as the one about Orion and his dogs and about Eridanus.

Also explained are the difference between light-travel and comoving distance along with small graphs that illustrate these concepts.

Adding stories and interpretive panels to the poster— close to a final version.
news + thoughts

# Annals of Oncology cover

Wed 14-09-2022

My cover design on the 1 September 2022 Annals of Oncology issue shows 570 individual cases of difficult-to-treat cancers. Each case shows the number and type of actionable genomic alterations that were detected and the length of therapies that resulted from the analysis.

An organic arrangement of 570 individual cases of difficult-to-treat cancers showing genomic changes and therapies. Apperas on Annals of Oncology cover (volume 33, issue 9, 1 September 2022).

Pleasance E et al. Whole-genome and transcriptome analysis enhances precision cancer treatment options (2022) Annals of Oncology 33:939–949.

My Annals of Oncology 570 cancer cohort cover (volume 33, issue 9, 1 September 2022). (more)

Browse my gallery of cover designs.

A catalogue of my journal and magazine cover designs. (more)

# Survival analysis—time-to-event data and censoring

Fri 05-08-2022

Love's the only engine of survival. —L. Cohen

We begin a series on survival analysis in the context of its two key complications: skew (which calls for the use of probability distributions, such as the Weibull, that can accomodate skew) and censoring (required because we almost always fail to observe the event in question for all subjects).

We discuss right, left and interval censoring and how mishandling censoring can lead to bias and loss of sensitivity in tests that probe for differences in survival times.

Nature Methods Points of Significance column: Survival analysis—time-to-event data and censoring. (read)

Dey, T., Lipsitz, S.R., Cooper, Z., Trinh, Q., Krzywinski, M & Altman, N. (2022) Points of significance: Survival analysis—time-to-event data and censoring. Nature Methods 19:906–908.

# 3,117,275,501 Bases, 0 Gaps

Sun 21-08-2022

See How Scientists Put Together the Complete Human Genome.

My graphic in Scientific American's Graphic Science section in the August 2022 issue shows the full history of the human genome assembly — from its humble shotgun beginnings to the gapless telomere-to-telomere assembly.

Read about the process and methods behind the creation of the graphic.

3,117,275,501 Bases, 0 Gaps. Text by Clara Moskowitz (Senior Editor), art direction by Jen Christiansen (Senior Graphics Editor), source: UCSC Genome Browser.

# Anatomy of SARS-Cov-2

Tue 31-05-2022

My poster showing the genome structure and position of mutations on all SARS-CoV-2 variants appears in the March/April 2022 issue of American Scientist.

Deadly Genomes: Genome Structure and Size of Harmful Bacteria and Viruses (zoom)

An accompanying piece breaks down the anatomy of each genome — by gene and ORF, oriented to emphasize relative differences that are caused by mutations.

Deadly Genomes: Genome Structure and Size of Harmful Bacteria and Viruses (zoom)

# Cancer Cell cover

Sat 23-04-2022

My cover design on the 11 April 2022 Cancer Cell issue depicts depicts cellular heterogeneity as a kaleidoscope generated from immunofluorescence staining of the glial and neuronal markers MBP and NeuN (respectively) in a GBM patient-derived explant.

LeBlanc VG et al. Single-cell landscapes of primary glioblastomas and matched explants and cell lines show variable retention of inter- and intratumor heterogeneity (2022) Cancer Cell 40:379–392.E9.

My Cancer Cell kaleidoscope cover (volume 40, issue 4, 11 April 2022). (more)

Browse my gallery of cover designs.

A catalogue of my journal and magazine cover designs. (more)

# Nature Biotechnology cover

Sat 23-04-2022

My cover design on the 4 April 2022 Nature Biotechnology issue is an impression of a phylogenetic tree of over 200 million sequences.

Konno N et al. Deep distributed computing to reconstruct extremely large lineage trees (2022) Nature Biotechnology 40:566–575.

My Nature Biotechnology phylogenetic tree cover (volume 40, issue 4, 4 April 2022). (more)

Browse my gallery of cover designs.

A catalogue of my journal and magazine cover designs. (more)