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data visualization + celebration

Genome Sciences Center 20th Anniversary Clothing, Music, Drinks and Art

On 15 November 2019, the Genome Sciences Center held its 20th anniversary celebration.

Here you can read about the design of the evening's clothing, music, drinks and other art.

Distrust any enterprise that requires new clothes.
— Henry David Thoreau (Walden)

clothing

BC Cancer Genome Sciences Center 20th Anniversary Celebration / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Luke and Mayia wearing limited edition volunteer t-shirts. The pattern reproduces the human genome with chromosomes as spirals. (zoom)
BC Cancer Genome Sciences Center 20th Anniversary Celebration / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Dr. Mungall revealing his personal side: DNA socks. In his hand, the 'improved outcome', one of the signature cocktails created for the celebration. (zoom)
BC Cancer Genome Sciences Center 20th Anniversary Celebration / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Paul and Nazanin show off their party swag. (zoom)

t-shirt

BC Cancer Genome Sciences Center 20th Anniversary Celebration / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
The relative lengths of human chromosomes. (zoom)
BC Cancer Genome Sciences Center 20th Anniversary Celebration / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Human chromosomes proportionately represented as spirals. Maybe you can notice something about the start and direction of each spiral. (zoom)
BC Cancer Genome Sciences Center 20th Anniversary Celebration / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Chromosome spirals snuggled into a square. (zoom)
BC Cancer Genome Sciences Center 20th Anniversary Celebration / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Chromosome spiral t-shirt design. (zoom)
BC Cancer Genome Sciences Center 20th Anniversary Celebration / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Knitted tag signalling the authenticity of the anniversary swag. (zoom)

socks

BC Cancer Genome Sciences Center 20th Anniversary Celebration / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Left- and right-handed forms of DNA. (zoom)
BC Cancer Genome Sciences Center 20th Anniversary Celebration / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Dimensions of the DNA molecule. (zoom)
BC Cancer Genome Sciences Center 20th Anniversary Celebration / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Sock design. The left sock DNA is left-handed and the right sock DNA is right-handed. (zoom)
BC Cancer Genome Sciences Center 20th Anniversary Celebration / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
The knitted socks, as they should be worn. The dots at the small toe indicate the left and right socks. (zoom)

hoodie

BC Cancer Genome Sciences Center 20th Anniversary Celebration / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Warm and cozy hoodie has the GSC logo unwound on the left arm. The anniversary patch is on the back right. (zoom)

lanyard

BC Cancer Genome Sciences Center 20th Anniversary Celebration / Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
The lanyard shows two DNA helices zipping up.
news + thoughts

Cell Genomics cover

Mon 16-01-2023

Our cover on the 11 January 2023 Cell Genomics issue depicts the process of determining the parent-of-origin using differential methylation of alleles at imprinted regions (iDMRs) is imagined as a circuit.

Designed in collaboration with with Carlos Urzua.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Our Cell Genomics cover depicts parent-of-origin assignment as a circuit (volume 3, issue 1, 11 January 2023). (more)

Akbari, V. et al. Parent-of-origin detection and chromosome-scale haplotyping using long-read DNA methylation sequencing and Strand-seq (2023) Cell Genomics 3(1).

Browse my gallery of cover designs.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
A catalogue of my journal and magazine cover designs. (more)

Science Advances cover

Thu 05-01-2023

My cover design on the 6 January 2023 Science Advances issue depicts DNA sequencing read translation in high-dimensional space. The image showss 672 bases of sequencing barcodes generated by three different single-cell RNA sequencing platforms were encoded as oriented triangles on the faces of three 7-dimensional cubes.

More details about the design.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
My Science Advances cover that encodes sequence onto hypercubes (volume 9, issue 1, 6 January 2023). (more)

Kijima, Y. et al. A universal sequencing read interpreter (2023) Science Advances 9

Browse my gallery of cover designs.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
A catalogue of my journal and magazine cover designs. (more)

Regression modeling of time-to-event data with censoring

Mon 21-11-2022

If you sit on the sofa for your entire life, you’re running a higher risk of getting heart disease and cancer. —Alex Honnold, American rock climber

In a follow-up to our Survival analysis — time-to-event data and censoring article, we look at how regression can be used to account for additional risk factors in survival analysis.

We explore accelerated failure time regression (AFTR) and the Cox Proportional Hazards model (Cox PH).

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: Regression modeling of time-to-event data with censoring. (read)

Dey, T., Lipsitz, S.R., Cooper, Z., Trinh, Q., Krzywinski, M & Altman, N. (2022) Points of significance: Regression modeling of time-to-event data with censoring. Nature Methods 19.

Music video for Max Cooper's Ascent

Tue 25-10-2022

My 5-dimensional animation sets the visual stage for Max Cooper's Ascent from the album Unspoken Words. I have previously collaborated with Max on telling a story about infinity for his Yearning for the Infinite album.

I provide a walkthrough the video, describe the animation system I created to generate the frames, and show you all the keyframes

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Frame 4897 from the music video of Max Cooper's Asent.

The video recently premiered on YouTube.

Renders of the full scene are available as NFTs.

Gene Cultures exhibit — art at the MIT Museum

Tue 25-10-2022

I am more than my genome and my genome is more than me.

The MIT Museum reopened at its new location on 2nd October 2022. The new Gene Cultures exhibit featured my visualization of the human genome, which walks through the size and organization of the genome and some of the important structures.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
My art at the MIT Museum Gene Cultures exhibit tells shows the scale and structure of the human genome. Pay no attention to the pink chicken.

Annals of Oncology cover

Wed 14-09-2022

My cover design on the 1 September 2022 Annals of Oncology issue shows 570 individual cases of difficult-to-treat cancers. Each case shows the number and type of actionable genomic alterations that were detected and the length of therapies that resulted from the analysis.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
An organic arrangement of 570 individual cases of difficult-to-treat cancers showing genomic changes and therapies. Apperas on Annals of Oncology cover (volume 33, issue 9, 1 September 2022).

Pleasance E et al. Whole-genome and transcriptome analysis enhances precision cancer treatment options (2022) Annals of Oncology 33:939–949.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
My Annals of Oncology 570 cancer cohort cover (volume 33, issue 9, 1 September 2022). (more)

Browse my gallery of cover designs.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
A catalogue of my journal and magazine cover designs. (more)

© 1999–2023 Martin Krzywinski | contact | Canada's Michael Smith Genome Sciences CentreBC Cancer Research CenterBC CancerPHSA