Trance opera—Spente le Stellebe dramaticmore quotes
very clickable
visualization + math

The 2022 π Day art is a music album composed by Greg Coles for solo piano. It tells stories from the very beginning (314…) to the very (known) end of π (…264) as well as math (Wallis Product) and math jokes (Feynman Point), repetition (nn) and zeroes (null).

$\pi$ Day 2020 Art — Digits, poetically.

2021 $\pi$ reminds us that good things grow for those who wait.' edition.
2019 $\pi$ has hundreds of digits, hundreds of languages and a special kids' edition.
2018 $\pi$ day stitches street maps into new destinations.
2017 $\pi$ day imagines the sky in a new way.

2016 $\pi$ approximation day wonders what would happen if about right was right.
2016 $\pi$ day sees digits really fall for each other.
2015 $\pi$ day maps transcendentally.
2014 $\pi$ approx day spirals into roughness.

2014 $\pi$ day hypnotizes you into looking.
2014 $\pi$ day
2013 $\pi$ day is where it started
Circular $\pi$ art and other distractions

On March 14th celebrate $\pi$ Day. Hug $\pi$—find a way to do it.

For those who favour $\tau=2\pi$ will have to postpone celebrations until July 26th. That's what you get for thinking that $\pi$ is wrong. I sympathize with this position and have $\tau$ day art too!

If you're not into details, you may opt to party on July 22nd, which is $\pi$ approximation day ($\pi$ ≈ 22/7). It's 20% more accurate that the official $\pi$ day!

Finally, if you believe that $\pi = 3$, you should read why $\pi$ is not equal to 3.

Most of the art is available for purchase as framed prints and, yes, even pillows. Sleep's never been more important — I take custom requests.
3 Little $\pi$,
1 what
4 can you tell us?

Welcome to this year's celebration of $\pi$ and mathematics. Among the chaos of CORVID-19, this year $\pi$ Day celebrations are short poetic emissions I call “piku”. They are brief pauses for the time.

Start by reading how piku are constructed and then browse submitted piku. Consider participating by submitting your own piku. All you need is a pen and a few (small) words. Very therapeutic.

But if the words here don't help, immerse yourself in my coronavirus art. It's quite catching.

If you enjoy poetry and words, see how I convert spam into poems in the style of ee cummings and if you like to see words arrange on page, look through my typographic art.

3 Piku are
1 brief
4 pauses just in
1 time.

You may know the haiku (俳句) as a short three line poem whose lines traditionally have 5, 7 and 5 syllables (specifically, morae or phonetic sounds).

Scribbles on Shonan Village Center notepad on which the idea was born. I am grateful for being invited to the Formalizing Biological and Medical Visualization (Shonan Meeting 167) in which the idea formed. (zoom)

On a recent trip to Japan I was looking to my environment for inspiration for this year's $\pi$ Day. I also really wanted a scheme that would allow people to contribute to the art so that everyone could be both a participant and an audience.

After scribbling for a little bit (or a long while), I came up with the idea of a piku ($\pi$ku, パイク). Analogously to a haiku, the piku is poem whose structure is constrained. But in this case, the constraints are the digits of $\pi$ itself.

The piku

The simplest piku is a 3 phrase poem with 3, 1 and 4 syllables, respectively. Perhaps the most trivial piku is just the list of digits.

3 Three one four
1 One
4 Five nine two six.

Specifically, Haiku count the number of phonetic sounds which isn't always the same as syllables. For example, the word "any" has two such sounds: a-ny.

If you're interested in how the counting of sounds is done in Japanese, read about marking time and beats in Haiku.

But a more fun one would be

3 A Three and
1 A
4 One and a four.

Longer words can be used, of course. But watch out for the lines that require a single syllable.

3 Numbers are
1 all
4 Equally fun.
3 Land meets sky.
1 Oh,
4 It's you again!

You can use hyphenation to work around the syllable count.

3 Memories
1 for-
4 get yourself then.

plural of piku is piku

Piku is singulare tantum—its plural form is the same as its singular.

This is because its inspiration is the haiku and in Japanese nouns do not have different singular and plural forms,

3 Piku is
1 the
4 piku plural.

Longer piku

In general, a piku may have more than 3 lines. This reflects the fact that the digits of $\pi$ do not terminate.

3 Land meets sky.
1 Oh,
4 It's you again!
1 Yes,
5 Who did you expect?

The endless piku is just waiting to be written. Well... started, at least.

Handling zeros

The digit zero is a line with no syllables and corresponds to a compulsory verse break. But because the first zero in $\pi$ is at digit 33, you wouldn't see a verse break for a while.

Therefore, you're free to introduce a verse break anywhere in the piku (this does not use up a digit). For example,

3 Hot air breeze
1 cools
4 much hotter things.

3 F 0 0
1 red

Generalizing the piku — the nku

Any number, $n$, has its own nku. The rules for its construction are the same: each digit generates a line with corresponding number of syllables.

For example, the haiku is an nku for $n = 575$.

The year of your birth has an nku—you might want to try composing one to reflect on your origins.

In fact, any date (e.g. DDMMYYYY) can be made into an nku. This year's $\pi$ date in this format is 14032020 and here's one possible nku.

1 Dust
4 in space vacuum
0
3 clogs alien
2 machines.
0
2 Bummer.
0

The trailing zero in the number creates a verse break at the end of a poem. This can be ignored or used to generate a blank line if the poem is set with other text on the page.

news + thoughts

Cell Genomics cover

Mon 16-01-2023

Our cover on the 11 January 2023 Cell Genomics issue depicts the process of determining the parent-of-origin using differential methylation of alleles at imprinted regions (iDMRs) is imagined as a circuit.

Designed in collaboration with with Carlos Urzua.

Our Cell Genomics cover depicts parent-of-origin assignment as a circuit (volume 3, issue 1, 11 January 2023). (more)

Akbari, V. et al. Parent-of-origin detection and chromosome-scale haplotyping using long-read DNA methylation sequencing and Strand-seq (2023) Cell Genomics 3(1).

Browse my gallery of cover designs.

A catalogue of my journal and magazine cover designs. (more)

Thu 05-01-2023

My cover design on the 6 January 2023 Science Advances issue depicts DNA sequencing read translation in high-dimensional space. The image showss 672 bases of sequencing barcodes generated by three different single-cell RNA sequencing platforms were encoded as oriented triangles on the faces of three 7-dimensional cubes.

My Science Advances cover that encodes sequence onto hypercubes (volume 9, issue 1, 6 January 2023). (more)

Kijima, Y. et al. A universal sequencing read interpreter (2023) Science Advances 9

Browse my gallery of cover designs.

A catalogue of my journal and magazine cover designs. (more)

Regression modeling of time-to-event data with censoring

Mon 21-11-2022

If you sit on the sofa for your entire life, you’re running a higher risk of getting heart disease and cancer. —Alex Honnold, American rock climber

In a follow-up to our Survival analysis — time-to-event data and censoring article, we look at how regression can be used to account for additional risk factors in survival analysis.

We explore accelerated failure time regression (AFTR) and the Cox Proportional Hazards model (Cox PH).

Nature Methods Points of Significance column: Regression modeling of time-to-event data with censoring. (read)

Dey, T., Lipsitz, S.R., Cooper, Z., Trinh, Q., Krzywinski, M & Altman, N. (2022) Points of significance: Regression modeling of time-to-event data with censoring. Nature Methods 19.

Music video for Max Cooper's Ascent

Tue 25-10-2022

My 5-dimensional animation sets the visual stage for Max Cooper's Ascent from the album Unspoken Words. I have previously collaborated with Max on telling a story about infinity for his Yearning for the Infinite album.

I provide a walkthrough the video, describe the animation system I created to generate the frames, and show you all the keyframes

Frame 4897 from the music video of Max Cooper's Asent.

The video recently premiered on YouTube.

Renders of the full scene are available as NFTs.

Gene Cultures exhibit — art at the MIT Museum

Tue 25-10-2022

I am more than my genome and my genome is more than me.

The MIT Museum reopened at its new location on 2nd October 2022. The new Gene Cultures exhibit featured my visualization of the human genome, which walks through the size and organization of the genome and some of the important structures.

My art at the MIT Museum Gene Cultures exhibit tells shows the scale and structure of the human genome. Pay no attention to the pink chicken.

Annals of Oncology cover

Wed 14-09-2022

My cover design on the 1 September 2022 Annals of Oncology issue shows 570 individual cases of difficult-to-treat cancers. Each case shows the number and type of actionable genomic alterations that were detected and the length of therapies that resulted from the analysis.

An organic arrangement of 570 individual cases of difficult-to-treat cancers showing genomic changes and therapies. Apperas on Annals of Oncology cover (volume 33, issue 9, 1 September 2022).

Pleasance E et al. Whole-genome and transcriptome analysis enhances precision cancer treatment options (2022) Annals of Oncology 33:939–949.

My Annals of Oncology 570 cancer cohort cover (volume 33, issue 9, 1 September 2022). (more)

Browse my gallery of cover designs.

A catalogue of my journal and magazine cover designs. (more)