Circos > news

Circos Maps Cancer Landscapes

Nature features an article by Heidi Ledford, The Cancer Genome Challenge, which discusses the progress and challenges of identifying structural variation signatures in cancer genomes.

Circos images are used throughout the piece, taken from the COSMIC project (Catalogue of Somatic Mutations in Cancer).

6Ledford H 2010 Big science: The cancer genome challenge Nature 464 (7291) 972-974.

// cancer-genome-challenge

Circos Collaborates with Wired

When Wired needed an inforgraphic to illustrate the complex world of relationships on the TV Series Lost, it turned to Circos.

The task was to visually represent about 60 relationships shared between 35 characters. The tableviewer utility, which applies Circos to visualizing tabular data, was perfect for creating the illustration.

// wired-03

Circos Maps Cancer Landscapes

Nature features an article by Heidi Ledford, The Cancer Genome Challenge, which discusses the progress and challenges of identifying structural variation signatures in cancer genomes.

Circos images are used throughout the piece, taken from the COSMIC project (Catalogue of Somatic Mutations in Cancer).

6Ledford H 2010 Big science: The cancer genome challenge Nature 464 (7291) 972-974.

// cancer-genome-challenge

Circos Collaborates with Wired

When Wired needed an inforgraphic to illustrate the complex world of relationships on the TV Series Lost, it turned to Circos.

In collaboration with Christy Sheppard, Wired's Art Director, Martin Krzywinski created the illustration for the April 22 2010 issue.

// wired-01

Circos Collaborates with Wired

When Wired needed an inforgraphic to illustrate the complex world of relationships on the TV Series Lost, it turned to Circos.

The task was to visually represent about 60 relationships shared between 35 characters. The tableviewer utility, which applies Circos to visualizing tabular data, was perfect for creating the illustration. And thus, Circos says goodbye to the table.

// wired-04

Circos Collaborates with Wired

When Wired needed an inforgraphic to illustrate the complex world of relationships on the TV Series Lost, it turned to Circos.

In collaboration with Christy Sheppard, Wired's Art Director, Martin Krzywinski created the illustration for the April 22 2010 issue.

// wired-01

DHL Uses Circos

Deutsche Post DHL uses Circos in a printed advertisement for the Mail & Logistics Group

// dhl

DHL Uses Circos

Deutsche Post DHL uses Circos in a printed advertisement for the Mail & Logistics Group

// dhl

For other references to Circos usage and items of note, see examples of published images and Circos citations.

News

Showing categories: cover (8 items)
28 April 2010

In 2008, I worked with Pearson publishers to create a cover for iGenetics (3rd ed) by Peter Russell. I just received a copy of the award won by the book's cover illustration.

Circos iGenetics book cover - recognized at the 39th annual Bookbuilders West Book Show (781 x 400)
13 May 2009

An image created by Circos appears on the cover of the EMBO Journal (6 May 2009, vol 28, no 9). The image is a crop of a comparison of 4 genomes (human, chimp, mouse and zebrafish) which is available at full resolution as part of a poster.

Circos image on EMBO Journal cover (394 x 517)
Figure. Cover of The Embo Journal (6 May 2009, vol 28, no 9).
7 January 2009

Circos appears in Designing Universal Knowledge (buy at Amazon), a compilation of infographic methods by Gerlinde Schuller.

Circos - Circular Genome Data Visualization (765 x 457)
1 December 2008

Circos is on the cover of Building Bioformatics Solutions with Perl, R and MySQL by Conrad Bessant, Ian Shadforth, and Darren Oakley (Oxford Press).

Building Bioformatics Solutions (344 x 450)
11 October 2008

In collaboration with Volumina, Circos was used to generate illustrations for Chromosomes exhibition, an art book of still images from David Cronenberg films.

Illustrations created with Circos used in Chromosomes, an exhibition by David Cronenberg. (500 x 508)

I had the opportunity to contribute not only the art work, but text for this book as well.

Illustrations created with Circos used in Chromosomes, an exhibition by David Cronenberg. (800 x 267)

We fear the unknown. Monsters and creatures are words we give to the most frightening unknown of all — the biological. Things living — primitive, unpredictable, ravenous and without recourse to emotion or reason. Clutching reason and humanity, we congratulate ourselves for having departed those base instincts.

But our departure is neither recent nor complete. Inside each of us is a history of our evolutionary ancestors, written in our chromosomes. The ant has 2. The house fly, 12. Humans have 46, a dog has 78 and in a fern, there are over 1,000. Chromosomes are the superblocks of genetic organization and heredity. They are an organism's contact list of its evolutionary ancestors.

Many of these ancestors were not different from monsters and creatures that inhabit our nightmares, our fears and our movies. And as the lights come on, and projections from the screen yield to reality, our body harbors elements from a darker past. Like the Alu genetic element, a jumping-gene which repeatedly copies itself within our genome and a constant companion to our evolution for the past 65 million years. In every part of every chromosome is our creature heritage.

Although we emerged in human from our mother's womb, as embryos we exhibited our evolutionary history: we all had gills, a tail, and body hair. Lost or absorbed before birth, these signposts remind us that our ancestors are inside us, not just in stories or movies. It is only later that the brain, our species' most prized possession, develops and transforms us. In the last minute, we pass into humanity and into the world. Today, we tell stories of monsters and creatures. Tomorrow, we may take their place. Distant from now, our progeny will see our forms during development and say "What creatures we were." Movies will frighten by showing our forms. "Look, mommy, a smooth-skinned biped with wide eyes."

2 October 2008

I worked with Pearson publishers to create a cover for iGenetics (3rd ed) by Peter Russell.

Circos book cover - iGenetics by Peter Russell, 3rd ed (331 x 450)
12 June 2008

American Scientist cover, which I created with Circos, wins Silver EXCEL Award in the Cover Illustration category from Society of National Association Publications (SNAP).

Circos - Circular Genome Data Visualization (150 x 184)

"The cover graphic is a dramatic visual representation of some of the chromosomal connections between the dog and human genomes," Schoonmaker said. "It helps readers understand how physical differences between dogs and humans, and between one dog and another, can be so large, even though they share much genetically." (more).

9 August 2007

Circos appears on the cover of American Scientist (Sept/Oct issue). The image accompanies the article Genetics and the Shape of Dogs by Elaine Ostrander. Read about the figure.

Circos - Circular Genome Data Visualization (400 x 490)