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# dna: deep

Scientific graphical abstracts — design guidelines

# data visualization + art + finding your way

As the night comes on, the signs reveal the mystery of the cell.
Solve the puzzle.
Enjoy the sign as posters and 4k desktops.

# DNA on 10th — Science this way

The signs encode the sequence in the following way

How DNA sequence is encoded on the signs. Complementary bases ($A/T$) and ($C/G$) are mirror images of each other. Repeats are shown with a small circle (base repeats twice) or a large circle (base repeats three times). Longer repeats are shown by combinations of these shapes, as shown by the example $ATTCGGGGGT$ sequence on the right.

To understand the contents shown below, see Design & Methods.

The length of row sequences varies because a single symbol can encode 1 (e.g. A), 2 (e.g. AA) or 3 bases (e.g. AAA).

## south sign

$row gene mutation helix dir code N sequence 92 KRTAP2 C>T 5 ← GTCGACGACGACXCGTGT 2105 GTCCGGGACGACGACC/TCGGTGGT 91 MRPS10 G>C 3 → AAXTGATGTGCACTACAG 2082 AAAAG/CTTTGGATGTGCAACTACAAG 90 BRCA1 A>G 5 ← TCTCGACACAXTCTGTCG 2057 TCTTCGACACAA/GTCTTGTCG 89 NEGR1 G>A 3 → CTGXTCGACCTATACTAC 2037 CCCTGG/ATCCGACCCCTTATACTTAC 88 CACNA1G C>T 5 ← CGACACGAXCGTAGACAC 2012 CGACACGAC/TCCGTAGGACAC 87 CKAP2 C>T 3 → CACAGXGTAGAGAGTATC 1992 CACAGC/TGTAGAGAAGTTATCC 86 MYO9A G>A 5 ← CGCGTCXCTCACACTCTA 1971 CGCGTTCG/ACTTCACACTTCTAA 85 ADSSL1 A>G 3 → AGGTGTXCGCTGCGTGCG 1949 AGGGGTGGTA/GCGGCTGCGGTGCG 84 RAF1 T>C 5 ← TACTXATGACTACGACGC 1926 TAACCTT/CATGACTACGACGC 83 GCNT3 C>T 3 → GTGTCGAGXGTCATCGAG 1906 GTGTCGAGC/TGTCATCGGAAAG 82 OR2M7 C>A 5 ← ATAXTCTCATAAGTAGAC 1885 ATAAAC/ATTCTCCAATAAAAGTAGAC 81 ROCK1 G>A 3 → CTCGATGTCTAXTCGACT 1860 CCCTCGATGTTCTAG/ATCGAACTT 80 TP53 C>T 5 ← CAXATGTCAGACGTACGC 1837 CAC/TATTGTCAAGGACGTACCCGC 79 PCDHA2 C>T 3 → GACGTACTATAGXAGACG 1814 GACGTTACTAATAAGC/TAAAGAACG 78 SHTN1 C>A 5 ← AXTCTCTATGTACTACTA 1790 AC/ATTCTCTATTTGTAACTACTA 77 CENPE G>A 3 → TACTAGATTGTGAGXTCT 1768 TACTAGATTTTGTTGAGG/ATTCTTT 76 IFI44 C>T 5 ← AXCTTGTCTGAGTGACTC 1744 AAC/TCTTTTGTCTGGAGTGACTC 75 MMP17 C>A 3 → CTGCGCGTGACAGAGXAT 1722 CTGCGCGTGGAACAGGAGC/AAT 74 OR4D6 C>T 5 ← GAXTAGAGTCTATCTACT 1701 GAAC/TTAAAGAGTCCCTTATCTACT 73 NRAS T>C 3 → ATGACTATGTCGACTGXT 1677 ATGACCTATGTCGACCTGT/CT 72 HNRNPAB C>G 5 ← AGAXTGCAGTCACACTAG 1657 AGAAC/GTGGCAGGTCACAACCCTAGG 71 EXTL1 G>A 3 → GTCGTCTGTCGTCTCGXT 1632 GGTCGTCCTGTTCGTCCTCGG/AT 70 GSE1 G>T 5 ← GAGAXAGCGTCGTAGAGC 1610 GAGAG/TAGCGTCGTAGGAGGC 69 KRAS T>G 3 → GAGCTGTGTCGTCAGTXC 1590 GAGCTGTGTCGTCCAGTT/GC 68 ZNF43 G>C 5 ← TGTAGAXTGATGATGTGT 1571 TGGGTTAGGAG/CTTTGGAATGATGTGT 67 OLR1 C>T 3 → GTCAGATGAGAGTACXAC 1545 GTCAAAGAAATGAGAGGTACC/TACC 66 CYP7B1 G>A 5 ← TGACACACXCTCTCTGAC 1521 TGACACACG/ACTTTCCCTCTGAACC 65 NF2 C>T 3 → GAGACGACGAGAGXGAGC 1497 GAAGACGAACCGAGAAGC/TGAGGC 64 OBSCN G>A 5 ← AGCAGACATGXTGTATGA 1474 AAGGGCAGGAACATGG/ATGTATTGGA 63 LIPC C>T 3 → ACTCCTGACGAGXGCATG 1449 AAACTTCCCCCTGACCCGAGC/TGCAATG 62 TP53 G>A 5 ← GTACACATGTCAXGACGT 1422 GTACACATTGTCAAG/AGACGT 61 POLE T>C 3 → CTCTAGAGCAXTGACAGA 1402 CTTCTAGAGCAT/CTGACAGGA 60 ADSSL1 A>G 5 ← TGTCGAGAGGTGTXCGCT 1382 TGTCGAGGAGGGGTGGTA/GCGGCT 59 NKX2 C>T 3 → ACAGAGACXTGACACTCG 1359 ACCAGAGGACC/TTTGACCACTCCGG 58 OPRM1 G>A 5 ← GACTACTATCGAGTAXTA 1335 GACTACCTAAATCGGGAGTAG/ATA 57 SYT1 G>A 3 → CAGTGCXGTAGAGTCATG 1312 CCAGTGCG/AGTAAGGAGTCAATG 56 TP53 C>T 5 ← ATGTACACATGTCAGAXG 1290 ATGTACACATTGTCAAGGAC/TG 55 RAF1 T>C 3 → TACTXATGACTACGACGC 1269 TAACCTT/CATGACTACGACGC 54 EFCAB2 A>G 5 ← CTAGTGCGTGACGTGAXG 1249 CTAGTGCGGTGACGTGAA/GG 53 PTPN6 C>A 3 → GAGXGTGTACTGACTACA 1230 GGAGC/AGTGTACTGGAACTACA 52 EVPLL G>T 5 ← GAGTCGACGACGCAGAXG 1209 GAAGTCCGACGACGGGCAGAG/TG 51 RASGRF2 G>T 3 → GAXGACGCACTCACGATG 1187 GAG/TGACCGCACTCCCACGATTG 50 TRAV9 T>A 5 ← TCTATGATCGACTCTXAT 1165 TCTATGATTCGGACCTCTT/AAT 49 EZH2 A>G 3 → TXTGACACTCTCATCGTG 1144 TTA/GTGACACCTCTCCATTCCGTG 48 NXPE2 A>C 5 ← GATGCACTCGACTCXGTC 1121 GATGCACCCTCCGACTCA/CGTCC 47 KRAS C>G 3 → AXCACGCATCGTCTCACG 1099 AC/GCACCGCATCCGTTCTCACGG 46 ERBB2 T>C 5 ← TCGATGAGTCTCXGACTC 1077 TCGATGAGTCCTCT/CGACTCC 45 CTNNB1 A>G 3 → ACXTCACGTGTCTACTAG 1057 ACCA/GTCACCGTGGTCTTACCTAAG 44 SNRPN T>C 5 ← TGAGTATACGAXTGTGAG 1033 TGAGGTTATACCGAAAT/CTGGTGGAG 43 ERBB2 T>C 3 → CTCXGACTCGTCTCTACG 1008 CCTCT/CGACTCCGTCCTCTTAACG 42 CMYA5 C>G 5 ← AGAGTACGTXATGACTAC 985 AGGAGGTACGTC/GATTTGGACTTTAC 41 NCF2 C>A 3 → TGACXTCAGTCTCCTATA 960 TGGACC/ATCAAAGTCCTTCCCCTATA 40 TP53 C>T 5 ← ACGTACGXCGTACTGCTC 935 ACGTACCCGC/TCGTACTTGGCCTCC 39 EPAS1 G>T 3 → CACAGAXGTCAGTCGAGT 911 CACAGAG/TGTTCAGGTCGAGT 38 TP53 C>A 5 ← TACGCXGTACTGCTCGTA 891 TACCCGCC/AGTACTTGGCCTCCGGGTA 37 IGHV2 G>C 3 → TACTATATXATGTCGTGT 865 TACTATTTATG/CATGTCGTGT 36 CTNNB1 A>G 5 ← CACXTCACGTGTCTACTA 845 CACCA/GTCACCGTGGTCTTACCTAA 35 SAV1 G>A 3 → TCTGAGACAGXCTATATA 821 TCTGAGACCAAGGG/ACTATAATAA 34 EP300 C>T 5 ← CTXTGTGACTCGACTGCG 798 CTC/TTGTGACCTCGAACTGGCG 33 MOCOS C>T 3 → AGCTCGACGAGAXCTCTG 777 AAAGCTCGACCGAGAC/TCCTCTTG 32 OR5H6 G>A 5 ← AXGTCTACTCTGTATCTG 754 AAAG/AGTCTACTCTTGTTAATCTGG 31 ZNF589 C>G 3 → TCATACTGAGACGAXTAG 730 TCCATACCTGAAGACCGAAAC/GTAAG 30 KLRG1 T>C 5 ← GXTCAGACTGAGATGTGT 705 GT/CTTCAGACTGGAAGAATGTGT 29 NDEL1 G>A 3 → GTAGACTCGCTCGCGXCT 683 GTAGACTCGCTCGGGCGG/ACT 28 EVPLL G>T 5 ← AXGACGACACGACGTCGA 663 AG/TGACGACCACGACGTCCCGGA 27 GNA13 G>A 3 → CTCACGCTCGCTCGTCXT 641 CTCACCGCTCCGGCTCGTCG/ATT 26 HSPG2 C>T 5 ← CAXCGACTCATAGCGACA 619 CAC/TCGGGACCTCATAGCGACA 25 TRABD G>C 3 → TCGCGCCTCGTCAGAGXA 598 TCGCCCGCCCCTCGTCAGAGG/CA 24 B2M A>G 5 ← CTGAXTGGTGATGATAGA 576 CTGAA/GTGGGGTGAATTGATAGAA 23 ITIH1 C>T 3 → CTGAGTGCGCAGTGAGXC 553 CCTGAGTGGCGGCCAGTGAGC/TC 22 TP53 G>A 5 ← TACTGXCTCGTAGAGTGT 531 TACTTGG/ACCTCCGGGTAGGAGTGGT 21 MARC2 G>A 3 → CGCTCTCGACTCGCGXTA 506 CGCCTCCTCGACCTTCGCGGG/ATA 20 TP53 C>T 5 ← CGTACTGXCTCGTAGAGT 483 CCGTACTTGGC/TCTCCGGGTAGGAGT 19 PIK3CA A>G 3 → CACAGTCGTGTACTXCAC 458 CAACAGGTCGGTGGTACTA/GCAC 18 SNRPN T>C 5 ← AGTATACGAXTGTGAGAC 436 AGGTTATACCGAAAT/CTGGTGGAGAACC 17 LRRC34 C>A 3 → AGTCTCACTACTXTATTC 409 AGGTTCTTCACCTACTTC/ATTTAATTTTTC 16 EP300 C>T 5 ← CGTAGCTGTGAXCGTCGT 380 CCGTAAGGCTGTGAC/TCGTTCGT 15 ADSSL1 A>G 3 → CGAGAGGTGTXCGCTGCG 358 CGAGGAGGGGTGGTA/GCGGCTGCGG 14 HRNR G>C 5 ← ACAGACAGTCGATXAGAG 334 ACAGACCAAGTCCGATG/CAGAAG 13 CDKN2B C>T 3 → GCCGTGCGXTGCACGTCA 312 GCCCCGGTGGCGC/TTGCAACGTCCCA 12 TP53 C>A 5 ← TACGCGTACTGCTCXGTA 287 TACCCGCCGTACTTGGCCTCC/AGGGTA 11 IGHV2 G>C 3 → CTATATXATGTCGTGTAG 261 CTATTTATG/CATGTCGTGTAG 10 EZH2 T>G 5 ← TACTAGTAGAGTCTAXGA 241 TTTACTTAAGTAGAGTCTTAT/GGA 9 MRPS10 G>C 3 → TCAAXTGATGTGCACTAC 218 TCAAAAG/CTTTGGATGTGCAACTAC 8 CTNNB1 A>G 5 ← GAGTCTCTCTCGACACXT 194 GAGTCTCTTCCTCGACACCA/GT 7 RAF1 T>C 3 → ACTXATGACTACGACGCA 173 AACCTT/CATGACTACGACGCA 6 EFCAB2 A>G 5 ← CTAGTGCGTGACGTGAXG 153 CTAGTGCGGTGACGTGAA/GG 5 C20ORF96 C>A 3 → TCXTCACTGAGACTCGTG 134 TCC/ATTCACTTGAAGGACTCGTG 4 NRAS G>T 5 ← ATGACTATGTCGACTXTC 112 ATGACCTATGTCGACCTG/TTTC 3 APC C>T 3 → AXCGTGTCACGAGAGTAC 91 AAC/TCCGGTGTTCACGAGAGTAC 2 CHD4 G>A 5 ← AGTCTATAGATCGAXCTC 69 AGTTCTTATTTAAAGATCGAG/ACTTCC 1 CDKN2A T>C 3 → TXGACGCGCTGGCGTGAG 43 TT/CGACGCGGCTGGGGCGGTGAG 0 BRCA1 A>G 5 ← TGATCTCGACACAXTCTG 21 TTGATCTTCGACACAA/GTCTTG$

## north sign

$row gene mutation helix dir code N sequence 92 KMT2D C>T 5 → GTGTGXTGCTGCTGCTGC 2098 GTTGTTGC/TTGCTGCTGCTGC 91 MRPS10 G>C 3 ← GACATCACGTGTAGTXAA 2078 GAACATCAACGTGTAGGTTTG/CAAAA 90 B2M A>G 5 → TAGTGGTXAGTCTACATC 2053 TTAAGTGGGGTA/GAGTCTTACATTC 89 NEK10 T>A 3 ← ACACTATATCAGCTXGAT 2029 ACCACTAATAAATTCAGCTT/AGGAT 88 CTNNB1 G>T 5 → AGTCTACTGXACTCTGAT 2005 AGTCTTACCTGG/TACTCTGGAAT 87 CD84 C>T 3 ← AGCAGAGCAGATXCATAG 1983 AGGCAAAGGAGCAAGATC/TCATAGG 86 MALRD1 C>A 5 → TGATGATCTGTXATATGA 1959 TTGATGATCTGTC/AATTTATGGA 85 ADSSL1 A>G 3 ← GCGTGCGTCGCXTGTGGA 1937 GCGTGGCGTCGGCA/GTGGTGGGGA 84 RAF1 T>C 5 → CGCAGCATCAGTAXTCAT 1914 CGCAGCATCAGTAT/CTCCAAT 83 GRK5 G>T 3 ← TTATGCGCAXAGATCTCT 1894 TTTTATGCGGCAG/TAGATCCTCT 82 OPRM1 G>A 5 → TGTCTCTGTAGAATXATG 1872 TGTCTTCCTGTAAAGAAAATG/AATG 81 RASA3 G>A 3 ← AGTCTCXGAGATGTGTGG 1848 AGTTTCCTCG/AGAAGATGGTGTTGGGG 80 TP53 C>T 5 → CGCATGCAGACTGTAXAC 1822 CGCCCATGCAGGAACTGTTAC/TAC 79 PIM1 C>T 3 ← GCGTGXAGATCTCTCGAC 1799 GCCGGTGC/TAAGATCTCTTCGAC 78 SYNDIG1 G>A 5 → AGCGTGCTGCGCTCTGXG 1777 AGGGCGTGCTGCGCTCCTGG/AGGG 77 CELF2 G>A 3 ← CTCXTCTGCAGCAGCCAC 1754 CCTCG/ATCTGGCAGCAAGGCCCCAC 76 IFI44 C>T 5 → CTCAGTGAGTCTGTTCXA 1730 CTCAGTGAGGTCTGTTTTCC/TAA 75 MKI67 G>A 3 ← CTXATGTCATCTCTGGAG 1708 CTG/AAATGTCCATCTCTGGGGAGG 74 OR4K1 C>T 5 → ATCATTGATCGTGTCXGA 1685 ATCATTTTGATCGGTGTCC/TGA 73 NXPE2 A>C 3 ← GXCTCAGCTCACGTAGCT 1664 GA/CCTCAGCCTCCCACGTAGCT 72 ST7 A>G 5 → CTGCTACTGCTCATXTGA 1643 CCTGCTTACTGCTTCATTA/GTGGA 71 ERBB2 G>A 3 ← CXCTCACTGCTGAGACGA 1620 CCG/ACTCACTGCTGGAGGACGA 70 GJE1 C>T 5 → CTTCTGATCGATCXGATA 1599 CCCTTTTCTTTGGATCGATCC/TGAATA 69 KRAS T>G 3 ← CXTGACTGCTGTGTCGAG 1573 CT/GTGACCTGCTGTGTCGAG 68 TRIM46 T>C 5 → CTCGAGCTGAGXAGAGAT 1554 CTCGGGAGGCTGAGGT/CAGGAGAAT 67 OR5H6 G>T 3 ← TGXAGTCTCTATTACACT 1530 TGG/TAGTCTCTATTTTACACT 66 CCDC154 G>A 5 → TGCAGCTCTXCGCAGCCA 1510 TGGCCAGCTCCTG/ACCGCAGGGCCCCAA 65 NWD2 C>T 3 ← GCTCXAGAGACGCATGAG 1483 GCTCC/TAGAAGACCCGCATGAAG 64 ORMDL3 G>A 5 → CGCTGCTXGTCGGTCTCA 1461 CGCCTTGCCCTG/AGTCCGGGGTCTCAAA 63 LMTK3 G>T 3 ← GCAGCXAGAGCGAGAGCT 1434 GCCAGCG/TAGAGCCGGGAGAGCCT 62 TP53 G>A 5 → TGCAGXACTGTACACATG 1411 TGCAGG/AAACTGTTACACATG 61 POLE T>C 3 ← CTGTAGCXTCAGTCTCTG 1391 CTGTAGCCCT/CTCCAGTTCCTTCCTG 60 ADSSL1 A>G 5 → TCGCXTGTGGAGAGCTGT 1366 TCGGCA/GTGGTGGGGAGGAGCTGT 59 NF1 C>T 3 ← CTGCTGAGCXTCACAGAC 1343 CTGCTGAAAGCC/TTTCACAAGACC 58 OR2M7 C>A 5 → CTXATATGATGTGTCATG 1320 CTTC/AAAATATTGATGTGTCATTG 57 SLC25A24 G>A 3 ← CTGATATCGTCXAGAGCA 1297 CTTTGGAAATAATTCGTCG/AAAAGAGGCCAA 56 TP53 C>T 5 → GXAGACTGTACACATGTA 1267 GC/TAGGAACTGTTACACATGTA 55 RAF1 T>C 3 ← CGCAGCATCAGTAXTCAT 1246 CGCAGCATCAGTAT/CTCCAAT 54 EFCAB2 A>G 5 → GXAGTGCAGTGCGTGATC 1226 GA/GAGTGCAGTGGCGTGATC 53 PIK3CA G>A 3 ← GTGATGTATATCGAXACA 1207 GTGAATGTAAATATTCGAG/AACA 52 EPAS1 G>T 5 → GXAGACACTGCACTATAT 1185 GG/TAGACACTGGCACCCTATAT 51 RNF40 C>T 3 ← CAGACTCTCAGTCTCXGA 1164 CAGAACTCCTCAAGGGTCTCC/TGA 50 TPO C>A 5 → TGXGCGACCTACGAGTAG 1141 TGC/AGCGGACCCCTACGAGTTAGG 49 LINC00207 A>G 3 ← TCTGCTGCTGCATCTGXA 1118 TCCTGCTGCTGCATCTTGA/GA 48 NRAS T>C 5 → TCTXGTCAGCTGTATCAG 1098 TTCTT/CGTCCAGCTGTATCCAG 47 KRAS C>G 3 ← AGCACTCTGCTACGCAXC 1077 AGGCACTCTTGCCTACGCCAC/GC 46 ERBB2 T>C 5 → CTCAGXCTCTGAGTAGCT 1055 CCTCAGT/CCTCCTGAGTAGCT 45 CTNNB1 A>G 3 ← GATCATCTGTGCACTXCA 1035 GAATCCATTCTGGTGCCACTA/GCCA 44 SNRPN T>C 5 → GAGTGTXAGCATATGAGT 1011 GAGGTGGTT/CAAAGCCATATTGGAGT 43 ERBB2 T>C 3 ← GCATCTCTGCTCAGXCTC 986 GCAATTCTCCTGCCTCAGT/CCTCC 42 CMYA5 C>G 5 → CATCAGTAXTGCATGAGA 963 CATTTCAGGTTTAC/GTGCATGGAGGA 41 NUDT17 C>A 3 ← GAGAGACAGCGTCXTCGC 938 GAGAGGACAAGCCGTCC/ATCGC 40 TP53 C>T 5 → CTCGTCATGCXGCATGCA 917 CCTCCGGTTCATGCC/TGCCCATGCA 39 EMID1 C>T 3 ← GCACTACTCAGXGAGTGC 893 GGCACCTACCTTCAGC/TGAGTGC 38 TP53 C>A 5 → ATGCTCGTCATGXCGCAT 871 ATGGGCCTCCGGTTCATGC/ACGCCCAT 37 IGHV2 G>C 3 ← TGTGCTGTAXTATATCAT 845 TGTGCTGTAG/CTATTTATCAT 36 CTNNB1 A>G 5 → ATCATCTGTGCACTXCAC 825 AATCCATTCTGGTGCCACTA/GCCAC 35 SOGA1 G>A 3 ← TGCTGTCXCAGCTCTGCA 801 TGCTGTCG/ACAGCTCCTGCA 34 EBF1 C>T 5 → AGTCGCACTCGTCGTXCA 782 AGTCGCACCTCCCGTCGTC/TCA 33 MFSD11 C>T 3 ← TAGCTXATAGCTCTGAGT 761 TAGCTC/TATAGCTCTGAGT 32 OR5H6 G>A 5 → GTCTATGTCTCATCTGXA 743 GGTCTAATTGTTCTCATCTGG/AAAA 31 KMT2D C>G 3 ← TGTXCTGAGACATGCACT 719 TTGTC/GCTTGAAGAACATGCACTT 30 CENPC G>C 5 → CTATCTGAGATGATCTXA 696 CTATTCTGAGATGATCCTG/CA 29 NF1 G>A 3 ← GAXGACTGTGCTGACGAC 676 GAAG/AGACTGTTGCTGACGAC 28 EGFR C>T 5 → CACGTGCAGCTCATCAXG 656 CCACCGTGCAGCTCATCAC/TG 27 GML G>A 3 ← GXGACTACAGTGAGATGC 636 GG/AGACTTACAGTTTGAGATGCC 26 HDAC9 C>T 5 → ACACGCAGCACAGCTXAG 614 ACACGGCAGCACCAGGCTC/TAG 25 TM7SF3 T>C 3 ← AXGCTGTATCAGCACTCT 593 AT/CGCCTGTAATCCCAGCACTCT 24 FGF7 A>G 5 → CTGAGCAGAGATCXCTGA 571 CTGAGGCAGGAGAATCA/GCTTGAA 23 IKBKB C>T 3 ← CXGAGATGTCTGAGGATG 548 CCC/TGAGATGTCCCTGAGGGGATG 22 TP53 G>A 5 → TGTGAGATGCTCXGTCAT 525 TGGTGAGGATGGGCCTCCG/AGTTCAT 21 MAN2A1 G>A 3 ← TGXCTGAATATATAGTAT 500 TGG/ACTGGAAAATAATATAGGTAT 20 TP53 C>T 5 → TGAGATGCTCXGTCATGC 477 TGAGGATGGGCCTCC/TGGTTCATGCC 19 PRSS27 A>G 3 ← CTCXTGTCTCAGCTGCTG 452 CCTCA/GTGTCCTCAGGCCTGGCTGGG 18 SNRPN T>C 5 → CAGAGTGTXAGCATATGA 427 CCAAGAGGTGGTT/CAAAGCCATATTGGA 17 LPA G>A 3 ← AGCTCXATACTCTGTCAT 400 AGCCTCG/AATAACTCTGTCCAT 16 EP300 C>T 5 → GCTAGTXCTATGAGTATG 379 GCTAGTC/TCTATGGGAGTAAATGG 15 ADSSL1 A>G 3 ← GCGTCGCXTGTGGAGAGC 356 GGCGTCGGCA/GTGGTGGGGAGGAGC 14 HRNR G>C 5 → GAGAXTAGCTGACAGACA 332 GAAGAG/CTAGCCTGAACCAGACA 13 CLDN18 C>T 3 ← CTCTGTGTCXGAGAGAGC 310 CTCCTGTGTCC/TGAGAGAGC 12 TP53 C>A 5 → ATGXCTCGTCATGCGCAT 291 ATGGGC/ACTCCGGTTCATGCCGCCCAT 11 IGHV2 G>C 3 ← GATGTGCTGTAXTATATC 265 GATGTGCTGTAG/CTATTTATC 10 RAF1 C>G 5 → ATXTGGAGCATATCTCGC 245 ATC/GTGGGGAGGCATATCCTCGGC 9 MRPS10 G>C 3 ← CATCACGTGTAGTXAACT 222 CATCAACGTGTAGGTTTG/CAAAACT 8 CMYA5 C>G 5 → AXTGCATGAGAGCACAGA 198 AC/GTGCATGGAGGAGCCACAAGA 7 RAF1 T>C 3 ← ACGCAGCATCAGTAXTCA 176 ACGCAGCATCAGTAT/CTCCAA 6 EFCAB2 A>G 5 → GXAGTGCAGTGCGTGATC 156 GA/GAGTGCAGTGGCGTGATC 5 CREB5 C>A 3 ← ACAGCATGCAGAGATXAC 137 AACAGCCATGCAGAAAGAATC/AAC 4 NALCN G>T 5 → GTXATCATGTCTAGTGAC 114 GTTTG/TATCCATGTCTTAGTGACC 3 ATM C>T 3 ← ACACTCTCGCACGAGCXG 91 ACACTTCTCGCAAACGAGCC/TG 2 CDC25C T>A 5 → CTCXGCTCACTGTGATAT 70 CTTCT/AGCTCACCTGTTTGGGAATAT 1 CTNNB1 T>C 3 ← TGCACTACACAGCTCTXC 45 TGCCACTACCACAGCTCCTT/CC 0 BRAF C>G 5 → CTGTXCATGATCAGATCA 24 CTGTTC/GCAAATGATCCAGATCCAA$