Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - contact me Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca on Twitter Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Lumondo Photography
This love loves love. It's a strange love, strange love.Liz Fraserwatch


Circos at British Library Beautiful Science exhibit—Feb 20–May 26


art + science

Bloomberg Businessweek Design Conference — San Francisco, 2013

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Design loves science and science loves design, but doesn't always know it. (Bloomberg Businessweek)

science design

Together with Alberto Cairo, I presented at the Bloomberg Businessweek Design Conference (highlights) on the topic of design and communication in the sciences.

Alberto, as the journalist, motivated why communication should include access to detail through an engaging narrative. He made the distinction between the specialist (heavy on detail) and the communicator (focus on narrative) and emphasized that the distinction is artificial, though often played out (watch video).

I, as the scientist, underscored the importance of clear communication between scientists. As the specialists, they are often very poor communicators. Pick up any science journal and you'll quickly discover that scientists either aren't good at telling stories or are discouraged to do so by the medium. The consequence is the same: papers read like a wall of text. TL;DR anyone? The quality of visual communication in general ranges from muddled to abysmal (watch video).

We need more leaders in the field, such as Nature Publishing Group, to reward and emphasize good visual communication (e.g. Nature Cancer Review 2013 Figure Calendar).

Our presentations concluded with a 15 minute moderated discussion with Sam Grobart, senior Businesssweek writer. Everyone got a little cheeky. Good fun.

presentation video

Watch: my presentation, conversation with Alberto Cairo, moderated by Sam Grobart. (Bloomberg TV), Albert Cairo's presentation.

presentation slides

This was a lightning 7 minute talk. I did more planning about what to say than I usually do, given that there was virtually no opportunity for any kind of backtracking, and include a running narrative below each slide.

Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
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download presentation

My slides are available as PDF, keynote (zipped) or Quicktime. The format is 16:9 HD.

Bloomberg Businessweek Design Issue

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
The reality of redesign is disruptive. How can we pursue new ideas and opportunities without leaving consumers confused or angry? Businessweek puts that question to some of the world's most accomplished designers. (Bloomberg Businessweek Design Issue)

On 28 Jan 2013, Bloomberg Businessweek Design Issue will capture the ideas from the conference and the personalities that generated them.

During the conference, each talk was captured in a series of sketches by Tom Wujec: my talk sketch and moderated discussion sketch.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Date completed: ongoing — an accurate assessment of the state of the visual communication field in science. (read article)

news + thoughts

Mind your p's and q's

Sat 29-03-2014

In the April Points of Significance Nature Methods column, we continue our and consider what happens when we run a large number of tests.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Comparing Samples — Part II — Multiple Testing. (read)

Observing statistically rare test outcomes is expected if we run enough tests. These are statistically, not biologically, significant. For example, if we run N tests, the smallest P value that we have a 50% chance of observing is 1–exp(–ln2/N). For N = 10k this P value is Pk=10kln2 (e.g. for 104=10,000 tests, P4=6.9×10–5).

We discuss common correction schemes such as Bonferroni, Holm, Benjamini & Hochberg and Storey's q and show how they impact the false positive rate (FPR), false discovery rate (FDR) and power of a batch of tests.

Krzywinski, M. & Altman, N. (2014) Points of Significance: Comparing Samples — Part II — Multiple Testing Nature Methods 11:215-216.

Krzywinski, M. & Altman, N. (2014) Points of Significance: Comparing Samples — Part I — t-tests Nature Methods 11:215-216.

Krzywinski, M. & Altman, N. (2013) Points of Significance: Significance, P values and t-tests Nature Methods 10:1041-1042.

Happy Pi Day— go to planet π

Fri 21-03-2014

Celebrate Pi Day (March 14th) with the art of folding numbers. This year I take the number up to the Feynman Point and apply a protein folding algorithm to render it as a path.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Digits of Pi form landmass and shoreline. (details)

For those of you who liked the minimalist and colorful digit grid, I've expanded on the concept to show stacked ring plots of frequency distributions.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Frequency distribution of digits of Pi in groups of 6 up to the Feynman Point. (details)

And if spirals are your thing...

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Frequency distribution of digits of Pi in groups of 4 up to digit 4,988. (details)

Have data, will compare

Fri 07-03-2014

In the March Points of Significance Nature Methods column, we continue our discussion of t-tests from November (Significance, P values and t-tests).

We look at what happens how uncertainty of two variables combines and how this impacts the increased uncertainty when two samples are compared and highlight the differences between the two-sample and paired t-tests.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Comparing Samples — Part I. (read)

When performing any statistical test, it's important to understand and satisfy its requirements. The t-test is very robust with respect to some of its assumptions, but not others. We explore which.

Krzywinski, M. & Altman, N. (2014) Points of Significance: Comparing Samples — Part I Nature Methods 11:215-216.

Krzywinski, M. & Altman, N. (2013) Points of Significance: Significance, P values and t-tests Nature Methods 10:1041-1042.

Circos at British Library Beautiful Science Exhibit

Thu 06-03-2014

Beautiful Science explores how our understanding of ourselves and our planet has evolved alongside our ability to represent, graph and map the mass data of the time. The exhibit runs 20 February — 26 May 2014 and is free to the public. There is a good Nature blog writeup about it, a piece in The Guardian, and a great video that explains the the exhibit narrated by Johanna Kieniewicz, the curator.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Circos at the British Library Beautiful Science exhibit. (about exhibit)
Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Mailed invitation to the exhibit features my science art. (zoom)

I am privileged to contribute an information graphic to the exhibit in the Tree of Life section. The piece shows how sequence similarity varies across species as a function of evolutionary distance. The installation is a set of 6 30x30 cm backlit panels. They look terrific.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Circos Circles of Life installation at Beautiful Science exhibit at the British Library. (zoom)

Think outside the bar—box plots

Fri 31-01-2014

Quick, name three chart types. Line, bar and scatter come to mind. Perhaps you said pie too—tsk tsk. Nobody ever thinks of the box plot.

Box plots reveal details about data without overloading a figure with a full frequency distribution histogram. They're easy to compare and now easy to make with BoxPlotR (try it). In our fifth Points of Significance column, we take a break from the theory to explain this plot type and—I hope— convince you that they're worth thinking about.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Visualizing samples with box plots. (read)

The February issue of Nature Methods kicks the bar chart two more times: Dan Evanko's Kick the Bar Chart Habit editorial and a Points of View: Bar charts and box plots column by Mark Streit and Nils Gehlenborg.

Krzywinski, M. & Altman, N. (2014) Points of Significance: Visualizing samples with box plots Nature Methods 11:119-120.