data visualization + celebration
Genome Sciences Center 20th Anniversary Clothing, Music, Drinks and Art
On 15 November 2019, the Genome Sciences Center held its 20th anniversary celebration.
Here you can read about the design of the evening's clothing, music, drinks and other art.
After silence, that which comes nearest to expressing the inexpressible is music.
— Aldous Huxley
Music
We commissioned Segue to create a unique ambient music landscape for the celebration.
Segue is the name used by Jordan Sauer, an electronic music producer from Vancouver, BC. He creates ambient electronic music with layers of field recordings, acoustic and electronic sounds, creating sonic soundscapes that conjure images of nature and emotions of peace and introspection. He has release numerous solo albums and collaborations with artists from around the world, and recently released a solo album “The Island” on the Silent Season record label in summer 2019. Jordan is thrilled to partner with the GSC in the production of “Gene Machines”.
gene machines
Gene machines will be available as a digital download soon. We are also planning to have a vinyl release.
An assembly of shifting soundscapes, textures and rhythmic loops produced by the laboratory machines.
In commemoration of the 20th anniversary of Canada’s Michael Smith Genome Sciences Centre, Segue was comissioned to create an original composition based on audio recordings from the GSC’s laboratory equipment, robots and computers—to make “music” from the noise they produce.
Machine noise is a challenging palette of musical ingredients—sharp, abrasive and whirring sounds are typically unpleasant. For one night, these machines are repurposed as acoustical performers.
In the process of creating “Gene Machines”, recordings were analyzed for their specific frequency profiles and then used to generate melodic or percussive sounds. Together with bass from a Moog synthesizer, the sounds were then stretched, manipulated and sequenced into a series of compositions. Each composition is based on the recording from one specific laboratory machine, emphasizing its tone and timbre quality.
Cell Genomics cover
Our cover on the 11 January 2023 Cell Genomics issue depicts the process of determining the parent-of-origin using differential methylation of alleles at imprinted regions (iDMRs) is imagined as a circuit.
Designed in collaboration with with Carlos Urzua.
Akbari, V. et al. Parent-of-origin detection and chromosome-scale haplotyping using long-read DNA methylation sequencing and Strand-seq (2023) Cell Genomics 3(1).
Browse my gallery of cover designs.
Science Advances cover
My cover design on the 6 January 2023 Science Advances issue depicts DNA sequencing read translation in high-dimensional space. The image showss 672 bases of sequencing barcodes generated by three different single-cell RNA sequencing platforms were encoded as oriented triangles on the faces of three 7-dimensional cubes.
More details about the design.
Kijima, Y. et al. A universal sequencing read interpreter (2023) Science Advances 9
Browse my gallery of cover designs.
Regression modeling of time-to-event data with censoring
If you sit on the sofa for your entire life, you’re running a higher risk of getting heart disease and cancer. —Alex Honnold, American rock climber
In a follow-up to our Survival analysis — time-to-event data and censoring article, we look at how regression can be used to account for additional risk factors in survival analysis.
We explore accelerated failure time regression (AFTR) and the Cox Proportional Hazards model (Cox PH).
Dey, T., Lipsitz, S.R., Cooper, Z., Trinh, Q., Krzywinski, M & Altman, N. (2022) Points of significance: Regression modeling of time-to-event data with censoring. Nature Methods 19.
Music video for Max Cooper's Ascent
My 5-dimensional animation sets the visual stage for Max Cooper's Ascent from the album Unspoken Words. I have previously collaborated with Max on telling a story about infinity for his Yearning for the Infinite album.
I provide a walkthrough the video, describe the animation system I created to generate the frames, and show you all the keyframes
The video recently premiered on YouTube.
Renders of the full scene are available as NFTs.
Gene Cultures exhibit — art at the MIT Museum
I am more than my genome and my genome is more than me.
The MIT Museum reopened at its new location on 2nd October 2022. The new Gene Cultures exhibit featured my visualization of the human genome, which walks through the size and organization of the genome and some of the important structures.
Annals of Oncology cover
My cover design on the 1 September 2022 Annals of Oncology issue shows 570 individual cases of difficult-to-treat cancers. Each case shows the number and type of actionable genomic alterations that were detected and the length of therapies that resulted from the analysis.
Pleasance E et al. Whole-genome and transcriptome analysis enhances precision cancer treatment options (2022) Annals of Oncology 33:939–949.
Browse my gallery of cover designs.
