Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - contact me Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca on Twitter Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Lumondo Photography Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Pi Art Martin Krzywinski / Genome Sciences Center / mkweb.bcgsc.ca - Hilbertonians - Creatures on the Hilbert Curve
Without an after or a when.Papercut feat. Maiken Sundbycan you hear the rain?more quotes


In Silico Flurries: Computing a world of snow. Scientific American. 23 December 2017


art + science

Bloomberg Businessweek Design Conference — San Francisco, 2013

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Design loves science and science loves design, but doesn't always know it. (Bloomberg Businessweek)

science design

Together with Alberto Cairo, I presented at the Bloomberg Businessweek Design Conference (highlights) on the topic of design and communication in the sciences.

Alberto, as the journalist, motivated why communication should include access to detail through an engaging narrative. He made the distinction between the specialist (heavy on detail) and the communicator (focus on narrative) and emphasized that the distinction is artificial, though often played out (watch video).

I, as the scientist, underscored the importance of clear communication between scientists. As the specialists, they are often very poor communicators. Pick up any science journal and you'll quickly discover that scientists either aren't good at telling stories or are discouraged to do so by the medium. The consequence is the same: papers read like a wall of text. TL;DR anyone? The quality of visual communication in general ranges from muddled to abysmal (watch video).

We need more leaders in the field, such as Nature Publishing Group, to reward and emphasize good visual communication (e.g. Nature Cancer Review 2013 Figure Calendar).

Our presentations concluded with a 15 minute moderated discussion with Sam Grobart, senior Businesssweek writer. Everyone got a little cheeky. Good fun.

presentation video

Watch: my presentation, conversation with Alberto Cairo, moderated by Sam Grobart. (Bloomberg TV), Albert Cairo's presentation.

presentation slides

This was a lightning 7 minute talk. I did more planning about what to say than I usually do, given that there was virtually no opportunity for any kind of backtracking, and include a running narrative below each slide.

Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
Martin Krzywinski - Bloomberg Businessweek Design Conference 2013
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download presentation

My slides are available as PDF, keynote (zipped) or Quicktime. The format is 16:9 HD.

Bloomberg Businessweek Design Issue

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
The reality of redesign is disruptive. How can we pursue new ideas and opportunities without leaving consumers confused or angry? Businessweek puts that question to some of the world's most accomplished designers. (Bloomberg Businessweek Design Issue)

On 28 Jan 2013, Bloomberg Businessweek Design Issue will capture the ideas from the conference and the personalities that generated them.

During the conference, each talk was captured in a series of sketches by Tom Wujec: my talk sketch and moderated discussion sketch.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Date completed: ongoing — an accurate assessment of the state of the visual communication field in science. (read article)
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news + thoughts

Two-level factorial experiments

Fri 22-03-2019
To find which experimental factors have an effect, simultaneously examine the difference between the high and low levels of each.

Two-level factorial experiments, in which all combinations of multiple factor levels are used, efficiently estimate factor effects and detect interactions—desirable statistical qualities that can provide deep insight into a system.

They offer two benefits over the widely used one-factor-at-a-time (OFAT) experiments: efficiency and ability to detect interactions.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Two-level factorial experiments. (read)

Since the number of factor combinations can quickly increase, one approach is to model only some of the factorial effects using empirically-validated assumptions of effect sparsity and effect hierarchy. Effect sparsity tells us that in factorial experiments most of the factorial terms are likely to be unimportant. Effect hierarchy tells us that low-order terms (e.g. main effects) tend to be larger than higher-order terms (e.g. two-factor or three-factor interactions).

Smucker, B., Krzywinski, M. & Altman, N. (2019) Points of significance: Two-level factorial experiments Nature Methods 16:211–212.

Background reading

Krzywinski, M. & Altman, N. (2014) Points of significance: Designing comparative experiments.. Nature Methods 11:597–598.

Happy 2019 `\pi` Day—
Digits, internationally

Tue 12-03-2019

Celebrate `\pi` Day (March 14th) and set out on an exploration explore accents unknown (to you)!

This year is purely typographical, with something for everyone. Hundreds of digits and hundreds of languages.

A special kids' edition merges math with color and fat fonts.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
116 digits in 64 languages. (details)
Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
223 digits in 102 languages. (details)

Check out art from previous years: 2013 `\pi` Day and 2014 `\pi` Day, 2015 `\pi` Day, 2016 `\pi` Day, 2017 `\pi` Day and 2018 `\pi` Day.

Tree of Emotional Life

Sun 17-02-2019

One moment you're :) and the next you're :-.

Make sense of it all with my Tree of Emotional life—a hierarchical account of how we feel.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
A section of the Tree of Emotional Life.

Find and snap to colors in an image

Sat 29-12-2018

One of my color tools, the colorsnap application snaps colors in an image to a set of reference colors and reports their proportion.

Below is Times Square rendered using the colors of the MTA subway lines.


Colors used by the New York MTA subway lines.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Times Square in New York City.
Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Times Square in New York City rendered using colors of the MTA subway lines.
Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Granger rainbow snapped to subway lines colors from four cities. (zoom)

Take your medicine ... now

Wed 19-12-2018

Drugs could be more effective if taken when the genetic proteins they target are most active.

Design tip: rediscover CMYK primaries.

More of my American Scientific Graphic Science designs

Ruben et al. A database of tissue-specific rhythmically expressed human genes has potential applications in circadian medicine Science Translational Medicine 10 Issue 458, eaat8806.