Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca - contact me Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca on Twitter Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca - Lumondo Photography Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca - Pi Art Martin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca - Hilbertonians - Creatures on the Hilbert CurveMartin Krzywinski / Canada's Michael Smith Genome Sciences Centre / mkweb.bcgsc.ca - Pi Day 2020 - Piku
Twenty — minutes — maybe — more.Naomichoose four wordsmore quotes


The Outbreak Poems — artistic emissions in a pandemic


BCGSC.CA 10TH ANNIV AdrianALLY JianghongAN RuthAPPANAH LukeARMSTRONG JenniferASANO MehranATAEE TimothyAU-YEUNG JosieAUDET HeatherAXAM LanceBAILEY MirunaBALA AdrianaBANUELOS LorenaBARCLAY MishaBILENKY InancBIROL IanBOSDET KarlaBRETHERICK AngelaBROOKS-WILSON MabelBROWN-JOHN RichardBRUSKIEWICH YaronBUTTERFIELD RebeccaCARLSEN MauroCASTELLARIN TimotheeCEZARD SusannaCHAN SimonCHAN JustinCHAN ClintonCHAN SteveCHAND Chi-DanCHANG AnitaCHARTERS DeborahCHEN GraceCHENG DeanCHENG DorothyCHEUNG RodneyCHIN SuganthiCHITTARANJAN ReadmanCHIU StephanieCHO GinaCHOE RobertCHRISP AndyCHU EricCHUAH ElizabethCHUN StellaCHUN LouiseCLARKE AmandaCLARKE RobinCOOPE RichardCORBETT MonicaCORNEAN AdrianCORTES LuluCRISOSTOMO KattyCRUZ CletusD'SOUZA AllenDELANEY AthenaDENG MerindaDENG LindsayDEVORKIN NoreenDHALLA RodDOCKING LisaDREOLINI AdrienneDROBNIES MadaleneEARP AmyENGLISH NoushinFARNOUD AnthonyFEJES CynthiaFERGUSON MatthewFIELD StephaneFLIBOTTE DanFORNIKA DougFREEMAN FrancisFRENO MarilynGILLESPIE BeckyGILLESPIE NatalieGLAVAS SharonGORSKI RodrigoGOYA MalachiGRIFFITH ObiGRIFFITH RanGUIN ImanHAJIRASOULIHA JuliusHALASCHEK-WIENER AdamHALL AdrienneHANNIGAN JenniferHARDIE RubayetHASAN AnHE SeanHENDERSON UljanaHESSE MartinHIRST CarrieHIRST RobertHOLT DanielHORSPOOL ClaireHOU JayneHUNTER TakaakiICHU ShaunJACKMAN CarrieJANG RozminJANOO-GILANI KelseyJEFFERSON JupiterJIANG ChaoyangJIN LindseyJOHNSON JoanneJOHNSON StevenJONES BaljitKAMOH MiraKARIA KatayoonKASAIAN UsmanKHAN JieunKIM HeatherKIRK MartinKRZYWINSKI LetticiaKWONG DarwinLAHUE AnthonyLE StephenLEACH DarleneLEE Hyun-WuLEE AmyLEUNG DidiLEUNG YvonneLI IreneLI SaLI NancyLIAO YuSiLIU KevinMA DianaMAH NawarMALHIS MarcoMARRA CoreyMATSUO RinaMAWJI NasrinMAWJI LorraineMAY MichaelMAYO HelenMCDONALD StephanieMCINNIS HeatherMCMURTRIE Carri-LynMEAD MariaMENDEZ-LAGO SimonHaileMERHU DianeMILLER MichelleMOKSA RichardMOORE AnnieMORADIAN RyanMORIN GreggMORIN OlenaMOROZOVA AndyMUNGALL KarenMUNGALL SarahMUNRO JillMWENIFUMBO Jae-KyungMYUNG RichardNEWSOME JoanNG CydneyNIELSEN KarenNOVIK DianaPALMQUIST PawanPANDOH JohnsonPANG IrenePELOSO LinhPHAN ReneePICHE Anna-LiisaPRABHU TrevorPUGH JennyQIAN LisaRAEBURN RitaRAHARJO MaziarRAHMANI JianhuaREN GordonROBERTSON RobynROSCOE RouzbehROSHANRAVAN SharonRUSCHKOWSKI DanneSA MarianneSADAR MurwanSALAME RolandSANTOS JacquieSCHEIN JohannaSCHUETZ TesaSEVERSON ArashSHAFIEI HeesunSHIN SanjitSINGH RanjitSINGH JaredSLOBODAN DuaneSMAILUS JillianSMITH RichardSOBEL SoranaMORRISSY GregSTAZYK DominikSTOLL CeceliaSURAGH Wing-KaSZE IsabellaTAI AngelaTAM BonnyTAM TeresaTAM SamuelTAN MichelleTANG GregTAYLOR KevinTEAGUE NinaTHIESSEN KenTHORNE TinaTHORNE AncaTOMESCU EvaTRINH ArmelleTROUSSARD MirandaTSAI KaneTSE RichardVARHOL SusanWAGNER GangWANG JeanWANG ReneWARREN DenilWICKRAMA MiriamWILLIAMS GaryWILSON TinaWONG JohnWONG KenWRIGHT JacksonWU NatasjaWYE AlexanderYAKOVENKO GeorgeYANG KevinYANG RunyingYANG DenizYORUKOGLU ThomasZENG XuekuiZHANG YongjunZHAO MiZHOU 261109mk

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news + thoughts

Cover of Nature Genetics August 2020

Mon 03-08-2020

Our design on the cover of Nature Genetics's August 2020 issue is “Dichotomy of Chromatin in Color” . Thanks to Dr. Andy Mungall for suggesting this terrific title.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Dichotomy of Chromatin in Color. Nature Genetics, August 2020 issue. (read more)

The cover design accompanies our report in the issue Gagliardi, A., Porter, V.L., Zong, Z. et al. (2020) Analysis of Ugandan cervical carcinomas identifies human papillomavirus clade–specific epigenome and transcriptome landscapes. Nature Genetics 52:800–810.

Poster Design Guidelines

Wed 15-07-2020

Clear, concise, legible and compelling.

The PDF template is a poster about making posters. It provides design, typography and data visualiation tips with minimum fuss. Follow its advice until you have developed enough design sobriety and experience to know when to go your own way.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Poster Design Guidelines — Clear, concise, legible and compelling..

The SEIRS model for infectious disease dynamics

Thu 18-06-2020

Realistic models of epidemics account for latency, loss of immunity, births and deaths.

We continue with our discussion about epidemic models and show how births, deaths and loss of immunity can create epidemic waves—a periodic fluctuation in the fraction of population that is infected.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: The SEIRS model for infectious disease dynamics. (read)

This column has an interactive supplemental component (download code) that allows you to explore epidemic waves and introduces the idea of the phase plane, a compact way to understand the evolution of an epidemic over its entire course.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Nature Methods Points of Significance column: The SEIRS model for infectious disease dynamics. (Interactive supplemental materials)

Bjørnstad, O.N., Shea, K., Krzywinski, M. & Altman, N. (2020) Points of significance: The SEIRS model for infectious disease dynamics. Nature Methods 17:557–558.

Background reading

Bjørnstad, O.N., Shea, K., Krzywinski, M. & Altman, N. (2020) Points of significance: Modeling infectious epidemics. Nature Methods 17:455–456.

Gene Machines

Fri 05-06-2020

Shifting soundscapes, textures and rhythmic loops produced by laboratory machines.

In commemoration of the 20th anniversary of Canada's Michael Smith Genome Sciences Centre, Segue was commissioned to create an original composition based on audio recordings from the GSC's laboratory equipment, robots and computers—to make “music” from the noise they produce.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Gene Machines by Segue. Now available on vinyl.

Virus Mutations Reveal How COVID-19 Really Spread

Mon 01-06-2020

Genetic sequences of the coronavirus tell story of when the virus arrived in each country and where it came from.

Our graphic in Scientific American's Graphic Science section in the June 2020 issue shows a phylogenetic tree based on a snapshot of the data model from Nextstrain as of 31 March 2020.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Virus Mutations Reveal How COVID-19 Really Spread. Text by Mark Fischetti (Senior Editor), art direction by Jen Christiansen (Senior Graphics Editor), source: Nextstrain (enabled by data from GISAID).

Cover of Nature Cancer April 2020

Mon 27-04-2020

Our design on the cover of Nature Cancer's April 2020 issue shows mutation spectra of patients from the POG570 cohort of 570 individuals with advanced metastatic cancer.

Martin Krzywinski @MKrzywinski mkweb.bcgsc.ca
Each ellipse system represents the mutation spectrum of an individual patient. Individual ellipses in the system correspond to the number of base changes in a given class and are layered by mutation count. Ellipse angle is controlled by the proportion of mutations in a class within the sample and its size is determined by a sigmoid mapping of mutation count scaled within the layer. The opacity of each system represents the duration since the diagnosis of advanced disease. (read more)

The cover design accompanies our report in the issue Pleasance, E., Titmuss, E., Williamson, L. et al. (2020) Pan-cancer analysis of advanced patient tumors reveals interactions between therapy and genomic landscapes. Nat Cancer 1:452–468.


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